Navigation Links
A giant interneuron for sparse coding
Date:5/13/2011

o the Kenyon cells manage to respond only extremely rarely, and with a sparseness that varies little over large ranges of stimulation conditions? Gilles Laurent of the Max Planck Institute for Brain Research and his group found that a single giant interneuron plays a key role. Along with colleagues in his lab (formerly at Caltech) and Great Britain, he has discovered that this neuron, with its extensive arbour, is activated by the entire Kenyon cell population and in turn inhibits them all back. "The giant interneuron and the Kenyon cells form a simple negative feed-back loop: the more strongly it is activated by the Kenyon cell population, the more strongly it curtails their activity in return", explains Laurent. The interneuron itself does not generate any action potentials, but inhibits Kenyon cells via nonspiking and graded release of the neurotransmitter GABA (gamma aminobutyric acid). This smooth, graded property enables this giant interneuron to do a kind of real-time, population averaging, thus carrying out an operation that might otherwise require the involvement of hundreds or thousands of individual spiking neurons.

The effectiveness of the giant interneuron is such that it can actually turn off the Kenyon cell population completely. But the research team also discovered that the giant interneuron is, in turn, controlled by another inhibitory neuron. "This allows the network activity to be potentiated or attenuated, and the sensitivity of this feedback loop to be adjusted", says Gilles Laurent. This is an important feature for brain regions such as the mushroom bodies, which are responsible not only for olfactory processing, but also for learning and memory. Mushroom bodies are where smells can be associated with other sensory modalities, enabling the formation of complex representations.

The scientists' findings show how massive negative feed-back loops can be formed in neuronal networks and what roles they can play. In vertebrates, the
'/>"/>

Contact: Prof. Gilles Laurent
laurentg@brain.mpg.de
49-050-682-02020
Max-Planck-Gesellschaft
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Earth from space: Giant iceberg enters Nares Strait
2. Giant Crayon Sweepstakes Giveaway Helps Businesses Increase Traffic for Back to School Promotions
3. “We've Got Balls” – Robin And The Giant Urge For Alternative Fuels
4. A Small Step For Today. A Giant Step For Tomorrow
5. Giant Eagle Pharmacy Free Antibiotics Program Surpasses $3 Million in Free Prescriptions
6. Cancer-associated long noncoding RNA regulates pre-mRNA splicing
7. Linc-ing a noncoding RNA to a central cellular pathway
8. The language of RNA decoded: Study reveals new function for pseudogenes and noncoding RNAs
9. New ICD-10 Training Tools Released with 3M Coding and Reimbursement System
10. Grantham University Announces New Certificate of Learning in Medical Coding and Billing
11. Is patient coding making hospitals appear better than they are?
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A giant interneuron for sparse coding
(Date:2/28/2015)... The Classic Denture Center , ... special. Throughout all of March patients can receive ... service can help overall mouth health and ... may notice certain symptoms that suggest the denture teeth ... include: , 1.    Pain, clicking, and popping in the joints, ...
(Date:2/28/2015)... 28, 2015 A study out of ... gene therapy procedure for the treatment of a hereditary ... Authored by Dr. Robert MacLaren, professor of ... the Lancet Medical Journal on January 16, 2014 , ... rare genetic disorder that mostly affects men and leads ...
(Date:2/28/2015)... 2015 Dr. Perry Patel , ... residents, recently announced a special offer for the Zoom!® ... option for new and established patients at his Pismo Beach ... bright, white smile, Dr. Patel and his staff are ... down from the regular price of $450. , Zoom! ...
(Date:2/28/2015)... NY (PRWEB) February 28, 2015 On Thursday, ... Kits Make It Easy For Scammers To Steal Your Data ... can get their hands on a DIY phishing kit, or ... it also touched on another important point about how everyone’s ... kits are often implemented, “like compromising legitimate content management systems ...
(Date:2/28/2015)... Powermod ” was featured on NewsWatch as part of its ... and coolest technology products and services available to consumers. Scott ... conducted the review and shared with viewers how they provide ... a low battery and no way to charge a phone ... daily basis. Even when a person does have a charger, ...
Breaking Medicine News(10 mins):Health News:Classic Denture Center in Portland Oregon is Offering March Discount 2Health News:New Gene Therapy Procedure Could Hold Key to Preventing Blindness for Certain Patients 2Health News:Pismo Beach Dentist Announces Special for Zoom! Teeth Whitening 2Health News:DIY Phishing and Malware Kits Make it Easy to Compromise Businesses in More Ways than One 2Health News:DIY Phishing and Malware Kits Make it Easy to Compromise Businesses in More Ways than One 3Health News:DIY Phishing and Malware Kits Make it Easy to Compromise Businesses in More Ways than One 4Health News:Solutions to Keep Phones Charged were Featured on NewsWatch Television on January 29, 2015 2
... vCJD is a rare, degenerative and fatal brain disorder. The ... or autopsy. Data from a recent study links // the ... transfusion. ,The first case of vCJD linked to ... that time, 17 people who had received blood donated from ...
... pulmonary disease, an often neglected disease of the respiratory system ... majority of people with the disease are smokers. Exposure to ... fires also comes into play in some cases. ,According ... it will be the third leading cause of death worldwide. ...
... cup of coffee at breakfast may be making an ... to determine how caffeine impacts blood sugar control and ... cups of instant coffee a day significantly impaired glucose ... studies have associated caffeine with decreased insulin sensitivity in ...
... attacks without chest pain are more often fatal. Chest pain ... chest pain //, some patients experience symptoms like fainting, shortness ... conducted a study to see how patients who have a ... recover. The study included information on 20,881 patients from 14 ...
... , that older men are not the only ones using ... (sildenafil) // users are men between ages 18 to 55. ... males, ages 18 and older, from 1998 to 2002. The ... group, with men older than 56 years receiving the majority ...
... children with hemophilia arthropathy, a severe form of hemophilia ... risk // than other children for developing osteoporosis ... hope in preventing osteoporosis from hitting these children, say ... impact activities than was previously advised by doctors. An ...
Cached Medicine News:
(Date:2/27/2015)... Feb. 27, 2015  Following a bipartisan vote ... moved H.R. 284, the Medicare DMEPOS Competitive Bidding ... for Homecare (AAHomecare) released a statement praising the ... pass the legislation. "Today,s mark-up of ... Ways and Means Committee is a critical step ...
(Date:2/27/2015)... 2015 Isis Pharmaceuticals, Inc. (Nasdaq: ... pro forma net operating loss (NOL) guidance and its ... position.  Isis, significantly improved financial results were due in ... payments the Company received from its partners.  Isis, pro ... nearly 60% improvement over its 2013 NOL of $40.2 ...
(Date:2/27/2015)...  Boston Scientific Corporation (NYSE: BSX ) ... Healthcare Conference on March 10 in Miami ... executive vice president and chief financial officer, and ... in a 25-minute question and answer session regarding the ... ET. Following a 5-minute break, a question and answer ...
Breaking Medicine Technology:Bidding Fix Takes Major Step Forward After Bipartisan Vote of House Ways and Means Committee 2Isis Reports Financial Results and Highlights for 2014 2Isis Reports Financial Results and Highlights for 2014 3Isis Reports Financial Results and Highlights for 2014 4Isis Reports Financial Results and Highlights for 2014 5Isis Reports Financial Results and Highlights for 2014 6Isis Reports Financial Results and Highlights for 2014 7Isis Reports Financial Results and Highlights for 2014 8Isis Reports Financial Results and Highlights for 2014 9Isis Reports Financial Results and Highlights for 2014 10Isis Reports Financial Results and Highlights for 2014 11Isis Reports Financial Results and Highlights for 2014 12Isis Reports Financial Results and Highlights for 2014 13Isis Reports Financial Results and Highlights for 2014 14Isis Reports Financial Results and Highlights for 2014 15Isis Reports Financial Results and Highlights for 2014 16Isis Reports Financial Results and Highlights for 2014 17Boston Scientific to Participate in the Barclays 2015 Annual Healthcare Conference 2
... TessArae® LLC, a global leader in resequencing microarray-based ... solutions for genetic testing of the mutations that ... TessArae,s expertise in microarray-based resequencing with novel nucleotide ... for all targeted mutations in multiple genes of ...
... 9 Women,s sexual health company, TivaMed, today announced it ... a 2010 launch of its Viveve system to OB/GYNs in ... believe captures the essence of our company focus on women,s ... "Viveve exists for the sole purpose of helping women restore ...
Cached Medicine Technology:TessArae Delivers Lower Cost Option to Genetic Testing Market 2Women's Sexual Health Company Changes Name in Preparation for Market Entry 2
Double ended with 0.5mm x 10mm and 1.0mm x 15mm blades; both blades gently curved; round serrated handle, In Titanium....
0.5mm "K" hook. Rounded knurled handle; shaft angled 11mm from tip; overall length 120mm, in Titanium....
Bend with "H" Shaped Tip, Right; Stainless Steel....
The GE e-Speed™scanner, the worlds fastest computed tomography (CT) imaging platform, delivers a new advanced tool for physicians to see and diagnose heart disease....
Medicine Products: