Navigation Links
A new model can predict a woman's risk of breast, ovarian and womb cancer
Date:7/30/2013

The probability (absolute risk) of a woman developing breast, ovarian, and endometrial (womb) cancer can all be predicted using easily obtainable information on known risk factors for these cancers, according to a study by US researchers published in this week's PLOS Medicine.

Ruth Pfeiffer from the National Cancer Institute in Bethesda, USA and colleagues from institutions throughout the US, developed statistical models based on risk factors of these three common cancers that could help with clinical decision making.

The authors developed these models by using information from two large US studies that included white, non-Hispanic women aged over 50 years and by including commonly known risk factors, such as parity (the number of children a women delivered), body mass index (an indicator of the amount of body fat), use of oral contraceptives, and menopausal status and use of menopausal hormone therapy. The resulting models were able to predict individual women's risk of each cancer: for example, individual women's risk for endometrial cancer calculated using this model ranged from 0.5% to 29.5% over the next 20 years depending on their exposure to various risk factors.

The authors say: "These models predict absolute risks for breast, endometrial, and ovarian cancers from easily obtainable risk factors and may assist in clinical decision-making."

They add: "Limitations are the modest discriminatory ability of the breast and ovarian models and that these models may not generalize to women of other races."

In an accompanying Perspective, Lars Holmberg from Uppsala University Hospital in Sweden and Andrew Vickers from the Memorial Sloan-Kettering Cancer Center in New York (uninvolved in the study) support the focus of the model on helping with clinical-decision making and say: "Ruth Pfeiffer and colleagues present models for absolute risks and thereby avoid the common mistake of proclaiming a substantial relative risk as clinically relevant without considering the background risk."


'/>"/>

Contact: Fiona Godwin
fgodwin@plos.org
01-223-442-834
Public Library of Science
Source:Eurekalert

Related medicine news :

1. Actors, Models and Talent for Christ Announces Portland, Oregon Auditions for Up and Coming Talent of All Ages on August 10, 2013
2. Plume Paris Eyewear Introduces Captivating Frame Model Tours by Best Image Optical
3. New Upcoming National Audition Sites for Actors, Models and Talent for Christ in August 2013
4. Fit Body Boot Camp Franchise Announces “Thank You Veterans” Project, Giving Qualified Veterans the Opportunity to Buy Into Their Fitness Franchise Model for Just $1
5. Hollywood Actress, Jenn Gotzon Is Scout; Mentor and Acting Teacher for Actors; Models and Talent for Christ and Is Hosting Columbus Ohio Audition July 7, 2013
6. Jaco Booyens, Scout for Actors, Models and Talent for Christ (AMTC) Will Host Audition in Chicago, Saturday July 20th at the Crowne Plaza Chicago O'Hare
7. Metformin's Anti-Cancer Properties Clarified in an Obesity Cell Model of Pancreatic Cancer
8. Actors, Models & Talent for Christ Grad, Charles Michael Davis, Stars in Grey’s Anatomy, Another Stateside (post-production), and New TV Series The Originals
9. St. Louis MO Prepares for Actors, Models and Talent for Christ (AMTC) Auditions on Saturday, July 20th
10. New Compliance Division Provides a Sustainability Model for Small Businesses
11. Dan Keen Scouts for Actors, Models and Talent for Christ (AMTC) Audition in Nashville, Friday, July 26th
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A Forever ... Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation ... as home to some of the world’s leading providers of cereal and other breakfast ...
(Date:6/25/2016)... D.C. (PRWEB) , ... June 25, 2016 , ... ... discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, ... their work on several important health care topics including advance care planning, healthcare ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic ... many turn to unhealthy avenues, such as drug or alcohol abuse, as a coping ... released tools for healthy coping following a traumatic event. , Trauma sufferers tend to ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... ... is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience ... Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)...   Pulmatrix, Inc ., (NASDAQ: PULM ... announced today that it was added to the Russell ... comprehensive set of U.S. and global equity indexes on ... milestone for Pulmatrix," said Chief Executive Officer Robert ... progress in developing drugs for crucial unmet medical needs, ...
(Date:6/24/2016)... 2016  Arkis BioSciences, a leading innovator in ... durable cerebrospinal fluid treatments, today announced it has ... is led by Innova Memphis, followed by Angel ... investors.  Arkis, new financing will accelerate the commercialization ... release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... Research and Markets has announced the addition of the ... report to their offering. ... failure, it replaces the function of kidneys by removing the ... the treatment helps to keep the patient body,s electrolytes such ... Increasing number of ESRD patients & substantial healthcare expenditure on ...
Breaking Medicine Technology: