Navigation Links
A new strategy normalizes blood sugars in diabetes
Date:3/28/2010

vere defect in the up-regulation of chaperones," says Ozcan. "But when we increase levels of free p85 in the liver of obese, severely diabetic mice, we see a significant increase in XBP1 activity and chaperone response and, consequently, improved glucose tolerance and reduced blood glucose levels."

When people are obese, the insulin signaling that normally increases free p85 is impaired, leading to more ER stress and more insulin resistance, ultimately leading to type 2 diabetes. But Ozcan thinks this vicious cycle can be circumvented through strategies that increase levels of free p85. His group is taking further steps to activate this novel pathway to create new treatment strategies for type 2 diabetes.


'/>"/>

Contact: Andrea Duggan
andrea.duggan@childrens.harvard.edu
617-919-3110
Children's Hospital Boston
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Novel Parkinson's Treatment Strategy Involves Cell Transplantation
2. Targeting leukemia cells gene addiction presents new strategy for treatment
3. New Cancer-Fighting Strategy Focuses On Signaling Molecules
4. New strategy produces promising advance in cancer vaccines
5. Data Strategy Announces SurePath Services Offering for EMC Avamar
6. Keenan Chief Strategy Officer Selected to Join Editorial Board of Payers & Providers
7. SOKO Fitness & Spa Group Broadens Geographic Expansion Strategy
8. Governor Rendell Proposes Budget With No Tax Increase, More Money for Public Schools, Strategy for Jobs, Plan to Address Future Deficits
9. A Nutty Super Bowl Snacks Strategy Helps Keep Diets in Play
10. Medical Breakthrough: Drug Free Strategy Shows Promise for Reversing or Halting Osteoporosis for Michigan Men and Women
11. Health Reform Needs Enforceable National Workforce Strategy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2014)... professor in the new Institute for Biomedical Sciences ... $2.83 million federal grant to develop novel therapeutics ... grant from the Eunice Kennedy Shriver National Institute ... National Institutes of Health will support Plemper,s drug ... at least one distinct alternative compound. , Infections ...
(Date:4/24/2014)... to give than to receive at least if you,re ... , The study found that 15- and 16-year-olds who find ... family members, are less likely to become depressed than those ... the money for themselves. , The researchers detail their findings ... . , The study focused on the ventral striatum, a ...
(Date:4/24/2014)... pH1N1 virus caused the first flu pandemic in the ... and killed more than 50 people in the country. ... flu epidemics (winter/spring seasons). , Infections with influenza ... World Health Organization has recommended Tamiflu for treatment of ... this drug is that it targets viral proteins which ...
(Date:4/23/2014)... Moffitt Cancer Center researchers say clinical trials for ... leukemia (AML) are very promising. Patients treated with ... and daunorubicin, are showing better responses than patients ... , "Acute myeloid leukemia is an aggressive ... success, especially in older patients," explained Jeffrey Lancet, ...
(Date:4/23/2014)... to high-energy particles, simulating conditions astronauts would face on ... and slower reaction times, even when the radiation exposure ... impairments which affected a large subset, but far ... linked to protein changes in the brain, the scientists ... humans, suggest it may be possible to develop a ...
Breaking Medicine News(10 mins):Health News:Study: Altruistic adolescents less likely to become depressed 2Health News:Moffitt Cancer Center's phase 3 study may be game-changer for acute myeloid leukemia 2Health News:Some astronauts at risk for cognitive impairment, animal studies suggest 2Health News:Some astronauts at risk for cognitive impairment, animal studies suggest 3
... in the cereal category as they provide fibre beta glucan ... health-conscious consumers. So there is news to cheer now as ... called beta-glucan in their diets.,This variety of oats has been ... University (NDSU) scientists., ,Beta-glucan can help lower blood levels ...
... A new study has found that at high doses, ... result in liver damage, leading to significant health risks. ... University of Toronto, results of which can be found ... ,Previous studies have demonstrated the anti-oxidant effects of ...
... found out that retinal examination of a child, to determine the ... of abuse. // This was discussed in the American Academy of ... is a light sensitive tissue located behind the eye. Any rupture ... the result is bleeding or retinal hemorrhage. , A ...
... a molecular computer, which uses enzymes to perform calculations ... release of drugs.// ,Itamar Willner, who built ... Jerusalem in Israel, said the enzyme-powered computers could have ... future, be implanted into humans. ,The researchers ...
... California was slapped with four additional law suits, after the ... miserably. // ,Orange county Superior court has ... of patients who died just waiting for the transplants; the ... ,The liver transplant program transparent to gross mismanagement has to ...
... of doctors at the U.S. military prison in Guantanamo ... strike) through insertion of feeding tubes // through their ... who claim that such practices violate the fundamental principles ... are being subjected to harsh interrogations, targeted at extension ...
Cached Medicine News:Health News:Retinal Hemorrhage: No More a Sure Sign of Child Abuse 2Health News:Medical Ethics Violated By Prison Officials In Guantanamo Bay 2
(Date:1/15/2014)... Jan. 15, 2014  Research and Markets ( http://www.researchandmarkets.com/research/6k27gw/dental ) ... Market - Global Industry Analysis, Size, Share, Growth, Trends ... offering. (Logo: http://photos.prnewswire.com/prnh/20130307/600769 ... used on patients in order to treat dental impairments, ...
(Date:1/15/2014)... , Jan. 15, 2014  Celsion Corporation (the "Company") (NASDAQ: ... received commitments from institutional investors to purchase an aggregate ... in an at-the-market registered direct offering, led by a ... into definitive purchase agreements with these investors pursuant to ...
(Date:1/15/2014)... 15, 2014 BreedIT Corp (OTC: BRDT), ... distributor of highly sophisticated agro-breeding solutions for plant breeders ... the Company,s board of directors appointed chemistry and pharmaceutical ... new member of the board. From 1975 ...
Breaking Medicine Technology:Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 3Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 3BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 3
The INSIGNIA® pacing systems allow the physician to provide customized adaptive-rate pacing therapy to meet individual patient needs....
... less than thirty pounds, the EUB 405 ... quality. Compatible with a wide range of ... solution for a variety of clinical settings. ... easy to operate. It includes an alphanumeric ...
... The HI VISION 6500 ... offers advanced clinical imaging, enhanced ... flexibility, all in robust and ... a better clinical solution in ...
... The PENTAX FG-36UX provides a wide range ... It is also possible to obtain a clear ... Flow Mapping and Color Flow Angio. An accessory ... has improved. Those feature make it possible for ...
Medicine Products: