Navigation Links
A decade of refinements in transplantation improves long-term survival of blood cancers
Date:11/24/2010

SEATTLE A decade of refinements in marrow and stem cell transplantation to treat blood cancers significantly reduced the risk of treatment-related complications and death, according to an institutional self-analysis of transplant-patient outcomes conducted at Fred Hutchinson Cancer Research Center.

Among the major findings of the study, which compared transplant-patient outcomes in the mid-'90s with those a decade later: After adjusting for factors known to be associated with outcome, the researchers observed a statistically significant 60 percent reduction in the risk of death within 200 days of transplant and a 41 percent reduction in the risk of overall mortality at any time after transplant.

"Everything we looked at improved a decade after the initial analysis," said George McDonald, M.D., a Hutchinson Center gastroenterologist and corresponding author of the paper, which was published (date) in the New England Journal of Medicine.

McDonald and colleagues reviewed the outcomes of 1,418 transplant patients who received peripheral-blood stem cells or bone marrow from unrelated donors between 1993 and 1997 and compared them to 1,148 patients who had the same procedures between 2003 and 2007. The malignancies treated included forms of leukemia, lymphoma, multiple myeloma and myelodysplastic syndrome.

The researchers also found that the estimated one-year overall survival rates for both groups were 55 percent and 70 percent, respectively. They also observed statistically significant declines in the risks of severe graft-vs-host-disease; infections caused by viruses, bacteria and fungi; and complications caused by damage to the lungs, kidney and liver.

Lead author and biostatistician Ted Gooley, Ph.D., noted that the analysis presents the findings in terms of the changes in the "risk" or "hazard" of death and transplant complications after taking into account the fact that the patients treated in the mid-2000s were, on average, old
'/>"/>

Contact: Christi Loso
closo@fhcrc.org
206-667-5215
Fred Hutchinson Cancer Research Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Health Groups Ask Supreme Court to Authorize Financial Penalties on Tobacco Companies for Decades of Wrongdoing
2. Scientific community to set research agenda for infection prevention and control for next decade
3. Next decade offers promise for treatment of spinal cord injuries
4. What Causes A Person To Be Mentally Ill? Author Who Has Spent Decades Researching Topic Says He Has the Answer
5. ASPS Reports Cosmetic Plastic Surgery Procedures Down in 2009 -- Up 69% in First Decade of New Millennium
6. MUHC/McGill Ocular Pathology Laboratory celebrates a decade of progress
7. Medical costs of cancer have nearly doubled over the past 2 decades
8. U.S. Cancer Costs Double in Two Decades
9. Summertime Decadence: Rodelle Cocoa Launches in Western Canada
10. Sleep Disorder May Help Predict Parkinsons Decades Earlier
11. Decade-long trial confirms benefts of steroid withdrawal for transplant patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2015)... ... , ... Specialty Technical Publishers (STP) and Specialty Technical Consultants ... EHS audit protocol for the European Union. Leading companies around the world use ... and rapidly collect, share, archive, and export audit findings in a cost-effective manner. ...
(Date:8/31/2015)... ... September 01, 2015 , ... Spinal fusion surgery – ... required a long, arduous recovery. However, today’s minimally invasive fusions achieve similar results ... and minimal muscle damage. These advantages of minimally invasive surgery redeem the procedure’s ...
(Date:8/31/2015)... ... 2015 , ... Dental clinicians from Newcastle University, United Kingdom, ... learn more about its integrated approach to diabetes care. , Philip Preshaw, BDS, ... Medicine at Newcastle University, and Susan Bissett, National Institute for Health Research Clinical ...
(Date:8/31/2015)... ... 31, 2015 , ... Wound Care Advantage, a leader in ... to Hyperbaric Medicine Course. The next UHMS approved 40-hour Introduction to Hyperbaric Medicine ... Long Beach, CA. The meeting is open for registration from physicians, clinicians and ...
(Date:8/31/2015)... Dayton, Ohio (PRWEB) , ... August 31, 2015 ... ... Jenny Michael as Vice President, Marketing and Corporate Communications. In this capacity, Michael ... , CareSource is an industry leader in consumer-focused programs that have contributed ...
Breaking Medicine News(10 mins):Health News:Specialty Technical Publishers (STP) and Specialty Technical Consultants(STC) Publish Environmental, Health & Safety (EHS) Audit Protocol for the European Union 2Health News:Specialty Technical Publishers (STP) and Specialty Technical Consultants(STC) Publish Environmental, Health & Safety (EHS) Audit Protocol for the European Union 3Health News:Specialty Technical Publishers (STP) and Specialty Technical Consultants(STC) Publish Environmental, Health & Safety (EHS) Audit Protocol for the European Union 4Health News:Minimally Invasive Spinal Fusions Squash Back Pain without Arduous Recovery 2Health News:Minimally Invasive Spinal Fusions Squash Back Pain without Arduous Recovery 3Health News:Minimally Invasive Spinal Fusions Squash Back Pain without Arduous Recovery 4Health News:Western Diabetes Institute Collaborates with UK team 2Health News:Western Diabetes Institute Collaborates with UK team 3Health News:Western Diabetes Institute Collaborates with UK team 4Health News:Registration Opens for Wound Care Advantage’s Second UHMS Approved 40-Hour Introduction to Hyperbaric Medicine Course 2Health News:Registration Opens for Wound Care Advantage’s Second UHMS Approved 40-Hour Introduction to Hyperbaric Medicine Course 3Health News:Registration Opens for Wound Care Advantage’s Second UHMS Approved 40-Hour Introduction to Hyperbaric Medicine Course 4Health News:CareSource Names Vice President, Marketing and Corporate Communications 2
... imaging is significantly superior to 16 slice multidetector ... repair of abdominal aortic aneurisms (EVAR), according to ... San Giovanni in Bellinzona, Switzerland. , Endovascular ... viable alternative treatment to open surgery for many ...
... is now,open for CleanMed 2008, the healthcare ... green building. The event is,produced by leading ... partners Consorta, the Heinz Endowments, Kaiser Permanente ... CleanMed attracts major health care systems, product ...
... N.Y., April 11 Polymedco, Inc. is,pleased to ... PATHFAST rapid point of care system utilizes a ... that allows,this system to report highly accurate results ... employs individual,cartridge-based technology utilizing a whole blood sample., ...
... in differentiating the blood supply to medial and lateral breast ... to a study conducted by researchers at the University of ... Petah Tikva, Israel. , Blood supply of medial tumors ... may be supplied by both the internal or lateral mammary ...
... with 3T MR-guided focused ultrasound (MRgFUS) is safe, ... conducted by researchers at Weill Cornell Medical College ... women in the United States have clinically symptomatic ... with hysterectomy or myomectomy. However, in the past ...
... blood cell production is controlled could lead to improvements ... to West Australian medical researchers. , The findings are ... of the American Society of Hematology and the worlds ... led by Western Australian Institute for Medical Research (WAIMR) ...
Cached Medicine News:Health News:MRI better than MDCT in detecting endoleaks, study says 2Health News:Creating Healing Environments: Healthcare Industry's Largest Sustainability Conference to be Held May 20-22 in Pittsburgh 2Health News:Twin findings raise hopes of improved anemia treatments 2
(Date:9/1/2015)... MOUNTAIN VIEW, Calif. , Sept. 1, ... of the cardiovascular image management market, Frost ... with the 2015 European Frost & Sullivan ... Netherlands -based PMI has designed innovative ... product lines—which deliver precise and reproducible quantitative ...
(Date:9/1/2015)... 1, 2015  Abbott (NYSE: ABT ) announced today ... randomized trial comparing the safety and effectiveness of Abbott,s ... , Abbott,s market-leading, permanent drug eluting stent. The trial ... and enrolled 400 people with coronary artery ... results will be featured at a late-breaking session today ...
(Date:9/1/2015)... September 1, 2015 BerGenBio AS ... announces that it has appointed Hilde Furberg ... to its Board of Directors, effective immediately. ... experience in pharma and biotech and is currently Senior ... company. Previously her role was Vice President and General ...
Breaking Medicine Technology:Frost & Sullivan Applauds Pie Medical Imaging for Highly Innovative Quantitative Software for Cardiovascular Diagnosis 2Frost & Sullivan Applauds Pie Medical Imaging for Highly Innovative Quantitative Software for Cardiovascular Diagnosis 3Frost & Sullivan Applauds Pie Medical Imaging for Highly Innovative Quantitative Software for Cardiovascular Diagnosis 4Frost & Sullivan Applauds Pie Medical Imaging for Highly Innovative Quantitative Software for Cardiovascular Diagnosis 5Abbott Announces Positive Results of Its Naturally Dissolving Stent from ABSORB Japan Study 2Abbott Announces Positive Results of Its Naturally Dissolving Stent from ABSORB Japan Study 3Abbott Announces Positive Results of Its Naturally Dissolving Stent from ABSORB Japan Study 4BerGenBio Appoints Non-Executive Directors 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: