Navigation Links
A new method for bone-marrow-derived liver stem cells isolation and proliferation
Date:4/15/2009

Great interest has been aroused in the identification and isolation of liver stem cells from bone marrow cells. Several subsets of bone marrow cells have been found to have the potential to differentiate into hepatocytes, however, sorting based on immunological methods is difficult because of the complicated surface markers of the stem cells; furthermore, no report of successful passage has been published.

A research article to be published on April 7, 2009 in the World Journal of Gastroenterology addresses this question. The research team led by Dr. Cai and his colleagues from the Affiliated Foshan Hospital and the Second Affiliated Hospital of Sun Yat-sen University established a carefully designed culture system to isolate, proliferate and differentiate liver stem cells directly from bone marrow cells, and they were able to achieve six passages of the stem cells. The results suggest that BDLSCs can be purified and passaged.

The selecting culture system that contains cholestatic serum can purify BDLSCs directly from bone marrow cells, which provides an easy method to separate stem cells, by avoiding complicated immunological manipulation. The successful passage of the stem cells further verifies the proliferating ability of the cells, although the passage is limited, and further research will provide more experience.

In this study, the authors used their original method to retrieve the cells, which are possibly BDLSCs. Then, they used fluorescence-activated cell sorting to determine the cells' characteristics before and after differentiation. This is an interesting and potentially important study, which suggests that bone-marrow-derived cells can be stimulated to expand and then differentiate into hepatocyte-like cells, which can possibly be used to treat liver disease.


'/>"/>

Contact: Lin Tian
wjg@wjgnet.com
0086-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. NC State develops new test method to measure stored heat in firefighter suits
2. U study shows MRI-based method holds promise for predicting treatment outcomes in patients with AF
3. New, simple method identifies preterm infants at risk of eye disease
4. Patent pending for pain-free method of monitoring drug levels in transplant patients
5. Houstons Methodist Hospital to Pay U.S. More Than $9 Million to Resolve Allegations of Overcharging Medicare
6. U-M researchers idea jells into potential new disease-detection method
7. Raviv Method to Offer First U.S. Practitioner Training Course
8. Air Methods Announces Year 2008 Financial Results and Provides First Quarter 2009 Update
9. Clinical trial finds microbicide promising as HIV prevention method for women
10. Air Methods to Report Fourth Quarter and Fiscal Year 2008 Financial Results on Tuesday, March 10, 2009
11. Water method for unsedated colonoscopy; interval between prep and colonoscopy predicts prep quality
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... 2014 Avid collector Andrew Hawley, from Vintage ... Eagle Auditorium Seattle concert posters. The Doors were a smash ... that year. The Seattle Eagles Auditorium concert was held on ... return to Eagles Auditorium in November the same year. The ... and comes in three colors. The poster is a split ...
(Date:9/23/2014)... 2014 What: Rutgers Presbyterian Church, ... Side that embodies the inclusion and diversity of ... and the Ecological Crisis, a public lecture led ... Emerita of Old Testament at Louisville Presbyterian Seminary. ... that lends insight into current ecological problems, including ...
(Date:9/23/2014)... Oregon survey about an exercise DVD that adds short ... elementary school students found it had a high level ... clear advantages for overly sedentary educational programs. , Called ... the Healthy Youth Program of the Linus Pauling Institute ... Brain Breaks leads children in 5-7 minute segments of ...
(Date:9/23/2014)... (September 23, 2014) Both patients and healthcare ... computed tomography (CT) colonography greatly outweighs the potential ... precipitated by false-positive diagnoses, according to a new ... journal Radiology . , Diagnostic tests used ... organ. However, when screening for colorectal cancer with ...
(Date:9/23/2014)... September 23, 2014 The ... rhinitis (AR) is highly fragmented, with the ... formulations available, under different regulatory restrictions, with ... Europe has the most developed market, with ... allergen immunotherapy tablets (AITs) all being available. ...
Breaking Medicine News(10 mins):Health News:Inhabiting Eden: Christians, Scripture, and the Ecological Crisis – Public Lecture to Discuss Faith-Based Environmentalism 2Health News:'Brain Breaks' increase activity, educational performance in elementary schools 2Health News:'Brain Breaks' increase activity, educational performance in elementary schools 3Health News:Patients accept false-positives to achieve diagnostic sensitivity 2Health News:Patients accept false-positives to achieve diagnostic sensitivity 3Health News:Allergen extract Allergic Rhinitis Specific Immunotherapy Market to Grow $688.3m by 2018 Says a New Report Available at MarketOptimizer.org 2Health News:Allergen extract Allergic Rhinitis Specific Immunotherapy Market to Grow $688.3m by 2018 Says a New Report Available at MarketOptimizer.org 3Health News:Allergen extract Allergic Rhinitis Specific Immunotherapy Market to Grow $688.3m by 2018 Says a New Report Available at MarketOptimizer.org 4
... Increase for Small Business Owners at ... http://www.bluecrossca.com/click4biz , THOUSAND OAKS, Calif., ... fastest growing segments of California,s economy, however,many small business owners ... Blue Cross of California has just made it,easier for small ...
... vitamins and minerals does not seem to prevent the degenerative ... study published on bmj.com today. , Age related ... older people. It is caused by the progressive break down ... centre of the retina at the back of the eye. ...
... 8 Proposed,regulations that would govern who owns ... grants to for-profit organizations fail,to ensure affordable access ... for the research, the Foundation for Taxpayer and ... the people who have paid for the research ...
... Saturn, committed to health, fitness,and healthy living in communities ... health and fitness expo, held in conjunction with the ... Saturn Health and Fitness Expo, which runs Oct. 19-20 ... vendors,informational booths and groups that provide services to runners. ...
... 8 - The Washington,State Veterinary Medical Association awarded ... veterinarian with Olympia Pet,Emergency in Lacey. (Logo: ... his award in recognition of his dedication to,organized ... Washington,State University,s College of Veterinary Medicine, he has ...
... Help ... Owners Cope, SACRAMENTO, Calif., Oct. ... and language skills died last,month, his owner, scientist Irene Pepperberg, needed time ... it. Newspapers and web,sites printed his obituary and many people sent condolences. ...
Cached Medicine News:Health News:New Online Tool Makes Enrollment in Blue Cross of California Easier 2Health News:Antioxidants do not prevent degenerative eye disease 2Health News:Revised California Stem Cell Research Rules Fail to Ensure Affordable Access to Cures, Consumers Warn 2Health News:Saturn Shows Its Commitment to Health and Fitness by Becoming Expo Title Sponsor for The Detroit Free Press/Flagstar Marathon 2Health News:Lacey Veterinarian Awarded 2007 WSVMA Recent Graduate Award 2Health News:We Love Our Pets and Grieve When They Die 2Health News:We Love Our Pets and Grieve When They Die 3
(Date:9/23/2014)... -- Hill-Rom (NYSE: HRC ) today announced a ... WA ), the nation,s third largest not-for-profit health ... as Hill-Rom now becomes Providence Health,s sole-source provider of ... surface products. Providence Health is one ... operates 34 hospitals, 475 physician clinics, 22 long-term care ...
(Date:9/23/2014)... 2014  MEDIMETRIKS PHARMACEUTICALS today announced that ... have been elected to Medimetriks, Board of Directors ... who will serve on Medimetriks, Audit Committee, brings ... the Company.  Mr. Lary is currently Managing Director, ... institutional investment firm.  Mr. Lary is responsible for ...
(Date:9/23/2014)... , Sept. 23, 2014   COTA, Inc. ... planned $7 million Series A funding round led by ... COTA is the first big data platform designed by ... cost analysis for cancer care in support of healthcare,s ... used to expand development of the COTA platform, hire ...
Breaking Medicine Technology:Hill-Rom Announces Seven-Year, Sole-Source Contract with Providence Health 2Medimetriks Pharmaceuticals, Inc. Welcomes Independent Directors Andrew Lary and William Resnick to its Board of Directors 2COTA Closes $3.7M of Planned $7M Series A Funding Round to Transform Cancer Outcomes and Reimbursement 2COTA Closes $3.7M of Planned $7M Series A Funding Round to Transform Cancer Outcomes and Reimbursement 3COTA Closes $3.7M of Planned $7M Series A Funding Round to Transform Cancer Outcomes and Reimbursement 4
... March, 9, 2007-Active Biotech (ACTI.ST), today,announced new positive clinical ... treatment of prostate cancer. , By step-wise dose escalation, ... which corresponds to a doubling of the previously,reported maximum ... a step-wise intra-patient dose-escalation enables a dose,of 1 mg/day ...
... DENVER--(BUSINESS WIRE)--Mar 12, 2007 - Ceragenix Pharmaceuticals,Inc. ... and dermatology, today announced that a catheter,treated ... biofilm,formation in a 21 day study., In ... soaked daily in a phosphate-suffered solution along ...
Cached Medicine Technology:Positive Clinical Data for TASQ - Active Biotech's Novel Treatment,of Prostate Cancer 2Ceragenix Announces Ceragenins Virtually Prevent Catheter Biofilm,Formation in 21 Day Study 2Ceragenix Announces Ceragenins Virtually Prevent Catheter Biofilm,Formation in 21 Day Study 3
... Retinol binding Proetin (RBP) is small ... a complex with pre-albumin in blood but ... has been deliverd to the target cells. ... at the glomerulus and catabolized in the,renal ...
... is an enzyme immunoassay (EIA) kit for ... of the subclass of Anti-Neutrophil Cytoplasmic Antibodies ... as an aid in the diagnosis of ... associated with vasculitic disorders and glomerulonephritis (GN). ...
Anti-MPO ANCA EIA Auto-Immune Markers 013-MPO-96 Myeloperoxidase...
GBM -Ab EIA Auto-Immune Markers 013-GBM-96 Glomerular Basement Membrane...
Medicine Products: