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A short and sweet diagnosis for cancer?
Date:7/9/2008

dable for early diagnosis.

In order to detect differences between cancerous and normal cells, the scientists are developing a robotic technique to analyse the sugars. "Sugars are removed from the proteins and then broken down into very small components using enzymes. These fragments can be individually characterised leading to the formation of a 'fingerprint' for each sugar we analyse," Professor Rudd explains. "By comparing the fingerprints of sugars from serum or individual proteins from cancer patients with those of disease-free people, we can find sugars which differ slightly between the two - these are the ones that are being tested as potential biomarkers. We are also refining a statistical analysis program which will enable more detailed examination of the data. As our method is high-throughput, we hope to be able to identify a large number of markers which can be taken forward for further testing and then clinical trials, leading to their potential use in both diagnosis and monitoring of cancer progression."


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Contact: Holly Astley
hma25@cam.ac.uk
44-779-285-5259
Society for Experimental Biology
Source:Eurekalert  

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