Navigation Links
A new understanding of why seizures occur with alcohol withdrawal
Date:10/17/2009

CHICAGO Epileptic seizures are the most dramatic and prominent aspect of the "alcohol withdrawal syndrome" that occurs when a person abruptly stops a long-term or chronic drinking habit. Researchers have shown that the flow of calcium ions into brain cells via voltage-gated calcium channels plays an important role in the generation of alcohol withdrawal seizures, because blocking this flow suppresses these seizures. But do the changes in calcium currents contribute to alcohol withdrawal seizures or are they a consequence of the seizures?

Using a careful analysis of correlations between the course of alcohol withdrawal seizures and the expression of calcium currents, Georgetown University Medical Center researchers found that the enhancement of total calcium current density in pre-clinical animal studies occur prior to the onset of alcohol withdrawal seizures. The research presented at 39th annual meeting of the Society for Neuroscience also shows that calcium currents remain enhanced during the period of seizure susceptibility, but return to control levels when the period of seizure susceptibility is over.

"These preliminary findings are the first to indicate that altered calcium channel activity contributes to the occurrence of alcohol withdrawal seizures," explains lead author, Prosper N'Gouemo, PhD, an assistant professor in the department of pediatrics at GUMC. "The next step in our research is to determine which types of voltage-gated calcium channels contribute to the enhanced current density that takes place before the onset of alcohol withdrawal seizures so a potential treatment can be developed."


'/>"/>

Contact: Karen Mallet
km463@georgetown.edu
215-514-9751
Georgetown University Medical Center
Source:Eurekalert

Page: 1

Related medicine news :

1. Informational handout key to giving parents a better understanding of CT radiation risks
2. Updated GOLD report presents new understandings in diagnosis, treatment and prevention of COPD
3. New understanding of basic units of memory
4. Optical scientist honored for understanding and improving vision
5. Increased Understanding Called for During November National Alzheimers Disease Awareness Month by Los Angeles Jewish Homes Medical Director
6. Understanding of Mammography Differs Among Races
7. Canadian Pacific and Mayo Clinic Build Understanding and Commit to Ongoing Dialogue
8. Understanding College Student Mental Health: The Psychological, Institutional and Legal Issues
9. OHSU Cancer Institute research discovery opens new window to understanding chronic myeloid leukemia
10. Understanding the have-knots: The role of stress in just about everything
11. Revolution in understanding of ion channel regulation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/4/2015)... (PRWEB) , ... September 04, 2015 , ... Yisrayl Hawkins, Pastor and Overseer at The ... says are prophetic details involving the Pope’s upcoming trip to the United States. , Yisrayl ... what his role with the Vatican and society is. Yisrayl also provides the meaning of ...
(Date:9/3/2015)... ... , ... AlignLife of Wauwatosa is excited to hold its annual ... and adults who don't have the ability to buy a jacket warm enough for ... Coat Drive to help those in need." , This is AlignLife's third annual Coat ...
(Date:9/3/2015)... , ... September 03, 2015 , ... ... , a privately held medical technology company that will bring low-cost cancer pre-screening ... worldwide. , Preora’s proprietary and automated technology platform detects and measures cellular ...
(Date:9/3/2015)... ... September 03, 2015 , ... The Beryl Institute ... 2016, to be held April 13-15 at Sheraton Hotel in Dallas, Texas. Patient ... the collective voices of healthcare leaders, staff, physicians, patients and families across the ...
(Date:9/3/2015)... ... September 03, 2015 , ... BedJet released a new version of its award ... Kickstarter. Today the BedJet v2 pre-order campaign blazed past the $1 million ... campaigns ever on crowdfunding giant Kickstarter. , Simple to use and beautifully designed, the ...
Breaking Medicine News(10 mins):Health News:Yisrayl Hawkins Writes Open Letter to Pope Francis In Light of Approaching U.S. Visit 2Health News:AlignLife is Helping to Keep the Community Warm This Winter 2Health News:Preora Diagnostics to Commercialize Cancer Pre-screening Tests 2Health News:Preora Diagnostics to Commercialize Cancer Pre-screening Tests 3Health News:Patient Experience Conference 2016 Program Announced by The Beryl Institute 2Health News:Patient Experience Conference 2016 Program Announced by The Beryl Institute 3Health News:BedJet Hits $1 million in Sales in 28 Days on Kickstarter after Shark Tank Rejection 2Health News:BedJet Hits $1 million in Sales in 28 Days on Kickstarter after Shark Tank Rejection 3
... ... sellers can now work with a RE/MAX agent who participates in the ... a donation to Susan G. Komen for the Cure when a home ... Cure™ sign riders on RE/MAX yard signs, is meant to raise money ...
... ... recovery planning, launched two new online tools to help small-to-medium businesses in the Greater Houston ... , ... 22, 2010 - X-ISS , experts in IT disaster recovery planning, launched two new ...
... blood glucose (sugar) was high during pregnancy are more likely ... diabeteseven after taking into consideration the children,s body weight, a ... The Endocrine Society,s 92nd Annual Meeting in San Diego. ... diabetes or gestational diabetes, or who have high blood sugar ...
... ... for cancer research in Los Angeles took place June 10-12 at Dodger Stadium and YAS-A-THON ... the largest single donor of ThinkCure Weekend. Talk about a home run! , ... (PRWEB) June 22, 2010 -- YAS,s founder ...
... , ... SeeMyRadiology.com, Accelarad’s online medical image cloud computing service, today announced the following organizations ... , ... Atlanta (PRWEB) June 22, 2010 -- SeeMyRadiology.com ( http://www.SeeMyRadiology.com ), Accelarad’s ...
... with the prestigious 2010 IEEE Medal for Innovations in ... implementation of the PET/CT scanner. Prof Townsend will ... Nutt, on 26 June 2010 at the IEEE Honors ... world,s largest professional association advancing technology for humanity. ...
Cached Medicine News:Health News:Susan G. Komen for the Cure and RE/MAX Launch Home for the Cure™ 2Health News:Susan G. Komen for the Cure and RE/MAX Launch Home for the Cure™ 3Health News:Susan G. Komen for the Cure and RE/MAX Launch Home for the Cure™ 4Health News:X-ISS Launches Free Online Disaster Recovery Planning Assessment Tools for Small Businesses 2Health News:Mothers' high blood sugar in pregnancy is linked to children's reduced insulin sensitivity 2Health News:YAS-A-THON for ThinkCure Hits it Out of the Park: $140,000 Raised, 270,000 Calories Burned! 2Health News:YAS-A-THON for ThinkCure Hits it Out of the Park: $140,000 Raised, 270,000 Calories Burned! 3Health News:Accelarad Announces Six New SeeMyRadiology.com Customers Seeking Fast, Secure and Innovative Medical Image Exchange Solution 2Health News:A*STAR scientist receives international award for innovation in healthcare technology 2
(Date:9/3/2015)... , Sept. 3, 2015 ... proprietary Modoo Fetus Monitoring Patch, a wearable medical device ... deliver fetal movement data, providing safety guidance for pregnant ... The device, which measures 4 centimeters ... and weighs a little more than an Apple earphone ...
(Date:9/3/2015)... , Sep. 03, 2015 ... addition of the "Diabetes Care Devices Market In ... Blood Glucose Meters, Continuous Glucose Monitors, Testing Strips, Lancets, ... 2020" report to their offering. The ... valued at USD 1.7 Billion in 2015 and is ...
(Date:9/3/2015)...  VirtualScopics, Inc. (NASDAQ: VSCP ), a ... today, they are collaborating with a large pharmaceutical ... study partnering with the Ministry of Health in ... up with a cardiac sonographer to acquire echocardiograms ... be used to identify children with rheumatic heart ...
Breaking Medicine Technology:Modoo to Debut at Kickstarter: First Device on the Market that Enables Continuous Monitoring of Fetal Heart Rate and Fetal Movement 2The BRIC Diabetes Care Devices Market is Estimated to Grow at a CAGR of 6.3% from 2015 to 2020, to Reach USD 2.3 Billion by 2020 2The BRIC Diabetes Care Devices Market is Estimated to Grow at a CAGR of 6.3% from 2015 to 2020, to Reach USD 2.3 Billion by 2020 3VirtualScopics, Inc. Collaborates with Large Pharmaceutical Company on a Philanthropic, Epidemiology Study in Africa 2VirtualScopics, Inc. Collaborates with Large Pharmaceutical Company on a Philanthropic, Epidemiology Study in Africa 3VirtualScopics, Inc. Collaborates with Large Pharmaceutical Company on a Philanthropic, Epidemiology Study in Africa 4
... N.C., Dec. 21, 2010 bioMerieux, a world leader in ... results of a survey demonstrating that most critical care nurses ... improve outcomes for sepsis patients. The survey, conducted at the ... that while the vast majority of nurses expressed the need ...
... – ERT (Nasdaq: ERES ), a global ... and medical device industries, today confirmed that the effective ... J. McKelvey, its President and CEO, is December 21, ... and Chief Scientific Officer, has also been elected by ...
Cached Medicine Technology:Critical Care Nurses Do Not Have Access to Tools They Need to Treat Sepsis 2Critical Care Nurses Do Not Have Access to Tools They Need to Treat Sepsis 3ERT Announces the Appointment of Joel Morganroth, MD as Interim CEO 2ERT Announces the Appointment of Joel Morganroth, MD as Interim CEO 3
CEMEX Fast Set is a solution for multiple indications and preferences. It is a self-contained delivery system in a convenient 70gm size....
... Techno-Aide provides the highest level ... highest quality lead protective eyewear. ... + tolerance allowed. Mfg supervised by ... All lens meet or exceed standards ...
This flexiable metal clip-on easily attaches to most frames and allows for excellent radiation protection. Not available with side shields or in prescription....
All New Ultra Pb Series Glasses...
Medicine Products: