Navigation Links
A patient who was diagnosed as IPN-B without hepatolithiasis?
Date:4/30/2008

Intraductal papillary neoplasm of the bile duct (IPN-B) is a neoplastic lesion preceding invasive intrahepatic cholangiocarcinoma (ICC) and is a new definition of a tumor with papillary growth in the intra- or extra-hepatic bile duct. The authors reported a case of IPN-B with interesting histopathological findings and emphasized that cholangiography is especially helpful for the diagnosis of bile duct dilatation due to the infiltration of carcinoma cells.

This case report, presented by a group led by Dr J Hayashi, is described in a research article to be published on March 14, 2008, in the World Journal of Gastroenterology.

This patient's laboratory data were within normal ranges and no solid mass was detected in her abdominal computed tomography (CT) scan or nuclear magnetic resonance imaging (MRI). However, endoscopic retrograde cholangiopancreatography (ERCP) demonstrated an obstruction of the right bile duct. ERCP is recommended to determine the presence and location of the suspected intraductal tumor before laparotomy. Intraoperative cholangiography showed stenosis of the intrahepatic bile duct in the anterior inferior segment (B5) and narrowness of the intrahepatic bile duct in the anterior superior segment (B8), so they strongly suspected intrahepatic cholangiocarcinoma (ICC). Histologically, surgically resected liver specimens, which are determined to be without tumor mass by macroscopic observation, showed intraductal papillary proliferation with fibrovascular cores and intraductal spreading of carcinoma in situ throughout a considerable area, especially in bile ductules around the peripheral small portal area. Furthermore, the immunohistochemical profile of the tumor (MUC5AC+/CK7+) was compatible with an intraductal papillary neoplasm of the bile duct (IPN-B). Consequently, this case was diagnosed as IPN-B with spreading CIS, stage I (pT1, pN0, P0, H1, M0). They reported a case of IPN-B with interesting histopathological findings and emphasized that cholangiography is especially helpful for the diagnosis of bile duct dilatation due to the infiltration of carcinoma cells.


'/>"/>

Contact: Jing Zhu
wjg@wjgnet.com
0086-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Related medicine news :

1. Preoperative assessment of cancer patients enables early diagnosis, treatment of lymphedema
2. Medicare costs estimated to top $21.1 billion for 5 years of care for elderly cancer patients
3. Transitioning patients with pediatric disease to adulthood
4. Systematic Review of Patient-Reported Outcomes (PROs) Can Reduce Cost of Cancer Care
5. Rural Maryland Hospitals Form Unprecedented Collaborative to Improve Patient Care
6. Kidney Care Community Applauds National Taxpayers Unions Endorsement of Medicare Reforms to Extend Patient Private Health Insurance Coverage; Calls Proposal Common Sense Coverage Reform
7. SynergEyes Hybrid Contact Lenses Provide a Vision Solution for Post-LASIK Patients
8. FDA Examines Quality of Life for LASIK Patients
9. Clinical Symptoms Enough to Switch Drug Regimens for HIV Patients
10. UCB Launches CIMplicity(TM) Program to Enhance Treatment Support for Cimzia(R) (certolizumab pegol) Patients and Caregivers
11. Study shows positive findings in treating patients with advanced hepatitis C
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... , ... February 08, 2016 , ... ... IN metro area, has selected the latest beneficiary of their ongoing community enrichment ... to preventing bullying in area schools. Donations are now being accepted at: ...
(Date:2/8/2016)... Pekin, IL (PRWEB) , ... February 08, 2016 ... ... debilitating conditions that co-occur frequently. While a significant number of women and men ... PTSD, not the trauma itself, that best predicts the development of an eating ...
(Date:2/8/2016)... ... 08, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating to a ... derived from a cluster of melanin when exposed to sunlight. Although most moles are ... lifetime of embarrassment. Historically, mole removal has involved a painful, often expensive ...
(Date:2/7/2016)... Clarkston, Metamora, Michigan (PRWEB) , ... February 07, ... ... correct pelvic organ prolapse with the latest techniques and the most minimally invasive ... for pelvic organ prolapse, particularly after menopause. Other risk factors include surgery to ...
(Date:2/6/2016)... San Rafael, CA (PRWEB) , ... February 06, 2016 , ... ... 2016 Youth Ultimate Coaching Conference (YUCC) . This event brings together top non-profit leaders, ... is “Gender Equity and Girls Ultimate”. Valerio Iani, Bay Area Disc Program Director of ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... Respiratory Devices - Medical Devices Pipeline ... sector report, " Respiratory Devices - Medical Devices ... Respiratory Devices currently in pipeline stage. The ... with comparative analysis of the products at various ... involved in the pipeline product development. It also ...
(Date:2/8/2016)... -- Aesthetic Devices - Medical Devices Pipeline Assessment, 2015 ... Devices - Medical Devices Pipeline Assessment, 2015" provides an ... This report is prepared using data sourced ... team of industry experts. *Note: Certain sections in ... the availability and relevance of data in relation to ...
(Date:2/8/2016)... Ohio , Feb. 8, 2016 ... introduce the PW Series Solvent Recycling Systems, specifically ... offers full integration with new and existing vapor ... integration produces consistently-fresh solvent through continuous recycling and ... --> --> Precision ...
Breaking Medicine Technology: