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A new definition for periprosthetic joint infection
Date:11/4/2011

(PHILADELPHIA) A rise in periprosthetic joint infection (PJI) rates has the orthopedic community moving to develop it's first-ever agreed upon definition and diagnostic criteria to help better treat patients.

The proposed criteria, published in the November issue of Clinical Orthopaedics and Related Research, was developed by a Musculoskeletal Infection Society working group led by Javad Parvizi, M.D., director of Research at the Rothman Institute at Jefferson. The group analyzed available research, much of which was conducted at Jefferson, to develop the new definition and criteria.

"Our aim was to develop a "gold standard" definition to serve as a roadmap for diagnosing patients with suspected PJI that could be universally adopted by the industry," said Dr. Parvizi.

PJI occurs in a replacement joint and is often found deep inside the joint prosthesis. It has become a major concern for the orthopedic community as antibiotic-resistance organisms have increased the prevalence of post-surgical periprosthetic infections. Deep periprosthetic joint infection is currently the most common indication for revision of total knee arthroplasty and the third most frequent indication for revision of total hip arthroplasty. The criteria will also be published in the December issue of the Journal of Arthroplasty.

The group's recommendations include sterile sampling of the periprosthetic tissue or fluid for the presence of virulent organisms, such as Staphylococcus aureus (S. aureus), the culprit in staph infections; and testing the blood serum surrounding the joint for e
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Contact: Lee-Ann Landis
leeann.landis@jefferson.edu
215-459-2092
Thomas Jefferson University
Source:Eurekalert

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