Navigation Links
A good nose: RUB-Researchers decipher interaction of fragrances and olfactory receptors
Date:12/13/2011

n greater depth. They found that, in the dynamic interplay of the interaction between receptor and odorant molecule, specific chemical bonds, called hydrogen bridges, form and separate. "It's like a tango, where the female dancer constantly separates from her partner and joins him again at another point" explains Gerwert. "The receptor uses the dynamic hydrogen bonding pattern to distinguish between activating and non-activating odours."

Predictions for other olfactory receptors

The researchers established how many molecular junctions the interaction partners have to form in order for a smell to activate an olfactory receptor. They also managed to specifically manipulate a receptor protein in the model and in the experiment so that it detected papaya fragrance instead of apricot fragrance. "The findings can help to generate specific 'super-olfactory sensors' for a defined fragrance" says Hatt. "Since olfactory receptors not only occur in the nose, but also in many other tissues in the human body, for example in the prostate, in sperm, and in the intestines, the results may help to develop novel therapeutic approaches". The work was carried out as part of the Collaborative Research Centre SFB 642. The Mercator Foundation supported Prof. Gerwert with a grant.


'/>"/>

Contact: Dr. Klaus Gerwert
gerwert@bph.ruhr-uni-bochum.de
49-234-322-4461
Ruhr-University Bochum
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Chasing Perfection in the Nose: Revision Rhinoplasty
2. Georgetown Research Center Helps Reporters Decipher Health Reform Law & Impact on State Residents
3. Studies Decipher How Anti-Smoking Drugs Work
4. Deciphering hidden code reveals brain activity
5. Human working memory is based on dynamic interaction networks in the brain
6. Interaction Associates to Sponsor HCI Talent Management for Health Care Conference
7. Clear rules facilitate continued Web interaction among general practitioners
8. Concentration, timing and interactions are key when it comes to dietary compounds
9. Scientists unravel human-ecosystem interactions
10. U. Iowa biologists publish findings on cell interactions
11. UM researchers are studying child-mother interactions to design robots with social skills
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/25/2014)... The global HCIT outsourcing market is forecast ... $50.4 billion by 2018 from $35 billion in 2013. ... industry are driving the HCIT outsourcing market. These industries ... on core business, reduce operational and maintenance costs, increase ... hiring and training costs), share risk, and quickly implement ...
(Date:10/25/2014)... 2014 TASC (Total Administrative Services ... benefits account management services, announces the release of ... on taxes, reduce administrative workload, and lessen liability. ... and the efficient handling of complex, time-sensitive, and ... best meets their goals and objectives. The four ...
(Date:10/25/2014)... October 25, 2014 Homeowners that are ... ‘gone bad’ need wonder no more. Clean Crawls ... should watch out for when it comes to insulation ... to the article released by Clean Crawls, can cause ... that any insulation that has deteriorated, become damp, or ...
(Date:10/25/2014)... 24, 2014 (HealthDay News) -- Interrupting blood supply to an ... the risks associated with the surgery, according to a new ... the blood supply to the heart to be able to ... heart will reduce its ability to produce energy because it ... to another large muscle, such as an arm or a ...
(Date:10/25/2014)... 2014 (HealthDay News) -- A large influx of international ... to avoid tens of thousands of deaths from the ... predict. Using a specially designed mathematical model, ... outbreak in just one densely populated county of hard-hit ... of Monrovia. The researchers said that if international ...
Breaking Medicine News(10 mins):Health News:Global HCIT Outsourcing Market to Grow at 7.6% CAGR to 2018 Says a Premium Research Report Available at ReportsnReports.com 2Health News:Global HCIT Outsourcing Market to Grow at 7.6% CAGR to 2018 Says a Premium Research Report Available at ReportsnReports.com 3Health News:Global HCIT Outsourcing Market to Grow at 7.6% CAGR to 2018 Says a Premium Research Report Available at ReportsnReports.com 4Health News:TASC’s New Suites Offer Tax Savings and Protection 2Health News:5 Signs Indicating That Insulation Needs Replacing as Told By Clean Crawls in Recent Article 2Health News:Brief Interruption of Blood Supply to Limb Might Aid Heart Surgery: Study 2Health News:Experts Predict 'Catastrophic' Ebola Epidemic in West Africa if Aid Delayed 2
... 1 edition of The Journal of Immunology provide key ... Ph.D., a principal investigator in SBRIs Viral Vaccines Program ... Southwestern Medical Center, is senior author on one of ... critical symptom of AIDS, is likely a part of ...
... 6 Hundreds of health information,technology experts ... produced by Inland Northwest Health Services, September ... health information,technology projects and initiatives on the ... Services (INHS) manages one of the nation,s,most ...
... 6 Following today,s startling survey by,the Centers ... in youth,suicide in more than 15 years, the ... raft of expert tips and resources to help,youngsters, ... the warning,signs, life-saving tips, and free resources to ...
... should be the first line of prevention against ... hypertension. While banding is similarly effective in reducing ... fatal complications and is more expensive. These findings ... Transplantation, a journal by John Wiley & Sons. ...
... B. Ajluni, D.O., American Osteopathic,Association (AOA) President, CHICAGO, ... health insurance to 47 million --- as announced in ... a disturbing trend signaling,more must be done to increase ... return this week from the summer recess, reauthorizing the,State ...
... Sept. 6 The National,Osteoporosis Foundation (NOF) has ... a 10-city tour starting September 8th and culminating ... across the,country to Start Right, Stay Strong for ... and fun that offers individuals information on bone,health, ...
Cached Medicine News:Health News:SIV infection of natural hosts provides new insights into HIV disease complexity 2Health News:Jump in Youth Suicide Prompts National Children's Charity KidsPeace to Issue Tips on Prevention, Warning Signs 2Health News:Jump in Youth Suicide Prompts National Children's Charity KidsPeace to Issue Tips on Prevention, Warning Signs 3Health News:Jump in Youth Suicide Prompts National Children's Charity KidsPeace to Issue Tips on Prevention, Warning Signs 4Health News:Preventing variceal bleeding 2Health News:Preventing variceal bleeding 3Health News:National Osteoporosis Foundation Teams Up With Ladies Home Journal Magazine to Launch a 10-city Mall Walk Tour 2
(Date:10/25/2014)... Calif. , Oct. 24, 2014  America,s ... over friendly robotic competition at the  Medical Design ... on October 29-30 th at the ... will highlight local student built robots from the ... (FIRST) competition.  FIRST students and mentors will offer ...
(Date:10/25/2014)... 24, 2014  The National Association of Drug ... achieved by Kentucky,s real-time, ... The National Precursor Log Exchange (NPLEx) system automatically ... sale and helps flag meth offenders for law ... up NPLEx "watch lists" that notify them via ...
(Date:10/25/2014)... CUPERTINO, Calif. , Oct. 24, 2014 ... ) third quarter 2014 financial results press release, you ... will be broadcast live over the internet on Monday, ... pm Pacific Time). A live audio webcast ... homepage at http://www.durect.com and clicking "Investor Relations."  ...
Breaking Medicine Technology:Local robotics teams compete - a "FIRST" at next week's MD&M Minneapolis- October 29-30th at the Minneapolis Convention Center 2Local robotics teams compete - a "FIRST" at next week's MD&M Minneapolis- October 29-30th at the Minneapolis Convention Center 3Kentucky's NPLEx Technology Making Significant Progress 2DURECT Corporation Invites You to Join its Third Quarter 2014 Earnings Conference Call 2
... the risk of cardiovascular hospitalization or death by 24 ... Sanofi-aventis (Paris Bourse: EURONEXT: SAN; and ... that the ATHENA trial was published in the New ... (dronedarone), in addition to standard therapy, significantly reduced the ...
... a study published in The American Journal of ... Clinic psychiatrist Mark Frye, M.D., attempted to identify what ... to experience treatment-emergent mania (TEM).Bipolar disorder, also known as ... mood instability that can be serious and disabling. The ...
Cached Medicine Technology:New England Journal of Medicine Publishes Results From the Landmark ATHENA Trial with Multaq(R) (dronedarone) in Atrial Fibrillation 2New England Journal of Medicine Publishes Results From the Landmark ATHENA Trial with Multaq(R) (dronedarone) in Atrial Fibrillation 3New England Journal of Medicine Publishes Results From the Landmark ATHENA Trial with Multaq(R) (dronedarone) in Atrial Fibrillation 4New England Journal of Medicine Publishes Results From the Landmark ATHENA Trial with Multaq(R) (dronedarone) in Atrial Fibrillation 5New England Journal of Medicine Publishes Results From the Landmark ATHENA Trial with Multaq(R) (dronedarone) in Atrial Fibrillation 6Study Suggests New Treatment Approach May be Needed for Management of Depression in Some People With Bipolar Disorder 2Study Suggests New Treatment Approach May be Needed for Management of Depression in Some People With Bipolar Disorder 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: