Navigation Links
A single mild blast exposure can cause brain injuries with similarities to Alzheimer's disease
Date:9/24/2013

A new study published in the September issue of the Journal of Alzheimer's Disease reports that even a single mild explosion can cause changes in the brain that have similarities to those found in diseases like Alzheimer's disease and chronic traumatic encephalopathy.

Flying debris or getting thrown against other objects are not the only things that make explosions so dangerous. The primary shock waves that emanate from explosions also can kill a person if they are intense enough. However, most blast survivors experience less powerful shock waves that cause less severe immediate symptoms, such as temporary disorientation or headaches, but on the surface leave victims apparently unscathed. Scientists are especially concerned when these mild blast exposures happen repeatedly--likening them to the repetitive hits endured by boxers and other athletes.

"Some of the big questions in mild traumatic brain injury are about a molecule called tau" said Dr. David Cook of VA Puget Sound Health Care System and University of Washington. "In many brain diseases, tau gets chemically modified to create something called 'phospho-tau'. Phospho-tau is important because it is the starting building block of 'tau tangles', which can build up over time and damage brain cells."

The Seattle team used a rodent laboratory model to study brain changes caused by mild blast exposure. Dr. Cook noted, "We were a bit surprised to find that after only a single mild blast, phospho-tau remained elevated for at least a month."

"Tau pathology is part of end-stage TBI," said Dr. Iboja Cernak of the University of Alberta, Canada and a co-author on this report, "so, it is very interesting to discover that persistent phospho-tau increases also appear to be part of earlier phases of blast-induced neurotrauma".

These new findings raise the possibility that early-intervention with tau-based treatments may someday prove valuable in treating blast-induced neurotrauma.


'/>"/>

Contact: VA Puget Sound Health Care System Office of Public Affairs
publicaffairspugetsound@va.gov
206-764-2317
IOS Press
Source:Eurekalert

Related medicine news :

1. CNT Market - SWCNTs and MWCNTs Market (Single-Walled And Multi-Walled Carbon Nanotubes) worth US$3.3 Billion by 2016 - New Report by MarketsandMarkets
2. Imprivata is the Most Widely Selected Single Sign-On Solution by U.S. Hospitals Using McKesson Paragon or Horizon According to HIMSS Analytics
3. PlentyOfFish Acquires FastLife - the World’s Largest Speed Dating and Singles Event Company
4. Positive Singles Launched STD Support Features like STD Counselor and STD Treatment Stories
5. PositiveSingles.com Is Here To Stay
6. Bikerkiss.com Is a Biker Dating Site Which Is Now Helping Single Bikers to Find Love and Riding Partners
7. Nation’s First Robotic Single Incision (via Belly Button) Hernia Repair, Performed in an Outpatient Setting at K and B Surgical Center
8. More Than One Hundred Thousand American Single Moms Have Joined MillionaireMatch.com
9. PositiveSingles.com Launches A Unique New Feature That Will Notify Users When The Recipient Has Read Emails That They Send
10. Love is in the Air for HIV Positive Individuals at PositiveSingles.com
11. Darius Rucker to Perform Hit Single on MDA Show of Strength Telethon Labor Day Weekend
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... ... August 18, 2017 , ... ... a highly specialized asset-light logistics provider of complex transport solutions for mission-critical ... to purchase Unitrans International Corporation, a division of Roadrunner Transportation Systems, Inc. ...
(Date:8/18/2017)... ... August 18, 2017 , ... The Dawn Johnson Insurance Group, a Missouri-based insurance ... to generate community support for efforts to educate the local population on cancer realities ... types of cancer. , Each day in America, roughly 4,600 new cases of ...
(Date:8/18/2017)... ... August 18, 2017 , ... The Brian Gifford Agency, an Indiana-based firm providing ... support of Campagna Academy in a charity drive to provide for at-risk children and ... Indiana,” Campagna Academy is a nonprofit organization that has offered critical programs to at-risk ...
(Date:8/18/2017)... ... August 18, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh in ... veil on false teachings pertaining to the mother of the Savior whom the world calls ... far different picture of the role of this historical woman. , “The world bows, ...
(Date:8/18/2017)... ... 18, 2017 , ... “Dangerous Inheritance”: a mystery about saving the family farm. ... from Southwest Nebraska where she was raised on a farm. As Diane wrote ... fictional, but the friendships and mantra of ‘neighbors helping neighbors’ have always been a ...
Breaking Medicine News(10 mins):
(Date:8/4/2017)... -- The search for test results that can be ... long been the goal of healthcare providers and the ... largest meeting of lab professionals and IVD firms this ... Kalorama Information.  The firm said scores of companies with ... and software were at the American Association for Clinical ...
(Date:8/2/2017)... Fenita J. Caldwell is ... Lifetime Professional in the Field of Healthcare. Caldwell ... Pharmaceuticals, AG. Her skills and areas of expertise ... Fenita ... experience as a highly successful sales specialist in ...
(Date:8/2/2017)... Aug. 2, 2017 CaryRx, a next-generation full-service pharmacy, ... service for patients in the Washington D.C. ... pharmacy by providing delivery of medications through the convenience of ... delivery or delivered within one hour to any location in ... to bring this invaluable service to Washington D.C. ...
Breaking Medicine Technology: