A new light on the brains of people with borderline personalit... (nt and the money received. However in pe...)

A new light on the brains of people with borderline personality disorder

Date:8/7/2008

nt and the money received. However, in people with borderline personality disorder, that part of the brain responded only to sending the money not to the money received.

The scan casts a new light on the neurobiology of borderline personality disorder, said King-Casas, the study's lead author. Some day, he said, it could be used as a diagnostic tool or even a way to determine the effectiveness of a treatment.

"For the first time, to my knowledge, we have a specific brain association for people with a personality disorder," said Dr. Stuart Yudofsky, chair of the Menninger Department of Psychiatry and Behavioral Sciences at BCM. "It's new and different because it's not a lesion (or injury to the brain) but it is a difference in perceiving information that comes from an interaction." That is the area where people with borderline personality disorder have the most problem.

People with borderline personality disorder suffer from an inability to understand the actions of others. They frequently have unstable relationships, fly into rages inappropriately, or become depressed and cannot trust the actions and motives of other people.

"It's important that this biological signature has been identified," said King-Casas. "It's not just a matter of bad attitudes or a lack of will."

Yudofsky agrees that the finding my help eliminate the stigma associated with such disorders. The finding will help in three areas:

Diagnosis by giving a biologic measure that can be used to determine if a person has the problem.

Treatment using this brain-based difference to devise cognitive interventions or even medications that will affect the brain reactions.

Monitoring the effectiveness of treatment by determining how the brain's dysfunctional responses to the input from others change with treatment.

"We have great strength in the area of personality disorders through our relationship
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Contact: Dipali Pathak
pathak@bcm.edu
713-798-4710
Baylor College of Medicine
Source:Eurekalert

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