Navigation Links
A patient's own skin cells may one day treat multiple diseases
Date:8/4/2011

(SACRAMENTO, Calif.) The possibility of developing stem cells from a patient's own skin and using them to treat conditions as diverse as Parkinson's disease, Alzheimer's disease and cancer has generated tremendous excitement in the stem cell research community in recent years. Such therapies would avoid the controversial need for using stem cells derived from human embryos, and in theory, also bypass immunological problems inherent in using cells from one person to treat another.

However, in the nearly five years since the first article describing the development of stem cells derived from adult cells so-called induced pluripotent stem cells (iPSCs) unique problems inherent in their use have surfaced and even their immunological safety has been called into question.

According to Paul S. Knoepfler, UC Davis associate professor of cell biology and human anatomy, finding such obstacles in such a new and novel approach is not surprising and should not dissuade investigators from actively pursuing this avenue of research. A roadmap for finding solutions to the problems identified with iPSCs, written by Knoepfler and Bonnie Barrilleaux, a postdoctoral fellow working in Knoepfler's laboratory, is available online and will be published in the Aug. 5 issue of the journal Cell Stem Cell. Their perspective, "Inducing iPSCs to escape the dish," suggests research strategies to advance the field more rapidly toward applications for human diseases.

"iPSCs offer the potential to treat many diseases as an alternative or adjuvant therapy to drugs or surgery," said Knoepfler, who also is a faculty member of the UC Davis Genome Center and UC Davis Cancer Center. "Problems that have been identified with their use likely can be overcome, allowing iPSCs to jump from the laboratory dish to patients who could benefit from them."

iPSCs were first produced in 2006 from mouse cells and in 2007 from human cells. They have many of the same regen
'/>"/>

Contact: Charles Casey
charles.casey@ucdmc.ucdavis.edu
916-734-9048
University of California - Davis Health System
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. High-risk stroke patients more likely to get follow-up care after motivational talk
2. Study: Inexpensive method detects ALK rearrangement in lung cancer patients
3. Statins May Help Heart in Some Young Stroke Patients
4. Spiritual retreat can lower depression, raise hope in heart patients
5. UM School of Medicine finds that mobile phone technology helps patients manage diabetes
6. Hospice improves care for dementia patients and their families
7. Best post-transplant drug regimen identified for patients with new kidneys
8. PATH B -- a comprehensive support program for patients diagnosed with chronic hepatitis B
9. 1 in 3 Nose Job Patients Has a Mental Illness: Study
10. New imaging technique captures brain activity in patients with chronic low back pain
11. Drug shown to improve sight for patients with inherited blindness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/26/2015)... (PRWEB) March 26, 2015 Visiting ... celebrate their 18th annual gala fundraiser, Lighting the Way, ... 6:30 p.m. at The Madison Hotel in Morristown, NJ. ... live entertainment by renowned musician Rio Clemente, delightful cuisine, ... Pat and Dave Hertzel. Additionally, two prestigious awards will ...
(Date:3/26/2015)... 26, 2015 The Life Support ... to Hyperbaric Medicine” course, which is accredited by ... and the National Board of Diving & Hyperbaric ... course 4 times a year at several of ... tri-state region; registration is available on-line at: ...
(Date:3/26/2015)... 2015 On March 5, 2015, Portland ... out for the season with a torn Achilles tendon ... Trail Blazers were competing against Dallas, and was confirmed ... Izzy Silva, M.D., who has treated many professional athletes, ... it could be prevented. , "Part of the ...
(Date:3/26/2015)... NY (PRWEB) March 26, 2015 Volunteers ... raise awareness of Parkinson’s disease and funds to support ... to Ease the Burden – Find the Cure. ... and will take place in more than 20 locations ... Island, New Jersey, San Antonio, Minnesota, Seattle, St. Louis, ...
(Date:3/26/2015)... CRN International took the podium this week at ... achievement of jobseekers from five statewide locations as part ... , The program, called Platform to Employment and being ... the Connecticut Department of Labor, takes active steps to ... them at appropriate companies. CRN, a 40-year-old radio marketing ...
Breaking Medicine News(10 mins):Health News:Morristown VNA Fundraiser to Honor Distinguished Community Members 2Health News:The Life Support Technologies Group (LST) Conducted its 30th Accredited “Introduction to Hyperbaric Medicine” Course for Health Care Professionals 2Health News:The Life Support Technologies Group (LST) Conducted its 30th Accredited “Introduction to Hyperbaric Medicine” Course for Health Care Professionals 3Health News:The Life Support Technologies Group (LST) Conducted its 30th Accredited “Introduction to Hyperbaric Medicine” Course for Health Care Professionals 4Health News:Sports Medicine Specialist Weighs In on Wesley Matthew’s Significant Tendon Injury; Can it be Prevented? 2Health News:Sports Medicine Specialist Weighs In on Wesley Matthew’s Significant Tendon Injury; Can it be Prevented? 3Health News:Sports Medicine Specialist Weighs In on Wesley Matthew’s Significant Tendon Injury; Can it be Prevented? 4Health News:American Parkinson Disease Association 2015 Optimism Walk Season Launches Nationwide 2Health News:CRN International Shows Support For Groundbreaking Connecticut Program To Aid The Unemployed 2
... business response to global economic and social challengesNEW YORK, April ... aimed at creating new partnerships with governments, NGOs and small ... on Creating Shared Value in New York ... and the Mission of ...
... Inc. (OTC Bulletin Board: PLCSF) announced today that it expects ... the first quarter ended March 31, 2009 before the market ... host a conference call to discuss those results at 11:00 ... joined via telephone by dialing (866) 825-1708 or (617) 213-8060 ...
... 27 Cornerstone Therapeutics Inc. (NasdaqCM: CRTX), a specialty ... for respiratory disorders, today announced that it will host ... May 7, 2009, to discuss its financial results for ... also provide an update on the Company,s strategy, operations ...
... TERI, Inc., a national leader ... with autism and other developmental disabilities, today announced ... Quality Plans(TM) for families and caregivers of people ... the TERI-led International Association for Life Quality ( ...
... Group at Frost & Sullivan is pleased ... the Pharmaceutical CRM Market to be held on Tuesday, ... http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO )2008 has ushered in a variety of ... is adopting a cautious approach, delaying and re-evaluating technology ...
... to highlight advances for chronic condition; third FDA-approved drug to come ... ... Each new treatment that becomes available is a step forward for ... National Fibromyalgia Association (NFA), which is observing Fibromyalgia Awareness ...
Cached Medicine News:Health News:Nestle Launches Major Initiatives in Nutrition, Water and Rural Development 2Health News:Nestle Launches Major Initiatives in Nutrition, Water and Rural Development 3Health News:Nestle Launches Major Initiatives in Nutrition, Water and Rural Development 4Health News:Cornerstone Therapeutics to Host First Quarter 2009 Conference Call 2Health News:Cornerstone Therapeutics to Host First Quarter 2009 Conference Call 3Health News:Cornerstone Therapeutics to Host First Quarter 2009 Conference Call 4Health News:TERI Offers Comprehensive Life Quality Plans to Families, Caregivers of People with Developmental Disabilities 2Health News:Frost & Sullivan: The Pharmaceutical Customer Relationship Management Market - What are the Emerging Trends and Opportunities? 2Health News:Frost & Sullivan: The Pharmaceutical Customer Relationship Management Market - What are the Emerging Trends and Opportunities? 3Health News:Treatment Options Increase For Millions with Fibromyalgia 2Health News:Treatment Options Increase For Millions with Fibromyalgia 3
(Date:3/26/2015)... , March 26, 2015  Merrimack ... that it will present preclinical and clinical ... the 2015 American Association for Cancer Research ... 2015 at the Pennsylvania Convention Center in Philadelphia. The presentations describe ... and nanoliposomal technology platforms, as well as ...
(Date:3/26/2015)... 26. März 2015 Finesse Solutions ... sich speziell an Innovatoren, Visionäre und Führungskräfte ... Die zweitägige Konferenz für geladene Gäste findet ... Hyatt Regency in Downtown San ... werden führende Akteure der Biowissenschaften die Zukunft ...
(Date:3/26/2015)... Calif. , March 26, 2015 ... Care Management (CCM) Physician, Patient and Pharmacy Portals, ... Modular EHR certification, which designates that the software ... the Stage 1 and Stage 2 Meaningful Use ... American Recovery and Reinvestment Act (ARRA). SPAC CCM ...
Breaking Medicine Technology:Merrimack to Highlight Extensive Oncology Pipeline at the 2015 American Association for Cancer Research Annual Meeting 2Merrimack to Highlight Extensive Oncology Pipeline at the 2015 American Association for Cancer Research Annual Meeting 3Finesse Solutions kündigt Cellworld 2015 an 2SPAC International's Chronic Care Management Physician, Patient and Pharmacy Portals Achieve ONC HIT 2014 Edition Modular EHR Certification from ICSA Labs 2SPAC International's Chronic Care Management Physician, Patient and Pharmacy Portals Achieve ONC HIT 2014 Edition Modular EHR Certification from ICSA Labs 3
... 17 Emdeon (NYSE: EM ), a leading provider ... it will participate in the Piper Jaffray Annual Health Care Conference ... York. , The "fireside chat", featuring Tracy Bahl, executive chairman, will ... A live audio webcast will be available in the Investors ...
... , NEW YORK, Nov. 17 WebMD Health Corp. (Nasdaq: ... participate at the 2009 Citi Investment Research Small and Mid Cap ... , Investors, analysts and the general public are invited to ... Internet. The broadcast can be accessed at www.wbmd.com ...
Cached Medicine Technology:
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: