Navigation Links
A new model can predict a woman's risk of breast, ovarian and womb cancer
Date:7/30/2013

The probability (absolute risk) of a woman developing breast, ovarian, and endometrial (womb) cancer can all be predicted using easily obtainable information on known risk factors for these cancers, according to a study by US researchers published in this week's PLOS Medicine.

Ruth Pfeiffer from the National Cancer Institute in Bethesda, USA and colleagues from institutions throughout the US, developed statistical models based on risk factors of these three common cancers that could help with clinical decision making.

The authors developed these models by using information from two large US studies that included white, non-Hispanic women aged over 50 years and by including commonly known risk factors, such as parity (the number of children a women delivered), body mass index (an indicator of the amount of body fat), use of oral contraceptives, and menopausal status and use of menopausal hormone therapy. The resulting models were able to predict individual women's risk of each cancer: for example, individual women's risk for endometrial cancer calculated using this model ranged from 0.5% to 29.5% over the next 20 years depending on their exposure to various risk factors.

The authors say: "These models predict absolute risks for breast, endometrial, and ovarian cancers from easily obtainable risk factors and may assist in clinical decision-making."

They add: "Limitations are the modest discriminatory ability of the breast and ovarian models and that these models may not generalize to women of other races."

In an accompanying Perspective, Lars Holmberg from Uppsala University Hospital in Sweden and Andrew Vickers from the Memorial Sloan-Kettering Cancer Center in New York (uninvolved in the study) support the focus of the model on helping with clinical-decision making and say: "Ruth Pfeiffer and colleagues present models for absolute risks and thereby avoid the common mistake of proclaiming a substantial relative risk as clinically relevant without considering the background risk."


'/>"/>

Contact: Fiona Godwin
fgodwin@plos.org
01-223-442-834
Public Library of Science
Source:Eurekalert

Related medicine news :

1. Actors, Models and Talent for Christ Announces Portland, Oregon Auditions for Up and Coming Talent of All Ages on August 10, 2013
2. Plume Paris Eyewear Introduces Captivating Frame Model Tours by Best Image Optical
3. New Upcoming National Audition Sites for Actors, Models and Talent for Christ in August 2013
4. Fit Body Boot Camp Franchise Announces “Thank You Veterans” Project, Giving Qualified Veterans the Opportunity to Buy Into Their Fitness Franchise Model for Just $1
5. Hollywood Actress, Jenn Gotzon Is Scout; Mentor and Acting Teacher for Actors; Models and Talent for Christ and Is Hosting Columbus Ohio Audition July 7, 2013
6. Jaco Booyens, Scout for Actors, Models and Talent for Christ (AMTC) Will Host Audition in Chicago, Saturday July 20th at the Crowne Plaza Chicago O'Hare
7. Metformin's Anti-Cancer Properties Clarified in an Obesity Cell Model of Pancreatic Cancer
8. Actors, Models & Talent for Christ Grad, Charles Michael Davis, Stars in Grey’s Anatomy, Another Stateside (post-production), and New TV Series The Originals
9. St. Louis MO Prepares for Actors, Models and Talent for Christ (AMTC) Auditions on Saturday, July 20th
10. New Compliance Division Provides a Sustainability Model for Small Businesses
11. Dan Keen Scouts for Actors, Models and Talent for Christ (AMTC) Audition in Nashville, Friday, July 26th
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/19/2017)... ... January 19, 2017 , ... Allegheny Health Network (AHN) officials today announced a ... the Network’s programs and services in the greater Pittsburgh region. Starting January 23, patients ... offered one for that same afternoon. , AHN is the first ...
(Date:1/19/2017)... (PRWEB) , ... January 19, 2017 , ... ... asset protection and financial planning services to communities throughout eastern Georgia, is embarking ... against heart disease. , Heart disease kills more Americans every year than anything ...
(Date:1/19/2017)... (PRWEB) , ... January 19, 2017 , ... ... owned insurance agency which serves Lawrenceville, New Jersey and the surrounding area, ... , Amyotrophic lateral sclerosis (ALS), more commonly known as Lou Gehrig's disease or ...
(Date:1/19/2017)... ... ... Attorney Robert “RC” Pate , founder of The Law Office of ... Kid Cancer foundation. Each year, 175,000 children are diagnosed with pediatric cancers. In 2006, ... of the critical funding gap for research into pediatric cancer research. From 2006 onwards, ...
(Date:1/19/2017)... ... January 19, 2017 , ... For the second ... Associates of Connecticut (RMACT) have earned “Top Doctor” awards. Dr. Mark Leondires, Dr. ... have each been chosen by their peers for the 2017 list based on ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... January 19, 2017 Incretin Mimetics/GLP-1 Agonists, SNDRIs, ... The global anti-obesity drugs market is expected ... of the forecast period and CAGR of 38.7% in the second ... at a CAGR of 32.8% from 2016 to 2027. The market ... and $24,063 million in 2027. ...
(Date:1/19/2017)... Calif. , Jan. 19, 2017 Accuray ... its CyberKnife® and TomoTherapy® Systems continue to set the ... received the highest composite overall user satisfaction rating among ... the Q4 2016 MD Buyline Market Intelligence Briefing™. The ... the highest composite ratings among industry peers for 11 ...
(Date:1/19/2017)... LONDON , January 19, 2017 ... Grothey ; European Oncology & Haematology, 2016;12(Suppl 2):3-8; ... ... http://photos.prnewswire.com/prnh/20151014/276718LOGO) Published recently in ... the peer-reviewed journal from touchONCOLOGY, an article by ...
Breaking Medicine Technology: