Navigation Links
A new agent for the treatment of patients with myelodysplastic syndrome; and more
Date:2/11/2008

A new agent for the treatment of patients with myelodysplastic syndrome

In a paper published this week in PLoS Medicine, Azra Raza and colleagues (University of Massachusetts) use gene expression profiling to identify a molecular signature that predicts response to lenalidomide in patients without chromosome 5q deletions. This suggests that these patients have a defect in erythroid differentiation.

In a related review article, Jerry Radich (Fred Hutchinson Cancer Research Center, Seattle, USA) reviews key research on the biology underlying treatment response in myelodysplasia, including Raza and colleagues' new study.

Citation: Ebert BL, Galili N, Tamayo P, Bosco J, Mak R, et al. (2008) An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndrome. PLoS Med 5(2): e35.

PLEASE ADD THE LINK TO THE PUBLISHED ARTICLE IN ONLINE

VERSIONS OF YOUR REPORT: http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pmed.0050035

PRESS-ONLY PREVIEW OF THE ARTICLE: http://www.plos.org/press/plme-05-02-raza.pdf

CONTACT:

Azra Raza
University of Massachusetts
Division of Hematology Oncology
Worcester, MA 01605
United States of America
araza@aptiumoncology.com


Related PLoS Medicine perspective article:

Citation: Radich J (2008) Solving the mystery of myelodysplasia. PLoS Med 5(2): e40

PLEASE ADD THE LINK TO THE PUBLISHED ARTICLE IN ONLINE

VERSIONS OF YOUR REPORT: http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pmed.0050040

PRESS-ONLY PREVIEW OF THE ARTICLE: http://www.plos.org/press/plme-05-02-radich.pdf

CONTACT:

Jerry Radich
Fred Hutchinson Cancer Research Center
Clinical Research Division
Seattle, Washington
United States of America
+1 206-667-4118
jradich@fhcrc.org


FROM THE PLoS MEDICINE MAGAZINE SECTION:

Salivating for knowledge: potential pharmacological agents in tick saliva

Joppe Hovius (University of Amsterdam) and colleagues review anticoagulant and immunosuppressive proteins present in tick saliva, and discuss how immunologically targeting such molecules could prevent transmission of tick-borne pathogens.

Citation: Hovius JWR, Levi M, Fikrig E (2008) Salivating for knowledge: Potential pharmacological agents in tick saliva. PLoS Med 5(2): e43.

PLEASE ADD THE LINK TO THE PUBLISHED ARTICLE IN ONLINE

VERSIONS OF YOUR REPORT: http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pmed.0050043

PRESS-ONLY PREVIEW OF THE ARTICLE: http://www.plos.org/press/plme-05-02-hovius.pdf

CONTACT:

Joppe Hovius
University of Amsterdam, AMC
Center for Experimental and Molecular Medicine
Meibergdreef 9
Amsterdam, Noord-Holland 1105 AZ
Netherlands
+31205666034
+31206977192 (fax)
j.w.hovius@amc.uva.nl


'/>"/>

Contact: Josh Eveleth
jeveleth@plos.org
415-624-1234
Public Library of Science
Source:Eurekalert

Related medicine news :

1. NuView Radiopharmaceuticals, Inc. Secures Exclusive Rights From Thomas Jefferson University for a Tumor-Specific Imaging Agent for the Diagnosis of Breast and Prostate Cancers
2. ABR-Affinity BioReagents Participates in the 2008 Fisher Scientific Supplier Expo in San Antonio, Texas
3. LiquidAgents Healthcare, LLC Awarded Accreditation from the Joint Commission
4. Insurance Agents Call for State Senate to Improve Californias Health Care Reform Compromise
5. Allergic reactions to gadolinium-based contrast agents are rare, study finds
6. Make 2008 the Year to Find an Insurance Agent Thats Right for You
7. Agent orange chemical, dioxin, attacks the mitochondria to cause cancer, says Penn research team
8. Pharmion and Methylgene Report Favorable Results for Phase 2 MGCD0103 Single- Agent Studies in Relapsed or Refractory Lymphomas at the 49th American Society of Hematology (ASH) Meeting
9. Germ-Fighting Inhaler Could Fend Off Bioterror Agents
10. National Patient Advocate Foundation (NPAF) Statement Regarding New FDA Label on Erythropoietin Stimulating Agents (ESAs)
11. Benepath Launches Exclusive Marketing Service for Health Insurance Agents and Agencies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2016)... ... 04, 2016 , ... Warren L. Smith M.D. , There is a new ... plagued people since the beginning of recorded medical history, and in spite of all ... not just a matter of inconvenience; bladder infections cost us billions of dollars annually ...
(Date:5/4/2016)... ... May 04, 2016 , ... With the stamp of approval from the ... May as National Cancer Research Month. According to the American Cancer Society (2016) ... predications of one in four Americans dying as a result. , With numbers as ...
(Date:5/4/2016)... (PRWEB) , ... May 04, 2016 , ... Fertility Centers ... at 535 Ocean Ave. Their new Maine Fertility Center provides convenient access to care ... Anne Rainville and her staff at Women’s Wellness Comprehensive Care in Portland,” said Fertility ...
(Date:5/4/2016)... ... ... Netc , a leading provider of barcode and RFID labels has ... Netc to continue to grow its label business, customer base and market share. , ... to print and label tape media on site and on an as needed basis. Many ...
(Date:5/3/2016)... ... May 04, 2016 , ... The National Association of Professional Women (NAPW) ... of the Year Circle. She is recognized with this prestigious distinction for leadership in ... than 850,000 members and over 200 operating Local Chapters. , “I’m pleased to welcome ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... , May 3, 2016   Diplomat Pharmacy, Inc. (NYSE: DPLO) announced today that it is ... a video of two patients who tell their personal story and encourage those at risk ... Meet Jacque: Hepatitis C ... ... Diplomat Specialty Pharmacy (PRNewsFoto/Diplomat Pharmacy, Inc.) ...
(Date:5/3/2016)... , May 3, 2016 ... Market Size, Share, Development, Growth and Demand Forecast to ... by Field Strength (High Field, Very High Field, Low ... (Brain, Head and Neck, Spine, Musculoskeletal, Vascular, Breast, Pelvic ... global magnetic resonance imaging (MRI) market was valued at ...
(Date:5/3/2016)... , May 3, 2016 ... INTP), a clinical-stage biopharmaceutical company, today announced the appointment ... and Regulatory Affairs. "Ms. Strauss-Levy has 15 ... and has established an outstanding track record, having supported ... and regulatory approval processes in the United ...
Breaking Medicine Technology: