Navigation Links
A patient's own skin cells may one day treat multiple diseases
Date:8/4/2011

(SACRAMENTO, Calif.) The possibility of developing stem cells from a patient's own skin and using them to treat conditions as diverse as Parkinson's disease, Alzheimer's disease and cancer has generated tremendous excitement in the stem cell research community in recent years. Such therapies would avoid the controversial need for using stem cells derived from human embryos, and in theory, also bypass immunological problems inherent in using cells from one person to treat another.

However, in the nearly five years since the first article describing the development of stem cells derived from adult cells so-called induced pluripotent stem cells (iPSCs) unique problems inherent in their use have surfaced and even their immunological safety has been called into question.

According to Paul S. Knoepfler, UC Davis associate professor of cell biology and human anatomy, finding such obstacles in such a new and novel approach is not surprising and should not dissuade investigators from actively pursuing this avenue of research. A roadmap for finding solutions to the problems identified with iPSCs, written by Knoepfler and Bonnie Barrilleaux, a postdoctoral fellow working in Knoepfler's laboratory, is available online and will be published in the Aug. 5 issue of the journal Cell Stem Cell. Their perspective, "Inducing iPSCs to escape the dish," suggests research strategies to advance the field more rapidly toward applications for human diseases.

"iPSCs offer the potential to treat many diseases as an alternative or adjuvant therapy to drugs or surgery," said Knoepfler, who also is a faculty member of the UC Davis Genome Center and UC Davis Cancer Center. "Problems that have been identified with their use likely can be overcome, allowing iPSCs to jump from the laboratory dish to patients who could benefit from them."

iPSCs were first produced in 2006 from mouse cells and in 2007 from human cells. They have many of the same regen
'/>"/>

Contact: Charles Casey
charles.casey@ucdmc.ucdavis.edu
916-734-9048
University of California - Davis Health System
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related medicine news :

1. High-risk stroke patients more likely to get follow-up care after motivational talk
2. Study: Inexpensive method detects ALK rearrangement in lung cancer patients
3. Statins May Help Heart in Some Young Stroke Patients
4. Spiritual retreat can lower depression, raise hope in heart patients
5. UM School of Medicine finds that mobile phone technology helps patients manage diabetes
6. Hospice improves care for dementia patients and their families
7. Best post-transplant drug regimen identified for patients with new kidneys
8. PATH B -- a comprehensive support program for patients diagnosed with chronic hepatitis B
9. 1 in 3 Nose Job Patients Has a Mental Illness: Study
10. New imaging technique captures brain activity in patients with chronic low back pain
11. Drug shown to improve sight for patients with inherited blindness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2013)... Many orthodontists have thought about moving ... that cloud is. Most people would naturally assume ... provide their cloud service and support would own and ... they're selling, they'd be wrong. Cloud providers lease ... redundant facility that houses servers and related equipment to ...
(Date:5/25/2013)... BC (PRWEB) May 25, 2013 According ... the most beautiful and powerful women that ever lived. ... felt by some of the most powerful men in ... many beauty remedies to keep her skin glowing and ... made with bees- wax, maringa oil and cyprus grass. ...
(Date:5/25/2013)... Angeles, CA (PRWEB) May 25, 2013 The ... both its effectiveness and results. This is due to the ... breathable adhesive patches. Slim weight patch offers an extra 2 ... weight loss, fitness goals and get the body you desire ... Weight Patch Official Website , With Slim weight patch ...
(Date:5/25/2013)... 25, 2013 Prairie Living at ... hosting an American Red Cross Blood Drive from 1:30 ... community, which is located at 955 Villa Ct. in ... those on Medicaid, who need some help to maintain ... Life," says Andrea Arview Frey, Director of Marketing for ...
(Date:5/25/2013)... Mexico, DF (PRWEB) May 25, 2013 ... in sanscrit: "knowledge or wisdom of life". While a medical ... and the transformation of consciousness. Its fundamental philosophy is that ... with our environment. In order to re-establish optimal health, one ... then adopt a life style which brings us back into ...
Breaking Medicine News(10 mins):Health News:Cirrus Ortho Launches Cloud Computing for Orthodontic Industry That is Unlike Any Other 2Health News:The Cleopatra Lift - A New Non Surgical Option to Aging Offered by Vancouver Physician 2Health News:The Cleopatra Lift - A New Non Surgical Option to Aging Offered by Vancouver Physician 3Health News:Slim Weight Patch Advanced Weight Loss System Offers Extra Two Month Supply and Membership for Maximum Weight Loss 2Health News:Carbondale Affordable Assisted Living Community to Host Red Cross Blood Drive 2Health News:Fundamentos de Ayurveda in Mexico (Ayurvedic Principles) Offered by Escuela de Ayurveda de California 2
... of Illinois at Chicago College of Nursing has received a ... they transition to the end of life. , The ... of care for people of all ages facing death -- ... a $2.4 million grant from the National Institute of Nursing ...
... Robert Klaus, President and CEO of,Chicago-based Oral ... Advocacy Award from the Friends of the National ... Klaus,s contributions on behalf of oral health have ... Peter Anas,Executive Director, NIDCR. "He has approached oral ...
... new dental plan services for members, ROCKVILLE, ... /,Denex, provider of comprehensive dental plans and administration, ... division of the,nation,s leading integrated health plan provider. ... network access and,call center support to Kaiser Permanente ...
... (Dec. 13, 2007) -- A new study by a ... message for the elderly: It,s not too late to ... you,ve had an unhealthy lifestyle in the past! , ... of Clinical Nutrition, the report surveyed scientific literature and ...
... In addition to allowing us to see, the mammalian eye ... prime example of this is the timing of the sleep/wake ... the circadian pacemaker in the hypothalamus. , In a ... have identified two totally blind humans whose non-visual responses to ...
... Dec. 13 The Centers for Disease,Control ... the Association,for Professionals in Infection Control and ... transmission of,healthcare-associated infection (HAI) data from existing ... Safety Network (NHSN).,The vendor-neutral solution enables hospitals ...
Cached Medicine News:Health News:New UIC center to study end-of-life transition 2Health News:New UIC center to study end-of-life transition 3Health News:Oral Health America's Robert Klaus Honored for Outstanding Public Advocacy 2Health News:Message to the elderly: It's never too late to prevent illness! 2Health News:Blind humans lacking rods and cones retain normal responses to non-visual effects of light 2Health News:Blind humans lacking rods and cones retain normal responses to non-visual effects of light 3Health News:CDC Uses New Technical Approach to Enable Hospital Reporting of Healthcare-Associated Infections 2
(Date:5/23/2013)... May 23, 2013 More than half of ... benefit from chemotherapy and still have excellent outcomes. To ... one of the largest sources of online consumer information ... interactive Facebook page provide recently diagnosed women with information ... avoid chemotherapy. "We anticipate these innovative social ...
(Date:5/23/2013)... 2013  Texas, premier physician associations today announced the ... tools they need to provide demonstrably better and more ... marketplace. "I am confident the Physician Services ... Stephen L. Brotherton , MD, president ... doctors are determined to make health care ...
(Date:5/23/2013)... 2013  Ameritox, the nation,s leader in pain ... Inc. to become part of its Urine Drug ... costs and improve the clinical outcomes for injured ... benefit manager in the workers, compensation industry, has ... pain management strategy for several years. By establishing ...
Breaking Medicine Technology:Agendia Launches Social Media Campaigns to Help Breast Cancer Patients with Chemotherapy Decisions 2Agendia Launches Social Media Campaigns to Help Breast Cancer Patients with Chemotherapy Decisions 3TMA Launches Physician Services Organization for Patient Care 2TMA Launches Physician Services Organization for Patient Care 3TMA Launches Physician Services Organization for Patient Care 4Ameritox Joins with Progressive Medical in Urine Drug Monitoring Network to Help Improve Care of Injured Workers 2Ameritox Joins with Progressive Medical in Urine Drug Monitoring Network to Help Improve Care of Injured Workers 3
... total ergonomic solution and best value ... feather touch action and ultra lightweight ... Stress-free tip ejection with long, lever ... volume identification, Accepts universal tips or ...
... pro Electronic Pipette is ideal for all ... easy-to-follow display, ergonomically-placed operating buttons, and various ... pipetting and diluting make this a lab ... of a manual pipette without any adverse ...
... Pipette is ideal for all liquid handling ... ergonomically-placed operating buttons, and various dispensing techniques ... diluting make this a lab favorite. It ... manual pipette without any adverse effects on ...
Inquire...
Medicine Products: