Navigation Links
A new strategy normalizes blood sugars in diabetes
Date:3/28/2010

vere defect in the up-regulation of chaperones," says Ozcan. "But when we increase levels of free p85 in the liver of obese, severely diabetic mice, we see a significant increase in XBP1 activity and chaperone response and, consequently, improved glucose tolerance and reduced blood glucose levels."

When people are obese, the insulin signaling that normally increases free p85 is impaired, leading to more ER stress and more insulin resistance, ultimately leading to type 2 diabetes. But Ozcan thinks this vicious cycle can be circumvented through strategies that increase levels of free p85. His group is taking further steps to activate this novel pathway to create new treatment strategies for type 2 diabetes.


'/>"/>

Contact: Andrea Duggan
andrea.duggan@childrens.harvard.edu
617-919-3110
Children's Hospital Boston
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Novel Parkinson's Treatment Strategy Involves Cell Transplantation
2. Targeting leukemia cells gene addiction presents new strategy for treatment
3. New Cancer-Fighting Strategy Focuses On Signaling Molecules
4. New strategy produces promising advance in cancer vaccines
5. Data Strategy Announces SurePath Services Offering for EMC Avamar
6. Keenan Chief Strategy Officer Selected to Join Editorial Board of Payers & Providers
7. SOKO Fitness & Spa Group Broadens Geographic Expansion Strategy
8. Governor Rendell Proposes Budget With No Tax Increase, More Money for Public Schools, Strategy for Jobs, Plan to Address Future Deficits
9. A Nutty Super Bowl Snacks Strategy Helps Keep Diets in Play
10. Medical Breakthrough: Drug Free Strategy Shows Promise for Reversing or Halting Osteoporosis for Michigan Men and Women
11. Health Reform Needs Enforceable National Workforce Strategy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... Hastings and Hastings, a law firm in Arizona ... of legal representation client review requests for slip and fall ... rise in the number of slip and fall related accidents ... Valley. With that said, a large number of injury victims ... law firm. Hastings and Hastings is a personal injury firm ...
(Date:1/22/2015)... LunaDress, with its top dressmaking technologies, has been a ... is showing its latest designs of wedding dresses and launching ... company’s CEO, all the fresh new products are designed for ... to 80% off. All the clothes from LunaDress follow up ...
(Date:1/22/2015)... 22, 2015 Padre Murphy's and Owner Tom ... Pro Player Health Alliance (PPHA). The PPHA's passion ... getting everyone, including NFL greats, treated for obstructive sleep apnea ... groups supporting the cause in the valley. The most recent ...
(Date:1/22/2015)... Blue Cross and Blue Shield of Minnesota (Blue Cross) wants ... “Live Fearless.” , The “Faces of Fearless” campaign ... how they or someone they know has faced a challenge, ... moment. By telling these types of stories through livefearlessmn.com, participants ...
(Date:1/22/2015)... A new white paper by The Beryl ... the long-term care environment as well as provides recommendations ... paper, “The Power of Person-Centeredness in Long-Term Care: A ... the patient, resident and family experience in long-term care ...
Breaking Medicine News(10 mins):Health News:Hastings and Hastings Reports a Record Number of Client Review Requests for Slip and Fall Accidents in 2014 2Health News:LunaDress Shows The Latest Styles Of Wedding Dresses In 2015 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 3Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3
... guidelines for the treatment of exacerbations in cystic fibrosis ... clinical practices. "This is the first such comprehensive ... exacerbation of cystic fibrosis," said Susanna McColley, M.D., head ... the Cystic Fibrosis Center at Children,s Memorial Hospital and ...
... surprising reversal of long-standing scientific belief, researchers at the Mayo ... brain is not the trigger that leads to buildup of ... inflammation helps clear the brain of these noxious amyloid plaques ... mice that are predisposed to the disorder, say the researchers ...
... prescriptions issued by GPs has been caused by a year ... drugs on a long-term basis, according to researchers from the ... printed edition of British Medical Journal ( BMJ ... number of new patients diagnosed with depression over 11 years, ...
... discard stored embryos, studies show , THURSDAY, Oct. 22 ... playing a key role in many couples, decisions about ... using assisted reproductive technology or whether they will discard ... , Among the new findings, presented this week at ...
... exposing healthy kids to those already sick with the H1N1 flu ... are doing all they can to avoid the swine flu, some ... , These are parents who are reportedly arranging swine flu "parties" ... healthy children can be exposed to the virus through kids who ...
... worldwide study could one day lead to new treatments ... worldwide study has clinched the case that the gene ... involved in Parkinson,s disease. , "For those of us ... come up with insights that are applicable to more ...
Cached Medicine News:Health News:New clinical guidelines for exacerbations in cystic fibrosis 2Health News:Manipulating brain inflammation may help clear brain of amyloid plaques, Mayo Clinic researchers say 2Health News:Manipulating brain inflammation may help clear brain of amyloid plaques, Mayo Clinic researchers say 3Health News:Money Woes Keeping Many Couples From Fertility Treatments 2Health News:Money Woes Keeping Many Couples From Fertility Treatments 3Health News:Swine Flu Parties? Send Your Regrets, Experts Say 2Health News:Gene Behind Gaucher Disease a Player in Parkinson's 2Health News:Gene Behind Gaucher Disease a Player in Parkinson's 3
(Date:1/23/2015)... , Jan. 23, 2015  Immune Therapeutics, Inc. today announced the ... the compounding, packaging and distributing of its naltrexone tablets.  The ... United States . KRS Global is ... tablets in various strengths for individual patients in response to ...
(Date:1/23/2015)... 2015  iMD Companies, Inc. (ICBU) has repositioned itself as a ... grab a foothold in the hydroponic, hemp and medical marijuana ... presence in the sector, and recently partnering with the Chippewa ... and medical marijuana, iMD is committing to bring its vision ...
(Date:1/23/2015)... , Jan. 23, 2015  Mallinckrodt plc (NYSE: ... has approved a share repurchase program. The open-ended authorization ... of Mallinckrodt plc ordinary shares. "Funding ... top priorities as we continue to pursue a range ...
Breaking Medicine Technology:Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 2Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 3Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 4iMD Companies Poised to Make Impact in Multi-Billion Dollar Medical Marijuana Sector With Recent Investments and Strategic Partnerships 2Mallinckrodt plc Announces Share Repurchase Program 2Mallinckrodt plc Announces Share Repurchase Program 3Mallinckrodt plc Announces Share Repurchase Program 4
... SAN DIEGO, Oct. 28 Neurocrine Biosciences, Inc. (Nasdaq: NBIX ... 30, 2009. For the third quarter of 2009, the Company reported ... with a net loss of $17.7 million, or $0.46 per share, ... September 30, 2009, the Company reported a net loss of $43.1 ...
... BATESVILLE, Ind., Oct. 28 Hill-Rom Holdings, Inc. (NYSE: ... and 2010 financial guidance on Wednesday, November 11, 2009. ... morning on Thursday, November 12, 2009 at 7:30 a.m. EST. ... Quarter Earnings and 2010 Financial Guidance release will be issued ...
Cached Medicine Technology:Neurocrine Biosciences Reports Third Quarter 2009 Results 2Neurocrine Biosciences Reports Third Quarter 2009 Results 3Neurocrine Biosciences Reports Third Quarter 2009 Results 4Neurocrine Biosciences Reports Third Quarter 2009 Results 5Neurocrine Biosciences Reports Third Quarter 2009 Results 6Neurocrine Biosciences Reports Third Quarter 2009 Results 7Neurocrine Biosciences Reports Third Quarter 2009 Results 8Hill-Rom Holdings, Inc. Invites You to Join Its Fiscal 2009 Fourth Quarter Earnings and 2010 Financial Guidance Webcast 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: