Navigation Links
A new approach to HIV vaccine development
Date:10/30/2012

To support their research for a vaccine against the HI-Virus, Prof. Dr. Klaus berla of the Faculty for Medicine at the Ruhr-Universitt Bochum and his research team will receive $2.3 million in funding within the next three years from the Bill & Melinda Gates Foundation. The scientists are part of the Collaboration for AIDS Vaccine Discovery (CAVD), which seeks to speed up the development of an HIV-vaccine through a rigorous exchange of information, methods and reagents. "The project rests upon our observation that certain immunological reactions seem to increase the risk of HIV-infection," Prof. berla said. "We want to avoid these kinds of harmful immune system responses while still creating protective antibodies."

Earlier study: HIV-vaccine increases risk of infection

Prior attempts to develop vaccines against HIV have not been successful. The preparation that was used in the Merck Pharmacy's so-called STEP study actually increases HIV susceptibility. "It is extraordinarily important to understand why the vaccine has this effect," berla said. "These findings could have an enormous impact on the development of future substances." By building on the findings of the STEP study, the research team plans to develop a new vaccine that will undergo in vivo testing.

T helper cells: HIV-proliferation vs. antibody production

Earlier studies have shown that certain antibodies against the envelope proteins of HIV could protect from HIV infection. Important for such antibody production are the CD4 T helper cells. Different kinds of these T helper cells recognize different pathogens in the body and signal other cells to create the appropriate antibodies in response to the invasive microorganisms. However, reactive CD4 T helper cells are also where HIV multiples particularly quickly. Therefore, if the number of HIV-responsive CD4 T helper cells increases as a result of the vaccine, the effect is simultaneously helpful and
'/>"/>

Contact: Klaus berla
virologie@ruhr-uni-bochum.de
49-234-322-3189
Ruhr-University Bochum
Source:Eurekalert

Page: 1 2

Related medicine news :

1. As painkiller overdoses mount, researchers outline effective approaches to curb epidemic
2. Informatics approach helps doctors, patients make sense of genome data
3. Triple-threat approach reduces life-threatening central line infections in children with cancer
4. A new approach for controlling the skyrocketing cost of health care
5. UCI microbiologists find new approach to fighting viral illnesses
6. NIH awards $7.8 million for innovative HIV vaccine approaches
7. Canada needs national approach to protect against drug shortages
8. A nonantibiotic approach for treating urinary tract infections
9. A hands-on approach to treating patients with pulmonary disease
10. GWU consensus report outlines new approaches for evaluating benefits and risks of obesity drugs
11. Scripps Florida scientists awarded nearly $1.5 million to develop new approaches to treat cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... 20, 2014 With a mere 19 ... Crist made a brief fundraising stop at the ... , Fresh from a debate last night with his ... stage for the first seven minutes because Crist had ... described the incident in one word: "weird." , Before ...
(Date:10/20/2014)... The Advocator Group, LLC is proud ... for Suicide Prevention’s (AFSP) Out of the Darkness walk ... that hosts hundreds of community walks throughout the country ... to help understand and prevent suicide through not only ... , The Advocator Group shares this passion for ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 Women’s health ... in Obstetrics & Gynecology of Columbus, Inc., A Division ... healthcare services to more than 100,000 patients annually. Dr. ... all ages and stages of a women’s life. She ... locations in Westerville and Dublin. , Dr. Murphy ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 hc1.com ... a secure cloud solution that enables healthcare organizations ... the ultimate healthcare-specific customer relationship management (“CRM”) solution. ... the unique needs of the healthcare industry, the ... for providers and patients by combining healthcare CRM, ...
(Date:10/20/2014)... Angeles, CA (PRWEB) October 20, 2014 ... fitness expertise, nutritional coaching, corporate wellness programming, authorship, international ... CPT, is excited to announce the release of the ... , After many years of coaching thousands of individuals ... nutrition tracking app that does not require calorie counting ...
Breaking Medicine News(10 mins):Health News:At Crist Fundraiser, Dan Newlin Says, "No More Robert Germans," Will Seek Changes to Florida Missing Persons Law 2Health News:At Crist Fundraiser, Dan Newlin Says, "No More Robert Germans," Will Seek Changes to Florida Missing Persons Law 3Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 2Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 3Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 2Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 3Health News:Healthcare Relationship Management (HRM) Leader hc1.com® Launches hc1® Quick Start™ 2Health News:JZ Fitness Nutrition App Launches on iTunes 2Health News:JZ Fitness Nutrition App Launches on iTunes 3
... March 19 Mirion Technologies, the,leading global provider ... protection industry, will showcase two new products at ... Beijing from,March 25th - 28th., Mirion,s Health ... Body Contamination Monitor. The TwoStep Exit monitor is ...
... March 19, 2008 Chronic fatigue syndrome ... debilitating diseases with no confirmed cause and limited ... literature study propose a simplified treatment process that ... these diseases. , Kent Holtorf, M.D., medical director ...
... SAN DIEGO, March 19 Cardium Therapeutics,(Amex: ... InnerCool Therapies announced today that,InnerCool has entered ... one of Australia,s leading medical device distributors ... agreement, Lifehealthcare will have,exclusive marketing, sales and ...
... March 19 Forest Laboratories, Inc.,(NYSE: FRX ) ... -,Scientific Affairs and President of the Forest Research Institute ... March 31, 2008., (Logo: http://www.newscom.com/cgi-bin/prnh/20001011/FORESTLOGO ), ... Officer of,Forest, stated: "The Board and I wish to ...
... Open Standard Data Management ... Systems for Company, ... of digital radiography (DR), PACS (Picture Archiving and,Communications System) and practice ... Dennis,Ballance, DVM, as division manager of the newly-formed Eklin Data Services,Division. ...
... Inc.,(Nasdaq: ABAX ), a medical products company ... Severson, CEO and,President, will present at Sidoti & ... Forum on Tuesday, March 25, 2008 at,11:00 a.m. ... Grand Hyatt in New York,City., About Abaxis, ...
Cached Medicine News:Health News:Mirion Technologies to Showcase New Product Offerings for the Nuclear Industry During 10th Annual China International Nuclear Industry Exhibition 2Health News:Data study suggests cortisol could alleviate for chronic fatigue syndrome and fibromyalgia 2Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 2Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 3Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 4Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 5Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 6Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 7Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 8Health News:Cardium's InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems 9Health News:Forest Laboratories Announces Resignation of Ivan Gergel, MD 2Health News:Eklin Medical Names Ballance Head of New Data Services Division 2Health News:Eklin Medical Names Ballance Head of New Data Services Division 3
(Date:10/22/2014)... 2014  CryoLife, Inc. (NYSE: CRY ), ... on cardiac and vascular surgery, announced today that ... Officer, has been elected to the Company,s Board of ... G. Anderson , Executive Chairman of CryoLife, stated, "Since joining ... an excellent leader who is well positioned to maximize ...
(Date:10/22/2014)... 2014 Oramed Pharmaceuticals Inc. ... pharmaceutical company focused on the development of oral ... results from its Phase IIa clinical trial of ... treat type 1 diabetes. The trial was conducted in ... a U.S. Food and Drug Administration (FDA) Investigational ...
(Date:10/22/2014)... , Oct. 21, 2014  Early symptoms of ... or unnoticed, but new technology, coupled with yearly, ... leading to earlier detection of eye diseases, including ... million Americans. If left untreated, these diseases can ... Recently, optometric researchers have deployed ...
Breaking Medicine Technology:Pat Mackin Joins CryoLife Board of Directors 2Pat Mackin Joins CryoLife Board of Directors 3Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 2Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 3Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 4Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 2Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 3
... ADA,s 2009 Convention -- When Shawnae Jebbia won the Miss ... fairytale career. She appeared at events throughout the world, worked ... Shawnae,s world unexpectedly changed when she was diagnosed with hearing ... she had a difficult time understanding and accepting the sudden ...
... Oct. 29 Mettler-Toledo International Inc. (NYSE: MTD ) today announced ... , Sales in local currency declined by 12% in ... negative currency impact. , Net earnings per diluted ... third quarter of 2008. Adjusted EPS was $1.36, a 6% ...
Cached Medicine Technology:Former Miss USA Shawnae Jebbia Shines with Siemens Pure 2Former Miss USA Shawnae Jebbia Shines with Siemens Pure 3Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 2Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 3Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 4Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 5Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 6Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 7Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 8Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 9Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 10Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 11Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 12Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 13
Symbia T, a TruePoint SPECTCT system, combines a dual-detector variable angle gamma camera with a CT scanner optimized for rapid, accurate attenuation correction of the nuclear data....
... analyzer and data management system ,RADIANCE ... traditional needs of data management systems (DMS), ... management of STAT analyzer systems., ,The RADIANCE ... solution for both STAT analyzers and hospital ...
... is a comprehensive IT solution that ... admission to follow-up. This scalable solution ... diagnostic tools from syngo Dynamics with ... longitudinal clinical repository that becomes a ...
... the AXIOM Artis dBC Magnetic Navigation ... navigation system equipped with digital flat ... is uniquely capable of improving the ... to facilitate increased efficiency and productivity ...
Medicine Products: