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A pan-European study: Signs of motor disorders can appear years before disease manifestation
Date:5/22/2013

nifestations of this kind can be measured years before the disease is likely to become obvious."

The findings for the other two types of ataxia were less conclusive. "I assume that there are indications also for these types of the disease. However, this subgroup of participants was relatively small. It is therefore difficult to make statistically reliable statements about these subjects," says the Bonn-based researcher.

In his view, the study results testify to the modern-day view of neurodegenerative processes: "Neurodegeneration doesn't begin when the symptoms surface. Rather, it is a stealthy disease which starts developing years or even decades beforehand."

Klockgether believes that this gradual development offers certain opportunities: "If we intervened in this process by appropriate treatments and at a sufficiently early stage, it might be possible to slow down or even stop the disease process."

More investigations planned

The current results will be the basis for long-term investigations. A new series of tests with the same group of individuals has already started; further tests are scheduled every two years. The scientists intend to monitor the study participants for as long as possible.


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Contact: Marcus Neitzert
marcus.neitzert@dzne.de
49-228-433-02271
Helmholtz Association of German Research Centres
Source:Eurekalert

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