Navigation Links
A patient who was diagnosed as IPN-B without hepatolithiasis?
Date:4/30/2008

Intraductal papillary neoplasm of the bile duct (IPN-B) is a neoplastic lesion preceding invasive intrahepatic cholangiocarcinoma (ICC) and is a new definition of a tumor with papillary growth in the intra- or extra-hepatic bile duct. The authors reported a case of IPN-B with interesting histopathological findings and emphasized that cholangiography is especially helpful for the diagnosis of bile duct dilatation due to the infiltration of carcinoma cells.

This case report, presented by a group led by Dr J Hayashi, is described in a research article to be published on March 14, 2008, in the World Journal of Gastroenterology.

This patient's laboratory data were within normal ranges and no solid mass was detected in her abdominal computed tomography (CT) scan or nuclear magnetic resonance imaging (MRI). However, endoscopic retrograde cholangiopancreatography (ERCP) demonstrated an obstruction of the right bile duct. ERCP is recommended to determine the presence and location of the suspected intraductal tumor before laparotomy. Intraoperative cholangiography showed stenosis of the intrahepatic bile duct in the anterior inferior segment (B5) and narrowness of the intrahepatic bile duct in the anterior superior segment (B8), so they strongly suspected intrahepatic cholangiocarcinoma (ICC). Histologically, surgically resected liver specimens, which are determined to be without tumor mass by macroscopic observation, showed intraductal papillary proliferation with fibrovascular cores and intraductal spreading of carcinoma in situ throughout a considerable area, especially in bile ductules around the peripheral small portal area. Furthermore, the immunohistochemical profile of the tumor (MUC5AC+/CK7+) was compatible with an intraductal papillary neoplasm of the bile duct (IPN-B). Consequently, this case was diagnosed as IPN-B with spreading CIS, stage I (pT1, pN0, P0, H1, M0). They reported a case of IPN-B with interesting histopathological findings and emphasized that cholangiography is especially helpful for the diagnosis of bile duct dilatation due to the infiltration of carcinoma cells.


'/>"/>

Contact: Jing Zhu
wjg@wjgnet.com
0086-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Related medicine news :

1. Preoperative assessment of cancer patients enables early diagnosis, treatment of lymphedema
2. Medicare costs estimated to top $21.1 billion for 5 years of care for elderly cancer patients
3. Transitioning patients with pediatric disease to adulthood
4. Systematic Review of Patient-Reported Outcomes (PROs) Can Reduce Cost of Cancer Care
5. Rural Maryland Hospitals Form Unprecedented Collaborative to Improve Patient Care
6. Kidney Care Community Applauds National Taxpayers Unions Endorsement of Medicare Reforms to Extend Patient Private Health Insurance Coverage; Calls Proposal Common Sense Coverage Reform
7. SynergEyes Hybrid Contact Lenses Provide a Vision Solution for Post-LASIK Patients
8. FDA Examines Quality of Life for LASIK Patients
9. Clinical Symptoms Enough to Switch Drug Regimens for HIV Patients
10. UCB Launches CIMplicity(TM) Program to Enhance Treatment Support for Cimzia(R) (certolizumab pegol) Patients and Caregivers
11. Study shows positive findings in treating patients with advanced hepatitis C
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2017)... ... ... HYPERAMS, LLC announced it will perform the inventory liquidation of ... The sale began this week and the inventory is expected to sell quickly. ... medical accessories, including blood pressure cuffs, stethoscopes, CPR masks, as well as blank polos, ...
(Date:5/27/2017)... (PRWEB) , ... May 26, 2017 , ... A May ... who visit a doctor for colds or respiratory issues that are not responsive to ... time pressure on doctors may be largely responsible for the problem both in Canada ...
(Date:5/27/2017)... ... 2017 , ... Most us are familiar with the sound of occasional popping ... Osteoarthritis Initiative shows that certain people who experience consistent joint popping, grating and ... doctors the opportunity to treat patients before the problem becomes pronounced, potentially hedging off ...
(Date:5/26/2017)... ... May 26, 2017 , ... The ... educational seminar to focus on current legislative activity and the latest regulatory concerns ... 1 p.m. Sunday, Sept. 10, and will continue through Monday, Sept. 11, at ...
(Date:5/26/2017)... ... May 26, 2017 , ... ... is sharing bold recipes for Memorial Day entertaining that are sure to satisfy ... “Boar’s Head fresh sliced meats and cheeses featured in these refreshingly balanced recipes ...
Breaking Medicine News(10 mins):
(Date:5/4/2017)... May 4, 2017  A new tight-tolerance microextrusion ... other highly-engineered materials, is being launched by Natvar, ... been developed in recent years to service a ... surgical applications. More expensive materials such as glass ... tubing due to their ability to consistently hold ...
(Date:5/3/2017)... 3, 2017 A Catheterization Laboratory is ... healthcare facility. Commonly referred to as cath lab, ... diagnostic imaging technology to give physicians visual access ... these spaces, a team of physicians perform life-saving ... coronary intervention, congenital heart defect closure, stenotic heart ...
(Date:5/3/2017)... , May 3, 2017  Getinge, a leading ... to quality enhancement and cost efficiency within healthcare ... study of contemporary practice demonstrating that intra-aortic balloon ... for critically ill patients. The single-center, retrospective, observational ... large volume MEGA ® 50cc intra-aortic balloon ...
Breaking Medicine Technology: