Navigation Links
A new model can predict a woman's risk of breast, ovarian and womb cancer
Date:7/30/2013

The probability (absolute risk) of a woman developing breast, ovarian, and endometrial (womb) cancer can all be predicted using easily obtainable information on known risk factors for these cancers, according to a study by US researchers published in this week's PLOS Medicine.

Ruth Pfeiffer from the National Cancer Institute in Bethesda, USA and colleagues from institutions throughout the US, developed statistical models based on risk factors of these three common cancers that could help with clinical decision making.

The authors developed these models by using information from two large US studies that included white, non-Hispanic women aged over 50 years and by including commonly known risk factors, such as parity (the number of children a women delivered), body mass index (an indicator of the amount of body fat), use of oral contraceptives, and menopausal status and use of menopausal hormone therapy. The resulting models were able to predict individual women's risk of each cancer: for example, individual women's risk for endometrial cancer calculated using this model ranged from 0.5% to 29.5% over the next 20 years depending on their exposure to various risk factors.

The authors say: "These models predict absolute risks for breast, endometrial, and ovarian cancers from easily obtainable risk factors and may assist in clinical decision-making."

They add: "Limitations are the modest discriminatory ability of the breast and ovarian models and that these models may not generalize to women of other races."

In an accompanying Perspective, Lars Holmberg from Uppsala University Hospital in Sweden and Andrew Vickers from the Memorial Sloan-Kettering Cancer Center in New York (uninvolved in the study) support the focus of the model on helping with clinical-decision making and say: "Ruth Pfeiffer and colleagues present models for absolute risks and thereby avoid the common mistake of proclaiming a substantial relative risk as clinically relevant without considering the background risk."


'/>"/>

Contact: Fiona Godwin
fgodwin@plos.org
01-223-442-834
Public Library of Science
Source:Eurekalert

Related medicine news :

1. Actors, Models and Talent for Christ Announces Portland, Oregon Auditions for Up and Coming Talent of All Ages on August 10, 2013
2. Plume Paris Eyewear Introduces Captivating Frame Model Tours by Best Image Optical
3. New Upcoming National Audition Sites for Actors, Models and Talent for Christ in August 2013
4. Fit Body Boot Camp Franchise Announces “Thank You Veterans” Project, Giving Qualified Veterans the Opportunity to Buy Into Their Fitness Franchise Model for Just $1
5. Hollywood Actress, Jenn Gotzon Is Scout; Mentor and Acting Teacher for Actors; Models and Talent for Christ and Is Hosting Columbus Ohio Audition July 7, 2013
6. Jaco Booyens, Scout for Actors, Models and Talent for Christ (AMTC) Will Host Audition in Chicago, Saturday July 20th at the Crowne Plaza Chicago O'Hare
7. Metformin's Anti-Cancer Properties Clarified in an Obesity Cell Model of Pancreatic Cancer
8. Actors, Models & Talent for Christ Grad, Charles Michael Davis, Stars in Grey’s Anatomy, Another Stateside (post-production), and New TV Series The Originals
9. St. Louis MO Prepares for Actors, Models and Talent for Christ (AMTC) Auditions on Saturday, July 20th
10. New Compliance Division Provides a Sustainability Model for Small Businesses
11. Dan Keen Scouts for Actors, Models and Talent for Christ (AMTC) Audition in Nashville, Friday, July 26th
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... ... March 28, 2017 , ... Oily skin is a common and unwelcomed occurrence in people of ... a lot to offer to the discussion of dealing with excess skin oil. “Oily skin ... many home remedies that can help remove the oily shine while keeping the skin fresh ...
(Date:3/28/2017)... ... March 28, 2017 , ... “A Prophets Bones”: a thrilling adventure that reveals the ... , “There were things that his parents and teachers had asked of him that he ... he was going to defy the Almighty Creator. There were some who would have felt ...
(Date:3/27/2017)... FL (PRWEB) , ... March 27, 2017 , ... ... new patients for clear braces. People who want straight teeth without the extensive ... Invisalign® in Clearwater, FL, without acquiring a referral. A custom-designed series of ...
(Date:3/27/2017)... ... 2017 , ... Drs. Justin Kolnick, Kara Diamond, Randall Barton, Keith Hope and ... key role this treatment plays in protecting oral health, along with the benefits of ... who need a root canal in White Plains, NY or their second location in ...
(Date:3/27/2017)... (PRWEB) , ... March 27, 2017 , ... A study ... Buckingham MD, and his colleague, Sudeep Roy, MD, was recently published in the ... Electrocautery Efficacy in Rhytidectomy” details Drs. Buckingham and Roy’s study on the use of ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... 2017  Sanderling Ventures, portfolio company, Torax Medical, ... of Johnson & Johnson. Torax manufactures and markets the ... gastro-esophageal reflux disease (GERD). The LINK device is ... the procedure is currently available in the U.S. ... was founded by Sanderling Ventures, Mayo Medical Ventures ...
(Date:3/27/2017)... TEL AVIV, Israel , March 27, 2017 ... focused on oncology and immunology, announced today that AGI-134, an ... recently announced acquisition of Agalimmune Ltd., will be featured at ... Meeting in Washington, DC to ... ...
(Date:3/27/2017)... , March 27, 2017 The ... reach USD 16.0 billion by 2025, according to a ... prevalence of chronic diseases is anticipated to be responsible ... which thereby widens the scope for growth during the ... bariatric population, which is highly susceptible to chronic diseases, ...
Breaking Medicine Technology: