Navigation Links
A new radiotherapy technique significantly reduces irradiation of healthy tissue
Date:2/24/2012

This release is available in Spanish.

Researchers at the University of Granada and the university hospital Virgen de las Nieves in Granada have developed a new radiotherapy technique that is much less toxic than that traditionally used and only targets cancerous tissue.

This new protocol provides a less invasive but equally efficient cancer postoperative treatment for cases of cancer of the oral cavity and pharynx.

The study -conducted between 2005 and 2008- included 80 patients diagnosed with epidermoid cancer of the oral cavity and pharynx, who had undergone lymph node removal. The affected nodes were located by the surgeon during the intervention and classified into different risk levels. Classification allowed physicians to target the areas at a higher risk of recurrence. This way, neck areas at a lower risk of containing residual cancer cells were not irradiated. Researchers achieved both to minimize the side effects of radiotherapy, and to reduce treatment discontinuation, thus achieving the therapy to be more effective.

A Highly Toxic Treatment

Over 70% of oral and pharynx cancer treated with surgery require supplementary treatment with radiotherapy occasionally associated to chemotherapy, because of the high risk for recurrence and spread through the lymph nodes. Radiotherapy and chemotherapy are highly toxic, mainly due to the ulceration of the mucous membranes lining the oral cavity; toxicity leads may patients to stop the treatment, which significantly reduces the chances of cure.

By using the risk map obtained with the collaboration of the surgeon and the pathologist, an individualized treatment was designed and adapted to the specific risk level of recurrence in each neck area. The volume of tissue irradiated was significantly smaller than that usually irradiated with traditional techniques.

This trial was led by the radiation oncologist at the university hospital Virgen de las Nieves, Miguel Martnez Carrillo, and conducted in collaboration with the Services of Radiation Oncology, Medical Physics, Maxillofacial Surgery and Pathology of the university hospital Virgen de las Nieves, and the University of Granada Department of Radiology and Physical Medicine

After a three-year follow up, using this new technique, scientists achieved to reduce the volume of irradiated tissue in 44% of patients. By this new technique, irradiation of an average volume of 118 cc of tissue was avoided. A total of 95% of patients completed radiotherapy and presented significantly lower toxicity than patients treated with the traditional technique. Recurrence rates did not increase.

This study was coordinated by University of Granada professors Rosario del Moral vila and Jos Mariano Ruiz de Almodvar Rivera. The results of this study will be published in the next issue of the journal Radiation Oncology.


'/>"/>

Contact: Miguel Martnez Carrillo
martinezcarrillo.miguel@gmail.com
34-651-489-745
University of Granada
Source:Eurekalert

Related medicine news :

1. Advantages and motivations uncertain behind use of brachytherapy for breast cancer radiotherapy
2. Radiotherapy between or during chemotherapy cycles reduces risk of breast cancer recurrence
3. Combination of existing safety checks could greatly reduce radiotherapy errors
4. Sensitizing prostate cancer to radiotherapy
5. ASTRO publishes evidence-based guideline for thoracic radiotherapy
6. Jefferson doctors strengthen case for high-dose radiotherapy technique after radical prostatectomy
7. BUSM study shows chemoradiotherapy prior to surgery improves survival
8. ASTRO publishes palliative radiotherapy for bone metastases guideline
9. Stereotactic radiotherapy slows pancreatic cancer progression for inoperable patients
10. John Theurer Cancer Center first cancer center in N.J. to acquire new radiotherapy system
11. Well-tolerated radiotherapy provides longer life to patients with recurrent brain cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2017)... ... , ... Mediaplanet is proud to announce the launch of its newest edition ... readers on how to take care of all aspects of their skin. , On ... Dancing with the Stars professional, Witney Carson, shares her journey with the disease that ...
(Date:5/26/2017)... ... May 26, 2017 , ... The Radiology Business Management ... on current legislative activity and the latest regulatory concerns impacting RBMA members. The ... 10, and will continue through Monday, Sept. 11, at the Ritz-Carlton, Tysons Corner ...
(Date:5/26/2017)... ... May 26, 2017 , ... A new analysis of community health ... seniors are located in the Midwest. With the average cost of healthcare rising and ... concerned with both the quality and affordability of where they live. An annual 2017 ...
(Date:5/26/2017)... ... 26, 2017 , ... On May 24, the Congressional Budget Office (CBO) projected ... on May 4, would result in 23 million Americans losing their health insurance by ... Patient Protection and Affordable Care Act (ACA). , “It is clear from the ...
(Date:5/26/2017)... ... ... Silver Birch of Hammond, a new assisted lifestyle community, has welcomed its first ... at 5620 Sohl Avenue in Hammond, serves older adults who need some help to ... apartments. Each of the private apartments at Silver Birch features a kitchenette, spacious bathroom ...
Breaking Medicine News(10 mins):
(Date:5/23/2017)... PLEASANTON, Calif. , May 23, 2017 /PRNewswire/ ... world,s most innovative medical devices for pressure ulcer ... at the American Association of Critical Care Nurses, ... Houston May 22-25. The Leaf Patient ... designed specifically for the hospital environment.  The system ...
(Date:5/18/2017)... May 17, 2017  Bayer announced today that the ... be presented at the 53 rd Annual Meeting ... place June 2-6 in Chicago . ... span prostate, colorectal, liver and thyroid cancers, as well ... Phase II CHRONOS-1 trial of copanlisib in patients with ...
(Date:5/11/2017)...  Thornhill Research Inc. ( Toronto, Ontario, ... USD five-year, firm-fixed-priced, indefinite-quantity/indefinite-delivery contract by the U.S. ... (CCC) ( Ottawa, Ontario, Canada ) ... anesthesia to patients requiring emergency medical procedures in ... Corps have been a longtime partner with Thornhill ...
Breaking Medicine Technology: