Navigation Links
A gimmick-free weight-loss pill in the works
Date:1/26/2010

Montreal, January 26, 2010 A Universit de Montral research team is developing a pill composed of leptin, the protein that tells our brain to stop eating. "Mice deprived of leptin will not stop eating. They become so big they have trouble moving around," says Mose Bendayan, a pathology professor at the Universit de Montral Faculty of Medicine who has studied the leptin protein extensively.

Leptin regulates appetite in mammals and its levels decrease when fasting and rise during meals. It has been proven to be an appetite suppressant when administered intravenously to pathologically obese people.

Postdoctoral student Philippe Cammisotto is leading the charge for a leptin-based, appetite suppressing pill with Dr. Bendayan and mile Levy, a professor from the Department of Nutrition. "Taken orally, such a pill would provide obese people with the sensation of being full. They would eat less and in turn lose weight," says Dr. Cammisotto.

"We hope to start animal testing in 2010," says Bendayan. "The molecule is easy to synthesize and the protocol is ready."

After decades of building his reputation in fundamental research, Bendayan is happy to collaborate on something more tangible. "Obesity is a big problem in our society, no pun intended," says Bendayan. "To develop medication to combat obesity would be a great way for our laboratory to contribute to public health."

The new pill is being created based on a startling Universit de Montral discovery from 2006: leptin isn't only secreted by fatty tissues. "From the first bite of any meal, leptin levels skyrocket in the bloodstream. Yet this has nothing to do with the leptin stored in the fatty tissues," says Bendayan. "In the lab, we proved that up to 80 percent of cells in our stomach also produce leptin. Those are the ones that regulate appetite."

The Universit de Montral finding led to a different understanding of how the protein works, since leptin alone can't
'/>"/>

Contact: Sylvain-Jacques Desjardins
sylvain-jacques.desjardins@umontreal.ca
514-343-7593
University of Montreal
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Weight-Loss Surgeries Extend Lives
2. UMass Medical School study identifies the best weight-loss plans for heart health
3. FTC Attacks Infomercial Marketer to Silence Best-Selling Authors Weight-Loss Tips
4. Psychiatric Woes Can Postpone Weight-Loss Surgery
5. Studies Examine Life After Weight-Loss Surgery
6. NutriSystem Advances Weight-Loss Category
7. New Weight-Loss Drug Shows Promise in Early Study
8. USA TODAY Weight-Loss Challenge Returns For 5th Year With Eight Weeks of Compelling Stories and Online Features
9. Some Weight-Loss Drugs Might Disrupt Brain Growth in Kids
10. Weight-Loss Aids Bought on Internet Might Harm Your Heart
11. Weight-Loss Surgery Weighed as Diabetes Rx
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... Avid collector Andrew Hawley, from Vintage Rock ... Auditorium Seattle concert posters. The Doors were a smash hit ... year. The Seattle Eagles Auditorium concert was held on July ... to Eagles Auditorium in November the same year. The artist ... comes in three colors. The poster is a split fountain ...
(Date:9/23/2014)... News) -- Few children who take medication for ... the rates vary six-fold across counties in the ... alone can manage symptoms for many children with ... receive behavioral therapy (psychotherapy), the Rand Corp. researchers ... than 1,500 counties across the United States that ...
(Date:9/23/2014)... national report showing the benefits of preventing a ... Medicaid services was released today by the American ... Congress Must Save the Medicaid Primary Care Pay ... Access to Life-Saving Primary Care Will Expire," explains ... access to internists and pediatricians (and their related ...
(Date:9/23/2014)... Texas (PRWEB) September 23, 2014 ... for allergic rhinitis (AR) is highly fragmented, ... different SIT formulations available, under different regulatory ... between markets. Europe has the most developed ... (SLIT), and allergen immunotherapy tablets (AITs) all ...
(Date:9/23/2014)... York, New York (PRWEB) September 23, 2014 ... forward in courts around the country, Bernstein Liebhard LLP ... Court, Middle District of Florida on September 19th, the ... from a case filed in that jurisdiction on behalf ... growth) and other complications due to his use of ...
Breaking Medicine News(10 mins):Health News:Kids Taking ADHD Drugs Get Little Psychotherapy: Study 2Health News:Unless Congress acts, patients may soon lose access to primary care 2Health News:Unless Congress acts, patients may soon lose access to primary care 3Health News:Allergen extract Allergic Rhinitis Specific Immunotherapy Market to Grow $688.3m by 2018 Says a New Report Available at MarketOptimizer.org 2Health News:Allergen extract Allergic Rhinitis Specific Immunotherapy Market to Grow $688.3m by 2018 Says a New Report Available at MarketOptimizer.org 3Health News:Allergen extract Allergic Rhinitis Specific Immunotherapy Market to Grow $688.3m by 2018 Says a New Report Available at MarketOptimizer.org 4Health News:Risperdal Lawsuit News: Fraud, Negligence Per Se Claims Dismissed from Florida Complaint, Bernstein Liebhard LLP Reports 2Health News:Risperdal Lawsuit News: Fraud, Negligence Per Se Claims Dismissed from Florida Complaint, Bernstein Liebhard LLP Reports 3
... The makers of the WaveSense(TM) line of blood ... commitment to providing low cost, high accuracy, and high ... diabetes. The WaveSense Presto(TM) BGM can be found at ... strips (50 ct) are often as low as $22.88, ...
... The Hazelden Foundation, one of the world,s largest and ... centers, announced today that the Rev. Michael J. O,Connell ... of Trustees. O,Connell succeeds Norbert J. Conzemius, who served ... http://www.newscom.com/cgi-bin/prnh/20061128/CGTU038LOGO ) , , "The Rev. O,Connell ...
... -- GHX honored 12 healthcare provider and supplier ... chain performance. The awards were presented on Wednesday, June 3, ... Annual GHX Supply Chain Summit - the largest forum in ... of the healthcare supply chain. , , The theme ...
... in Under 4 years , , PLEASANTON, Calif., June ... Photopneumatic system in the United States. The installation of the ... base to approximately 1800 systems worldwide. The company has direct ... of distributors in over 20 countries in Asia, Europe and ...
... , , ... ANDS ) announced that it has entered into ... in gross proceeds in a "registered direct" offering through the ... estimates that net proceeds from the offering will be approximately ...
... 4 As the administration moves forward with health care ... research released this week by the Deloitte Center for Health ... Diego highlights how comparative effectiveness and consumerism will challenge the ... , During a time when the majority of U.S. consumers ...
Cached Medicine News:Health News:WaveSense Reduces Diabetes Testing Cost by 50% 2Health News:The Rev. Michael J. O'Connell Assumes Chairmanship of Hazelden Foundation Board of Trustees 2Health News:GHXcellence Awards Honor Healthcare Providers and Suppliers for Achievements in Supply Chain Performance 2Health News:GHXcellence Awards Honor Healthcare Providers and Suppliers for Achievements in Supply Chain Performance 3Health News:Aesthera Announces Installation of 1000th Photopneumatic System in US 2Health News:Anadys Pharmaceuticals, Inc. Announces Pricing of Common Stock and Warrant Offering 2Health News:Anadys Pharmaceuticals, Inc. Announces Pricing of Common Stock and Warrant Offering 3Health News:Health Plans Prepare for Health Care Reform: Comparative Effectiveness, Consumerism Drive Future Changes, According to Deloitte Study 2Health News:Health Plans Prepare for Health Care Reform: Comparative Effectiveness, Consumerism Drive Future Changes, According to Deloitte Study 3Health News:Health Plans Prepare for Health Care Reform: Comparative Effectiveness, Consumerism Drive Future Changes, According to Deloitte Study 4Health News:Health Plans Prepare for Health Care Reform: Comparative Effectiveness, Consumerism Drive Future Changes, According to Deloitte Study 5
(Date:9/23/2014)... Sept. 23, 2014 CASI Pharmaceuticals, Inc. (Nasdaq: ... the acquisition, development and commercialization of innovative therapeutics addressing ... market with a primary focus on China ... Shrotriya , MD, Chairman and Chief Executive Officer of ... appointment was made in connection with the recently announced ...
(Date:9/23/2014)...  Soligenix, Inc. (OTCQB: SNGX) (Soligenix or the ... address unmet medical needs in the areas of ... has appointed Rasappa Arumugham , PhD, as ... has over 25 years of diverse experience in ... of formulation research, analytical method development, quality control ...
(Date:9/23/2014)... Sept. 23, 2014  As physicians seek information ... communication channels to learn about new therapies or ... from a new report by global sales and ... that communicating via a customized mix of digital ... best opportunity to engage with physicians. And, productive ...
Breaking Medicine Technology:CASI Pharmaceuticals Announces Appointment Of Rajesh C. Shrotriya, MD To The Board Of Directors 2CASI Pharmaceuticals Announces Appointment Of Rajesh C. Shrotriya, MD To The Board Of Directors 3CASI Pharmaceuticals Announces Appointment Of Rajesh C. Shrotriya, MD To The Board Of Directors 4Soligenix Appoints Rasappa Arumugham, PhD, as Vice President of Biopharmaceutical Development 2Soligenix Appoints Rasappa Arumugham, PhD, as Vice President of Biopharmaceutical Development 3Soligenix Appoints Rasappa Arumugham, PhD, as Vice President of Biopharmaceutical Development 4As sales reps see doors close for in-person visits with physicians, digital doors open communication 2As sales reps see doors close for in-person visits with physicians, digital doors open communication 3As sales reps see doors close for in-person visits with physicians, digital doors open communication 4As sales reps see doors close for in-person visits with physicians, digital doors open communication 5
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: