Navigation Links
A patient's own skin cells may one day treat multiple diseases
Date:8/4/2011

erative properties as human embryonic stem cells, but they are derived in a lab from adult cells, such as skin cells, by inducing or forcing them to express specific genes that are normally dormant in that type of cell. In theory, a person's skin cells could be induced to make neurons that produce the neurotransmitter dopamine, for example, and be delivered to brain regions where it is lacking in patients with Parkinson's disease. Similarly, cells could be induced to regenerate heart muscle and blood vessels after a heart attack, or neurons following a spinal cord injury. Many labs at UC Davis, including the Knoepfler lab, are producing and studying human iPSCs.

One advantage cited for iPSCs over stem cells derived from embryos is that problems of rejection due to immunological differences between the donor (the embryo) and the patient would be eliminated, because the iPSCs would be derived from each individual patient. A recent study using iPSCs in mice found that tissue rejection may, in fact, occur in some cases. However, Knoepfler believes that particular study was conducted in the context of tumors, which tend to be highly immunogenic and not be applicable for human use. While the ability of human iPSCs to escape immune attention must be investigated further, Knoepfler says that iPSCs remain an attractive potential avenue for stem cell-based medicine, in addition to embryonic stem cells.

Another concern with using either iPSCs or embryonic stem cells is that cells with the ability to turn into many different cell types may grow out of control, producing cancerous tumors. Knoepfler points out those studies involved implanting large numbers of undifferentiated stem cells into mice that were treated with immunosuppressant drugs to reject transplants, making the conditions ideal for cancers to arise. This scenario, he argues, is unlikely to be applicable when treating humans for actual diseases. In such cases, the stem cells would be induced to
'/>"/>

Contact: Charles Casey
charles.casey@ucdmc.ucdavis.edu
916-734-9048
University of California - Davis Health System
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. High-risk stroke patients more likely to get follow-up care after motivational talk
2. Study: Inexpensive method detects ALK rearrangement in lung cancer patients
3. Statins May Help Heart in Some Young Stroke Patients
4. Spiritual retreat can lower depression, raise hope in heart patients
5. UM School of Medicine finds that mobile phone technology helps patients manage diabetes
6. Hospice improves care for dementia patients and their families
7. Best post-transplant drug regimen identified for patients with new kidneys
8. PATH B -- a comprehensive support program for patients diagnosed with chronic hepatitis B
9. 1 in 3 Nose Job Patients Has a Mental Illness: Study
10. New imaging technique captures brain activity in patients with chronic low back pain
11. Drug shown to improve sight for patients with inherited blindness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... (PRWEB) September 02, 2014 Cloud Medical ... of “Cloud Based” Medical Practice Business Operations solutions and ... of Digital Cyber Security solutions for all industries announced ... on the trading floor of the CME in Chicago ... DeLaGarza stated that we are very proud of the ...
(Date:9/2/2014)... NY (PRWEB) September 02, 2014 The ... new blood thinners is growing at a rapid pace, ... to mount in courts around the U.S., Bernstein Liebhard ... American Journal of Medicine, within a year of its ... prescribed Xarelto as warfarin, a blood thinner that has ...
(Date:9/2/2014)... 2014 The Wm. Jennings Bryan Dorn Veterans ... town hall meeting for Veterans and their families on September ... fair to provide Veterans with valuable healthcare and benefit information,” ... will provide a forum where we can gather important input ... outreach fair will be held 4:45 p.m. to 5:45 p.m. ...
(Date:9/2/2014)... September 02, 2014 On August 30, ... website titled “Why You Should Wash Your Face ... of the global population breathes air considered polluted by ... pollution lodge in the skin’s pores destroying its natural ... to free radicals that may cause cell damage, redness, ...
(Date:9/2/2014)... 2014 (HealthDay News) -- Complications are rare among ... a new study indicates. However, the researchers ... with a slightly higher risk for certain complications ... more than 18,000 breast cancer patients who had ... with breast reconstruction and were followed for 30 ...
Breaking Medicine News(10 mins):Health News:Cloud Medical Doctor Software Corporation's CEO Interviewed by the Price Futures Group 2Health News:Cloud Medical Doctor Software Corporation's CEO Interviewed by the Price Futures Group 3Health News:Xarelto Lawsuit News: Bernstein Liebhard LLP Comments on Growing Use of Xarelto in Spite of Mounting Product Liability Litigation 2Health News:Xarelto Lawsuit News: Bernstein Liebhard LLP Comments on Growing Use of Xarelto in Spite of Mounting Product Liability Litigation 3Health News:Xarelto Lawsuit News: Bernstein Liebhard LLP Comments on Growing Use of Xarelto in Spite of Mounting Product Liability Litigation 4Health News:Simon Ourian, Kim Kardashian’s Doctor: Air Pollution May Be Aging Your Skin 2Health News:Complication Rates Low With Mastectomy, Breast Reconstruction: Study 2
... seen with cirrohosis but aren,t sensitive enough , , ... to detect esophageal bleeding in people with cirrhosis show ... researchers. , About 25 percent of patients with cirrhosis ... veins commonly seen with cirrhosis. Variceal bleeding can cause ...
... movement, serious complications can follow, experts note , , TUESDAY, ... identified a marker that might predict which pregnant women ... essentially a baby,s first bowel movement, excreted in the ... is considered a sign of fetal distress. A small ...
... London, New Delhi, and Singapore (6 May, 2008) ... manage patients with depression has challenged the rationale behind ... behavioural therapy (CBT) for milder depression. , According ... is a lack of evidence for CBT being more ...
... with state and local public health agencies for,Community ... The Community Coalitions Health,Institute (CCHI), a 501(c)(3) affiliate ... that it has received a five-year grant from ... improvement in,community health systems across the country. The ...
... WHAT: On national grassroots lobby day, Lance Armstrong to visit four ... * TUESDAY, MAY 13, 2008 WHERE: Tour of Ralph ... (RLC) and RLC Fifth Anniversary Celebration at the Marcus ... 1919 Madison Avenue (Entrance on 124th Street) ...
... WASHINGTON, May 6 The latest,"gaming for health" ... games (e.g., a "disease" being unleashed inadvertently,on the ... videogames,used to train emergency medical personnel -- will ... event at 1 p.m. EDT Thursday,(May 8, 2008)., ...
Cached Medicine News:Health News:Noninvasive Procedures Show Promise for Esophageal Bleeding 2Health News:Doctors Discover Marker for Meconium Passage During Delivery 2Health News:Antidepressants do work in depression while evidence for CBT is poorer say experts 2Health News:Antidepressants do work in depression while evidence for CBT is poorer say experts 3Health News:NBCH's Community Coalitions Health Institute Receives CDC Grant 2Health News:Lance Armstrong Marks 5th Annual LIVESTRONG(TM) Day with Nationwide Fly-Around 2Health News:Video Gaming for Health: Major New Trends to Be Discussed as National Conference Gets Underway 2
(Date:9/2/2014)... 2, 2014  Numotion is pleased to announce the appointment ... Directors. Mark is a 30-year retired veteran ... across the organization and was a GE Company Officer since ... spent many years running business units within GE Healthcare, with ... Americas. "We are delighted to welcome Mark ...
(Date:9/2/2014)... 2014  On July 31, the Food and Drug ... is moving forward to regulate laboratory-developed tests (LDTs). The ... throughout the U.S. will need to comply with a ... laboratories may subscribe to the strategy to simply sit ... in place, it,s widely acknowledged that failure to answer ...
(Date:9/2/2014)... YORK , Sept. 2, 2014 ... is available in its catalogue: ... http://www.reportlinker.com/p02353210/Asia-Pacific-Infusion-Therapy-Device-Market.html Abstract: ... infusion therapy devices included volumetric infusion pumps, syringe ... needleless connectors and stopcocks. These categories are segmented ...
Breaking Medicine Technology:FDA Tells Congress It Intends to Regulate LDTs! Web Conference to Provide Straight Talk on Essential Steps Clinical Laboratories and Pathology Groups Will Need to Take to Comply 2FDA Tells Congress It Intends to Regulate LDTs! Web Conference to Provide Straight Talk on Essential Steps Clinical Laboratories and Pathology Groups Will Need to Take to Comply 3Asia-Pacific Infusion Therapy Device Market 2Asia-Pacific Infusion Therapy Device Market 3Asia-Pacific Infusion Therapy Device Market 4Asia-Pacific Infusion Therapy Device Market 5Asia-Pacific Infusion Therapy Device Market 6Asia-Pacific Infusion Therapy Device Market 7Asia-Pacific Infusion Therapy Device Market 8Asia-Pacific Infusion Therapy Device Market 9Asia-Pacific Infusion Therapy Device Market 10Asia-Pacific Infusion Therapy Device Market 11Asia-Pacific Infusion Therapy Device Market 12Asia-Pacific Infusion Therapy Device Market 13Asia-Pacific Infusion Therapy Device Market 14
... Society of Clinical Oncology,s ... Genitourinary Symposium -, ... (Nasdaq: DNDN ) today presented data,demonstrating the correlation of ... active cellular immunotherapy,for hormone-refractory prostate cancer, with overall survival. This ...
... Confirm the Benefit Avastin Brings to ... Patients With Breast Cancer., BASEL, ... in metastatic breast cancer investigating Avastin,(bevacizumab) in combination with docetaxel chemotherapy ... patients,live without their disease advancing., The findings come from the ...
Cached Medicine Technology:Dendreon Presents Data Correlating the Cumulative Potency of PROVENGE(R) to Overall Survival 2Dendreon Presents Data Correlating the Cumulative Potency of PROVENGE(R) to Overall Survival 3Dendreon Presents Data Correlating the Cumulative Potency of PROVENGE(R) to Overall Survival 4Second Phase III Study of Avastin in 1st Line Metastatic Breast Cancer Meets its Primary Endpoint 2Second Phase III Study of Avastin in 1st Line Metastatic Breast Cancer Meets its Primary Endpoint 3
The Triage® Parasite Panel is an enzyme immunoassay used for the detection of antigens specific for Giardia lamblia, Entamoeba histolytica/dispar and Cryptosporidium parvum in fresh or freshly fr...
... Urostym™ provides the most current ... including urinary and fecal incontinence. ... easily providing complete patient information ... Customer testimonials have proven Urostym™ ...
... affordable path to Sonesta flexibility. Three ... back adjustments. Packaged with basic accessories, ... of Sonesta add-ons, allowing you to ... needs; complete Sonesta flexibility at an ...
The Triage Drugs of Abuse Panel is the leading rapid drug screen used by U.S. hospitals. The Triage Drugs of Abuse Panel is a small, handheld urine test that provides qualitative results for up to n...
Medicine Products: