Navigation Links
A lifespan-extending drug has limited effects on aging
Date:7/25/2013

The immunosuppressive drug rapamycin has been shown to increase longevity in mice even when treatment begins at an advanced age. It is unclear if the extension of life also correlates with prolonged health and vigor.

In the current issue of the Journal of Clinical Investigation, Dan Ehninger and colleagues at the German Center for Neurodegenrative Diseases evaluated age-associated characteristics in mice treated with rapamycin. They found that rapamycin improved memory and spatial learning, reduced thyroid follicle size, and reduced body fat in older mice. However, many of these same attributes were also improved in young mice treated with the drug, indicating an age-independent drug effect.

The prevalence of cancer, a common cause of mouse mortality, was also decreased in older treated mice. The authors did find that rapamycin treatment had no effect on several age related symptoms, including cardiovascular and liver function, loss of muscle mass, strength retention, or balance.

These data suggest that rapamycin treatment may increase lifespan through reduction of cancer rates, and the drug may be useful for relief of some age related conditions.

In the accompanying commentary, Arlan Richards of the University of Texas Health Science Center at San Antonio suggests that clinical trials to study the effect of rapamycin on age related neurodegenerative diseases of the elderly such as Alzheimer's disease should be considered.


'/>"/>

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related medicine news :

1. FiltersFast.com Promotes the Importance of Kitchen Range Hood Filters with a Limited One Day Offer
2. Classe Wines Offers 2008 Pinot Noir Domaine Jean-Michel Guillon Les Crais in Limited Quantity
3. 2000 Domaine Barat Chablis Premier Cru "Les Fourneaux" Available in Limited Quantity from Classe Wines
4. Lowering costs for higher-cost medicare patients through better outpatient care may be limited
5. Impact of iPad® on radiology residents daily clinical duties is limited, study suggests
6. PET-CT improves care of limited-stage small-cell lung cancer patients
7. Unique 2007 Pago de San Gabriel Zubiola Lote No.1 Edicion Limitada Still Available for Limited Time from Classe Wines
8. Garcinia Cambogia Select Dr. OZ Recommended Weight Loss Supplement Now Offers Extra Bottle on Every Purchase for Limited Time
9. Most Revolutionary Eye Care Product "Revitol Eye Cream" Now Available for Limited Time
10. Seattle Fitness Boot Camp Launches “Unlimited” Program
11. Acai Berry Select Safe & Effective for Weight Loss and Increased Energy. Get 3 Months Extra Supply for Limited Time
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/16/2017)... ... January 16, 2017 , ... Etymotic Research, ... GunSport•PRO® and EB15•LE® electronic earplugs at the NSSF SHOT Show on January 17-20, ... The SHOT Show is the shooting, hunting and outdoor trade show and conference ...
(Date:1/16/2017)... ... 16, 2017 , ... As New York’s fastest growing ophthalmic ... to their medical staff, according to eye surgeon, Jeffrey Martin, MD, FACS, Chief ... division of SightMD. Dr. Giamos will practice primarily out of SightMD’s Riverhead, Southampton, ...
(Date:1/16/2017)... ... ... are well-aware of the following facts at present:, Flu and ... no effect on keeping this particularly bad strain of the flu away , ... sniffling , These facts are well-known among the team at Woodard! About ...
(Date:1/16/2017)... (PRWEB) , ... January 16, 2017 , ... One thing ... only to treat, but to test for, as well. The money spent screening for ... year.(1) Doctors in the U.S. screen patients for cancer more than in any other ...
(Date:1/15/2017)... ... , ... In this role, Courtney will be responsible for developing new business ... friendly mark. This certification program was created by ASL and the nonprofit Asthma and ... suitable for the 60+ million people living in the U.S. with asthma and allergies. ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... , January 17, 2017 ... to potentially earn millions in revenue with the planned ... massive numbers of strokes with a simple test that ... Companies with latest developments in the markets today include: ... (NYSE: AZN ), Cancer Genetics, Inc. (NASDAQ: ...
(Date:1/17/2017)... 17, 2017 Catherine ... http://www.touchneurology.com/articles/tailored-temperature-management-neurocritical-care ...      (Logo: ... European Neurological Review , ... Amey reports that despite standard care, temperatures ...
(Date:1/17/2017)... 17, 2017  The pioneer in no-touch UV disinfection has ... Tru-D SmartUVC , short for "total room ultraviolet disinfection," was ... Terminal Room-Disinfection (BETR-D) study which was recently published in ... that Tru-D can cut transmission of four major superbugs by ... to market in 2007, we have been committed to innovation ...
Breaking Medicine Technology: