Navigation Links
A fresh look at existing therapies: Researchers explore ways to teach approved drugs new tricks
Date:10/24/2007

and is then rapidly internalized into the cell, in contrast to CD20, which is not taken inside cells as rapidly. The CD74 receptor is known to process antigens as part of the immune response, and recently was shown to be a survival factor in certain malignant cells, chronic lymphocytic leukemia, she said. So it appears to have a dual function, and the latter seems to make it an attractive candidate for antagonistic CD74 antibodies.

Veltuzumab is a second-generation humanized anti-CD20 antibody now in clinical testing, which works very similarly to rituximab, except that lower doses and shorter infusion times can be used, Stein says. Both of the drugs tested in this study, milatuzumab and veltuzumab, were developed by Immunomedics, Inc. Stein and her colleagues were funded through grants from the National Cancer Institute and the New Jersey Department of Health and Senior Services

These preclinical studies suggest benefit in testing the combination in patients, Stein says. We believe that combination antibody therapy, just as combination chemotherapy, will be the future for antibody-based immunotherapy, she said.


Neoadjuvant clinical trials for biomarker discovery: An old idea to solve a new problem: Abstract A229.

With the recent approval of four new agents and more coming through the drug development pipeline, treatment of advanced common kidney cancer has become a multiple choice decision of late − but one without a definitive answer. Physicians say they have no rational way to decide which drugs or drug combinations would work best for patients with renal cell carcinoma, especially those whose cancer has recurred and spread.

Now, researchers at the University of North Carolina at Chapel Hill are adapting the idea of neoadjuvant therapy − treating cancer before surgery − to renal cell carcinoma. Their intent is to use a short course of treatment to evaluate the performance of the new d
'/>"/>

Contact: Greg Lester
greg.lester@aacr.org
267-646-0554
American Association for Cancer Research
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8

Related medicine news :

1. Fresh approach to TB treatment
2. Fresh warnings to doctors regarding abortion pill
3. Refreshing Assam Tea Now At The Nearest Post Office
4. Fresh Cases of Bird-Flu Prepares the Ground for More Chicken Martyrs
5. Fresh Bird Flu Cases Spotted In Southern Russia
6. Pakistan Scared By Fresh Bird Flu Case
7. Fresh Polio Cases Reported In Uttar Pradesh
8. Nothing Can Equate Fresh Vegetables and Fruits
9. Fresh Outbreak Of Bird Flu In Nigeria
10. Foreign Fresher Students Offered Scholarship By Fudan
11. Fresh bird flu vaccines made in China
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... September 18, 2014 Alexandria, VA — ... today that 10 more communities have joined the growing ... health department accreditation. The decisions bring the number of ... 54. PHAB is the non-profit organization that administers the ... and protect the health of the public by advancing ...
(Date:9/18/2014)... 18, 2014 (HealthDay News) -- Rising temperatures in the ... spread to shallow waters that are becoming warmer, an ... reefs, ecologists report. A study of 40 species ... northward movement by the invasive and poisonous lionfish, according ... (NOAA) and the University of North Carolina-Wilmington, who published ...
(Date:9/18/2014)... "Medical staff need better ways to ... the patient's privacy," said one of two inventors from ... order to supply caregivers with the equipment they need ... prototype for The Helper to make it easier to ... patient onto his or her side. It also securely ...
(Date:9/18/2014)... One of the most capable and sophisticated ... ShandsCair Flight Program’s new EC155 B1, will be ... the Air Medical Transport Conference (AMTC), Sept. 22-24, in ... service ShandsCair EC155 and the Vanderbilt University LifeFlight ... highlight Airbus Helicopters broad, industry leading line-up of ...
(Date:9/18/2014)... HealthDay Reporter , THURSDAY, Sept. 18, 2014 (HealthDay ... patients seeking care at larger urban hospitals are likely to ... at smaller or more rural facilities, new research suggests. ... emergency care varies dramatically across hospitals in the United States," ... Renee Hsia, an associate professor at the University of California, ...
Breaking Medicine News(10 mins):Health News:Ten More Communities Reaping Benefits of National Accreditation 2Health News:Ten More Communities Reaping Benefits of National Accreditation 3Health News:Ten More Communities Reaping Benefits of National Accreditation 4Health News:Rising Atlantic Ocean Temperatures Could Pose Threat to Reefs 2Health News:Airbus Helicopters Inc. Features Industry-leading Models at AMTC 2Health News:Airbus Helicopters Inc. Features Industry-leading Models at AMTC 3Health News:Airbus Helicopters Inc. Features Industry-leading Models at AMTC 4Health News:ER Waiting Times Vary Significantly, Studies Find 2Health News:ER Waiting Times Vary Significantly, Studies Find 3
... ... a clinical trial that is testing whether specialized contact lenses can slow or halt ... and Robert Davis, working with EyeVis Eye and Vision Research Institute, recently reported on ... , ...
... Family Research Council President Tony Perkins responded to ... Obama,s executive order for federal funding of human embryonic ... the NIH guidelines remove life-protecting limits on federal funding ... , (Logo: http://www.newscom.com/cgi-bin/prnh/20080930/FRCLOGO ) ...
... ... a national leader in accounts receivable management, and collection services to the healthcare industry has ... in Vero Beach, Florida. , ... Vero Beach, FL (PRWEB) July 7, 2009 -- National healthcare receivables industry leader, Medical ...
... a Woman,s Right to Choose , , ARLINGTON ... breast reconstruction procedures performed in 2008, nearly 70 percent ... not informed of the reconstructive options available to them, ... by the American Society of Plastic Surgeons (ASPS) shows ...
... July 7 The Anthropedia Foundation, a non-profit organization ... Know Yourself , an innovative DVD series designed ... and healthier lives. The series is a step-by-step guide ... part focuses on straightforward concepts and simple exercises that ...
... sellers appears to reduce the trafficking of guns to ... the Johns Hopkins Bloomberg School of Public Health. Preventing ... 85 percent of guns recovered by police were recovered ... of the guns according to prior research from the ...
Cached Medicine News:Health News:Can a Contact Lens Cure Nearsightedness? Five-Year Clinical Study Testing Corneal Reshaping Therapy as Possible Method to Arrest Myopia 2Health News:Can a Contact Lens Cure Nearsightedness? Five-Year Clinical Study Testing Corneal Reshaping Therapy as Possible Method to Arrest Myopia 3Health News:NIH Stem Cell Guidelines Ethically Irresponsible, Scientifically Unworthy, Useless to Patients, Says Family Research Council 2Health News:Medical Data Systems, Inc. (MDS) Announces Operations Expansion and Opening of its Primary Collections Operations Office 2Health News:Medical Data Systems, Inc. (MDS) Announces Operations Expansion and Opening of its Primary Collections Operations Office 3Health News:Are Breast Cancer Patients Being Kept In The Dark? 2Health News:Knowing Yourself Can Improve Your Health and Happiness 2Health News:Knowing Yourself Can Improve Your Health and Happiness 3Health News:Regulation and oversight of gun sales reduces trafficking to criminals 2Health News:Regulation and oversight of gun sales reduces trafficking to criminals 3
(Date:9/18/2014)... , Sept. 18, 2014  Casen Buswell has a rare ... to harden.  His case is one of only 14 known ... The only hospital in the United States ... offering treatment with the dual wave-length laser, is Methodist Children,s ... Antonio . Using a laser available in ...
(Date:9/18/2014)... Sept. 18, 2014 This BCC Research report discusses the ... players, market growth and size, and opportunities for different devices ... through 2018. Patent analysis in the report focuses on technological ... Europe and Japan ... and discuss the global medical device technologies market. - Analyze ...
(Date:9/18/2014)... and LONDON , ... era for biopharmaceutical companies. Competition for innovation, increasing ... to keep up with the fast-changing environment are ... influence clinical trials, and clinical trial costs continue ... patient recruitment. Studies conducted by industry ...
Breaking Medicine Technology:Methodist Children's Hospital In San Antonio, TX Only Hospital In The U.S. Treating Rare Vascular Condition With Dual Wave-Length Laser 2Medical Devices: Technologies and Global Markets 2Medical Devices: Technologies and Global Markets 3Medical Devices: Technologies and Global Markets 4Patient Recruitment in Asia Biotech and Pharma Companies 2Patient Recruitment in Asia Biotech and Pharma Companies 3
... Va., and BOSTON, Oct. 28 The final results of ... meeting of the American Association for the Study of Liver ... a combination therapy of peginterferon alfa-2a and ribavirin. It intended ... sustained viral response in genotype 1 patients with HCV who ...
... 28 Featuring the lowest dose and the fastest ... Flash dual-source computed tomography (CT) scanner is now poised ... to better serve its pediatric patients. The SOMATOM Definition ... that systems previously required to scan even the tiniest ...
Cached Medicine Technology:Difficult-to-Treat Patient Populations Respond Positively to Hepatitis C Treatment 2Siemens Delivers Flash Speed, Lowest Dose to Arnold Palmer Hospital for Children 2Siemens Delivers Flash Speed, Lowest Dose to Arnold Palmer Hospital for Children 3
... autoimmune testing feature single-well ANA screen and ... reflex tests including dsDNA, and 6 individual ... (La), Scl-70 and Jo-1. In addition, our ... of products for Cardiolipins (IgA, IgG, IgM), ...
... ELISA products for autoimmune testing feature single-well ... well as specific reflex tests including dsDNA, ... SS-A (Ro), SS-B (La), Scl-70 and Jo-1. ... a full line of products for Cardiolipins ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: