Navigation Links
A decade of refinements in transplantation improves long-term survival of blood cancers
Date:11/24/2010

er and sicker than those who were treated in the mid-1990s.

McDonald said he and his colleagues can only speculate about the reasons for the improved outcomes because the study was retrospective and was not a randomized comparison of transplant techniques and treatments among groups of patients. However, the authors deemed several changes in clinical practices to be important in risk reduction, many of which were the result of ongoing clinical research (including various randomized clinical trials) conducted at the Hutchinson Center and at other major transplant centers around the world:

  • Careful pharmacologic monitoring and dose adjustments to avoid under and over treatment with the potent chemotherapeutic agents used in transplantation.
  • Use of reduced-intensity conditioning in older and less healthy patients.
  • Less use of high-dose systemic immune suppression to treat acute GVHD.
  • Use of the drug ursodiol to prevent liver complications.
  • New methods for early detection of viral and fungal infections as well as preventive therapy for such infections.
  • The use of better and less toxic anti-fungal drugs to treat serious infections caused by Candidal organisms and molds.
  • Use of donor peripheral blood hematopoietic cells instead of bone marrow as the source of donor cells, which results in faster engraftment and return of immunity.
  • More accurate matching of marrow or stem cell donors with unrelated patients.

"This research and the improved outcomes are the result of a team approach to one of the most complex procedures in medicine," McDonald said. Medical oncologists and transplantation biologists at the Hutchinson Center are supported in the care of patients by specialists in infectious diseases, pulmonary and critical care medicine, nephrology, gastroenterology and hepatology, and by highly skilled nurses and support staff.

"Each of these programs is involved in ongoing clinical research into the com
'/>"/>

Contact: Christi Loso
closo@fhcrc.org
206-667-5215
Fred Hutchinson Cancer Research Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Health Groups Ask Supreme Court to Authorize Financial Penalties on Tobacco Companies for Decades of Wrongdoing
2. Scientific community to set research agenda for infection prevention and control for next decade
3. Next decade offers promise for treatment of spinal cord injuries
4. What Causes A Person To Be Mentally Ill? Author Who Has Spent Decades Researching Topic Says He Has the Answer
5. ASPS Reports Cosmetic Plastic Surgery Procedures Down in 2009 -- Up 69% in First Decade of New Millennium
6. MUHC/McGill Ocular Pathology Laboratory celebrates a decade of progress
7. Medical costs of cancer have nearly doubled over the past 2 decades
8. U.S. Cancer Costs Double in Two Decades
9. Summertime Decadence: Rodelle Cocoa Launches in Western Canada
10. Sleep Disorder May Help Predict Parkinsons Decades Earlier
11. Decade-long trial confirms benefts of steroid withdrawal for transplant patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2015)... NY (PRWEB) May 04, 2015 Ticket Down ... 2015 International Champions Cup (ICC) . While the World ... and is held every four years, the International Champions Cup ... the tournament saw the all-time attendance record for soccer in ... from the Big House at the University of Michigan. This ...
(Date:5/4/2015)... and Seattle, WA (PRWEB) May 04, 2015 ... formation of a collaboration to facilitate development of NM108, ... ophthalmic disorders that lead to blindness, including Diabetic Retinopathy. ... MiDROPS™ formulation platform developed by EyeCRO, which can deliver ... via a topical eyedrop. , Under the terms ...
(Date:5/4/2015)... 04, 2015 Ticket Down is a reputable ... Paul Jones Arena in Charlottesville, VA. McCartney is ... the music business and this beloved performer continues to roll ... former member of two legendary groups: Wings and The Beatles, ... business since 2013 on the “Out There” tour and has ...
(Date:5/4/2015)... 04, 2015 New findings released today ... Association (ABTA) show that people diagnosed with a brain ... options, including clinical trials, at the time of diagnosis, ... difficult decisions about their course of treatment. The release ... first nationwide brain tumor volunteer network, the ABTA CommYOUnity™, ...
(Date:5/4/2015)... (PRWEB) May 04, 2015 Pricing Healthcare ... to $3,000) of one patient receiving care at St. ... The procedure must be performed by July 15th, 2015, ... pay in full up front and forego the filing of ... more economically burdensome every year, and it devastates more and ...
Breaking Medicine News(10 mins):Health News:Cheap 2015 International Champions Cup (ICC) Tickets: Ticket Down Slashes Ticket Prices on International Champions Cup (ICC) Presale Tickets 2Health News:Cheap 2015 International Champions Cup (ICC) Tickets: Ticket Down Slashes Ticket Prices on International Champions Cup (ICC) Presale Tickets 3Health News:Cheap 2015 International Champions Cup (ICC) Tickets: Ticket Down Slashes Ticket Prices on International Champions Cup (ICC) Presale Tickets 4Health News:EyeCRO and NeuMedics Announce Collaboration to Utilize MiDROPS™ Technology for the Development of NM108 2Health News:EyeCRO and NeuMedics Announce Collaboration to Utilize MiDROPS™ Technology for the Development of NM108 3Health News:Paul McCartney Tickets at John Paul Jones Arena in Charlottesville, VA: Ticket Down Slashes Paul McCartney Ticket Prices in Charlottesville at the John Paul Jones Arena 2Health News:American Brain Tumor Association Poll Underscores Need for Greater Awareness and Education at Time of Diagnosis 2Health News:American Brain Tumor Association Poll Underscores Need for Greater Awareness and Education at Time of Diagnosis 3Health News:Pricing Healthcare to Pay a Patient's Bill for a Procedure at Utah Facility 2Health News:Pricing Healthcare to Pay a Patient's Bill for a Procedure at Utah Facility 3
... (BRONX, NY) Recurrent and metastatic endometrial and ... have spread to other organs and typically have developed ... chemotherapy may not be able to endure more chemo. ... Yeshiva University have shown that a combination of two ...
... Four associations representing the state,s 114 hospitals have ... budget for 2010.Among other principles, the groups urged the ... funds and agreed on a minimum floor that all ... agreement was shared today with members of the state ...
... Immtech Pharmaceuticals, Inc. (NYSE Amex: IMM ) ... operations. This restructuring will direct resources to business opportunities ... of proprietary compounds. With this change, the Company ... for Pharmaceutical Development & Chief Medical Officer is being ...
... acid, also in nuts, limits wrinkling , , TUESDAY, April ... are nutritious. But new research shows that a compound found ... and repair skin damage caused by the sun. , Researchers ... strawberries, cranberries and pomegranates, to human skin cells in the ...
... get worse as you get older may actually be a ... that senior citizens who think older people should perform poorly ... who do not buy in to negative stereotypes about aging ... month, psychology professor Dr. Tom Hess and a team of ...
... April 21 NBTY, Inc. (NYSE: NTY ) ( ... nutritional supplements, today announced it will web cast a conference call ... ( www.NBTY.com ), on Friday, April 24, 2009 at ... fiscal second quarter will be issued at 4:30 PM (ET) on ...
Cached Medicine News:Health News:New treatment shows promise against recurrent gynecologic cancers 2Health News:Hospital Groups Stand United on State Budget 2Health News:Hospital Groups Stand United on State Budget 3Health News:Hospital Groups Stand United on State Budget 4Health News:Immtech to Reorganize Research and Development Operations 2Health News:Immtech to Reorganize Research and Development Operations 3Health News:Compound in Berries May Lessen Sun Damage 2Health News:Think memory worsens with age? Then yours probably will 2Health News:NBTY to Web Cast Fiscal Second Quarter Conference Call 2Health News:NBTY to Web Cast Fiscal Second Quarter Conference Call 3
(Date:5/4/2015)... May 4, 2015 Southfield Capital, ... firm, announced today that it completed a ... Communications. BioPharm specializes in the development and multi-channel ... pharmaceutical and biotechnology industries. Through ... shareholders half of their invested capital and ...
(Date:5/4/2015)... BOSTON , May 4, 2015 PAREXEL International ... be presenting at the UBS Healthcare Conference on Monday, May ... Senior Vice President and Chief Financial Officer will be making ... a.m. ET. A live webcast of the presentation ... at www.PAREXEL.com in the Upcoming Events portion of ...
(Date:5/4/2015)... 2015  Impax Laboratories, Inc. (NASDAQ: IPXL ) ... roles, appointing  Donna M. Hughes, as Senior Vice President, ... Senior Vice President, Chief Compliance Officer. Both Ms. Hughes ... Chief Executive Officer, Fred Wilkinson . ... the Impax team," said Fred Wilkinson , President ...
Breaking Medicine Technology:Southfield Capital and BioPharm Communications Announce Dividend Recapitalization 2PAREXEL International to Present at UBS Healthcare Conference 2Impax Strengthens Leadership Team by Adding New Senior Vice Presidents for Human Resources and Compliance 2Impax Strengthens Leadership Team by Adding New Senior Vice Presidents for Human Resources and Compliance 3
... , , SAN FRANCISCO, Aug. 21 ... first annual "Bridge to Hope," an all-day music festival set to be held ... from 11:00 a.m. to 7:00 p.m. The event will also include an ... selection of gourmet fare from a number of the city,s favorite eateries. , ...
... , , , ... Bay(R) Pharmaceuticals , Inc. (NYSE-Amex: NBY ), a ... prevention of a wide range of bacterial, viral, and fungal infections, ... on Antimicrobial Agents and Chemotherapy (ICAAC) in San Francisco, CA. ...
Cached Medicine Technology:Tickets On Sale Now: 'Bridge to Hope' All-Day Music Festival to Feature Top Artists, Gourmet Food, Art Show, Saturday, September 26th at Fort Mason's Great Meadow 2Tickets On Sale Now: 'Bridge to Hope' All-Day Music Festival to Feature Top Artists, Gourmet Food, Art Show, Saturday, September 26th at Fort Mason's Great Meadow 3Tickets On Sale Now: 'Bridge to Hope' All-Day Music Festival to Feature Top Artists, Gourmet Food, Art Show, Saturday, September 26th at Fort Mason's Great Meadow 4Tickets On Sale Now: 'Bridge to Hope' All-Day Music Festival to Feature Top Artists, Gourmet Food, Art Show, Saturday, September 26th at Fort Mason's Great Meadow 5NovaBay Pharmaceuticals to Present New Data on Lead Anti-Infective Compound at the 2009 ICAAC Annual Meeting 2NovaBay Pharmaceuticals to Present New Data on Lead Anti-Infective Compound at the 2009 ICAAC Annual Meeting 3
... procedures where stability, access, and precise, ... cantilevered low attenuation carbon fiber tabletop ... radiolucent area is free of cross ... unobstructed C-Arm positioning. Functional design provides ...
...
... Immunoassay Control is a ... designed to complement the ... Immunoassay Plus Controls. This ... to include more complex ...
Liquichek Cardiac Markers Plus Control is a premium, comprehensive cardiac assessment control with many analytes and long stability....
Medicine Products: