Navigation Links
A high-fat diet could promote the development of Alzheimer's
Date:10/28/2008

Quebec City, October 28, 2008A team of Universit Laval researchers has shown that the main neurological markers for Alzheimer's disease are exacerbated in the brains of mice fed a diet rich in animal fat and poor in omega-3s. Details of the studywhich suggests that diets typical of most industrialized countries promote the development of Alzheimer'sare outlined in the latest online edition of Neurobiology of Aging.

To demonstrate this, the team led by Frdric Calon used a type of transgenic mice that produce two proteins found in the brains of Alzheimer patientstau proteins, which prevent proper neuron functioning, and amyloid-beta, associated with the formation of senile plaques within the brains of afflicted patients.

The researchers fed transgenic and regular mice different diets for nine months, after which they compared the effects on the animals' brains.

The mice whose diet was poor in omega-3s and rich in fat (60% of consumed calories) showed amyloid-beta and tau protein concentrations respectively 8.7 and 1.5 times higher than the control group mice, whose food contained 7 times less fat. The high-fat diet also reduced drebrin protein levels in the brain, another characteristic of Alzheimer's disease.

"Metabolic changes induced by such a diet could affect the inflammatory response in the brain," suggests study co-author Carl Julien to explain the link between fat consumption and Alzheimer's.

In most Western countries, diets rich in saturated fats and poor in omega-3s are the norm. "Our findings lead us to believe that a diet containing more omega-3s and less saturated fat could prevent the development of Alzheimer's, at the very least among people genetically predisposed to the disease," comments Dr. Calon. "We cannot state with any certainty that what we have observed among transgenic mice also occurs in humans, but there is no harm in eating less fat and more omega-3s," concludes the researcher.


'/>"/>
Contact: Jean-Franois Hupp
jean-francois.huppe@dap.ulaval.ca
418-656-7785
Universit Laval
Source:Eurekalert

Page: 1 2

Related medicine news :

1. High-fat diet makes mice susceptible to liver injury
2. High-Fat Diet Can Disrupt Bodys Clock
3. Study provides hope that some transplant patients could live free of antirejection drugs
4. Study provides hope that some transplant patients could live free of anti-rejection drugs
5. HIV denialists spread misinformation online -- consequences could be deadly; and more
6. Virus Could Help Drive Obesity
7. Discovery of sugar sensor in intestine could benefit diabetes
8. Cranberry Could Juice Up Ovarian Cancer Treatment
9. Treating Diabetes During Pregnancy Could Lead to Thinner Kids
10. High-risk behaviors could lead to HIV epidemic in Afghanistan
11. Chinas 1-child policy could backfire on its elderly
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... NY (PRWEB) January 22, 2015 ... of Sports Medicine flagship journal Medicine & Science ... L-Citrulline before exercise may help reduce gastrointestinal (GI) ... 1 , Participants in the double-blind, placebo-controlled ...
(Date:1/22/2015)... Florida (PRWEB) January 22, 2015 IsoComforter, Inc. ... therapy machine with patented IsoTube design to treat specific body ... introduced the most progressive and easy to use patented cold ... post-operative and sports related orthopedic and muscle injuries. IsoComforter ...
(Date:1/22/2015)... Mass. (PRWEB) January 22, 2015 EBSCO ... (AMA) are expanding their relationship in an effort to ... around the world. While EBSCO has long made AMA journals ... a sales agent for The JAMA Network. , ...
(Date:1/22/2015)... Compare-autoinsurance.org has released a new blog post presenting a ... insurance policy . , Some types of vehicles cannot be ... newly released blog post to see if their vehicle qualifies for ... are some of the cars that cannot be covered by a ...
(Date:1/22/2015)... State Forestry Institute of Mecklenburg-Vorpommern in Germany ... from GEOSYSTEMS, a dedicated Hexagon Geospatial and Intergraph partner ... Geospatial’s ERDAS APOLLO for cataloging, managing, and ... clouds and documents. This effort will enable the State ...
Breaking Medicine News(10 mins):Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:EBSCO Expands Partnership with the American Medical Association 2Health News:EBSCO Expands Partnership with the American Medical Association 3Health News:EBSCO Expands Partnership with the American Medical Association 4Health News:Some Vehicles Cannot Be Covered By An Auto Insurance Policy! 2Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 2Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 3
... today announced an agreement with two non-profit organizations ... for rare blood cancers. The cooperative research ... shared commitment to move therapies for rare blood ... treatments can eventually be commercialized. The agreement is ...
... researchers have faced a baffling riddle: how to unravel a disorder ... brain. Now a UCLA study is the ... molecular level, resulting in an autistic brain that differs dramatically in ... online edition of Nature , the findings provide new insight ...
... News) -- A new drug that had shown promise in ... second stoke in someone who,s already had one, a new ... early because the drug, terutroban, showed no extra benefit. ... as effective as aspirin at preventing blood clots, and scientists ...
... Nationwide Children,s have received a grant from the National ... for MPS IIIB that has been shown effective in ... Mucopolysaccharidosis (MPS) IIIB, also known as Sanfilippo Syndrome B, ... the essential enzyme NAGLU. Children with MPS IIIB appear ...
... K. Babayan, MD, chief of the Department of Urology ... the Department of Urology at Boston University School of ... at their annual meeting in Washington, DC, last week ... specialty of urology and the AUA. Babayan received ...
... drink-drivers are more likely to be older, better-educated and ... study by academics at The University of Nottingham found ... triggers in alcohol-related offences committed by women. And ... to face the consequences of their crime can intensify ...
Cached Medicine News:Health News:NIH and non-profits sign research and development agreement 2Health News:Autism changes molecular structure of the brain, UCLA study finds 2Health News:Autism changes molecular structure of the brain, UCLA study finds 3Health News:Study Finds Aspirin Still Best at Preventing 2nd Stroke 2Health News:NIH grant for the move toward clinical trials targeting the lysosomal storage disease MPSIIIB 2Health News:Research study reveals profile for female drunk-drivers 2Health News:Research study reveals profile for female drunk-drivers 3
(Date:1/23/2015)... than a third of reproductive-aged women enrolled in Medicaid, and ... a prescription for an opioid pain medication each year during ... Mortality Weekly Report (MMWR). Opioids are typically ... pain.  They are also found in some prescription cough medications. ...
(Date:1/23/2015)... Jan. 23, 2015  HyGreen, Inc., a leader in hand ... with RCA Medical, a subsidiary of Ascendis Health Limited, ... Each year, hundreds of millions of patients around ... organisms are transmitted from patient to patient via the ...
(Date:1/23/2015)... 23, 2015 Cord Blood America, Inc. ( www.cordblood-america.com ) ... "Company")  filed a Preliminary Proxy Statement, Schedule 14A, with the ... provides an update for shareholders detailing why a "YES" vote ... Dear Shareholders, As we reflect upon the ...
Breaking Medicine Technology:Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3HyGreen Partners with RCA Medical in Johannesburg, South Africa 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 3Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 4
ICL manipulator, blunt, forked tip...
ICL manipulator with textured hemi-ball tip...
ICL manipulator with textured micro-ball tip....
0.25 mm diameter textured tip with protective guard....
Medicine Products: