Navigation Links
A rare association: Non-islet cell tumor hypoglycemia
Date:6/17/2008

Non-islet cell tumor hypoglycemia (NICTH) is a rare association between spontaneous hypoglycemia and tumors derived from tissues other than the pancreatic islets. It was initially associated with abdominal soft tissue sarcomas, although other tumor types have been described.

The pathogenesis of hypoglycemia in NICTH may involve a variety of mechanisms, including excessive consumption of glucose by what is typically a large tumor; inadequate production of counterregulatory hormones, such as growth hormone or cortisol; or ectopic or abnormal secretion of insulin or insulin-like growth factor-2 (IGF-II) and IGF-binding proteins. This last mechanism seems to be the most frequent and best characterized in patients with typical NICTH. Insulin secretion by the non-beta-cell tumor is, however, extremely rare and most cases published are secondary to secretion of an incompletely processed IGF-II by the tumor (big IGF-II), which acts as an insulin-like factor in the insulin receptors, causing hypoglycemia

A research team led by Dr. Robert Diaz and his team from Spain have written an article to be published on March 28, 2008 in the World Journal of Gastroenterology. A 74-year-old patient with advanced sigmoid cancer, who suffered recurrent bouts of fasting hypoglycemia presented to them. The diagnostic work-up finally revealed the ectopic production of insulin by the tumor. The possible simultaneous presence of a pancreatic insulin-secreting primary tumor (insulinoma) was ruled out by different laboratory and imaging tests.


'/>"/>

Contact: Jing Zhu
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. Grocery Manufacturers Association: US Food & Drug Administration and European Food Safety Authority Affirm Safety of Certified Food Dyes
2. Grocery Manufacturers Association: Canadian Risk Assessment Reaffirms Safety of Bisphenol A (BPA) for Adults and Children
3. Texas Health Care Association: New Report on Long Term Care Workforce Spotlights Need to Boost Texas Medicaid Rates
4. AUDIO from Medialink and the National Lipid Association: Whats Your Triglycer-IQ?
5. A new weapon for attacking tumor invasion and metastasis
6. Ability to track stem cells in tumors could advance cancer treatments
7. Primary tumors can drive the growth of distant cancers
8. Primary Tumors Fuel Growth of Cancer Cells
9. Targeted Anticancer Drugs - In Vitro Assessment and Non-Invasive Imaging of Patient and Tumor Status Will Determine Clinical and Commercial Success
10. Cancer-killing viruses influence tumor blood-vessel growth
11. Solid tumor cells not killed by radiation and chemotherapy become stronger
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... , ... October 13, 2017 , ... The American Board ... become its next President and Chief Executive Officer, succeeding Dr. James C. Puffer upon ... beginning July 1, 2018 until Dr. Puffer’s retirement at the end of 2018. Upon ...
(Date:10/13/2017)... EDWARDSVILLE, Ill. (PRWEB) , ... ... ... University Edwardsville School of Pharmacy (SOP) alumni Hannah Randall, PharmD ‘17, and ... educated healthcare professionals on guideline updates for the primary prevention of cardiovascular ...
(Date:10/13/2017)... OBISPO, Calif. (PRWEB) , ... October 13, 2017 , ... ... or dementia. However, many long-term care insurance companies have a waiver for care if ... the 90-day elimination period, when the family pays for care, is often waived, so ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th ... Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, ... The fun run is geared towards children of all ages; it is a non-competitive, ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a ... has been awarded a contract by the Center for Medicare and Medicaid Services ... accelerate the enterprise use of Agile methodologies in a consistent and high value ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... , Oct. 12, 2017   Divoti USA ... Jewelry up to the standard of the latest FDA requirements, which ... 2017). Anyone in need of Medical ID jewelry such ... Alert Jewelry are engraved in terms of the new ... Divoti offers ...
(Date:10/11/2017)... Calif. , Oct. 11, 2017  BioPharmX Corporation ... scientific team that developed an innovative way to use ... of the delivery of new drugs. ... Fall Clinical Dermatology Conference will show how researchers from ... Hospital, Harvard Medical School used a suite of imaging ...
(Date:10/11/2017)... 2017  True Health, a leader in integrated ... during National Breast Cancer Awareness month to educate ... Research recently published ... more than 10 million American women are at ... or BRCA2 and have not had testing. These mutations ...
Breaking Medicine Technology: