Navigation Links
A crystal ball for brain cancer?
Date:8/16/2009

is colleagues focused on glioblastoma, the most common and deadly form of adult brain tumor, striking 12,000 Americans a year. Despite therapy with surgery, radiation and chemotherapy, the average glioblastoma patient lives only 12 to 15 months after diagnosis.

Survival rates drop even lower if the tumor returns. Conventional therapies produce little benefit; only 8 to 15 percent of patients survive without tumor growth six months after treatment.

The UCLA team studied 82 patients who had undergone surgery and radiation therapy to remove glioblastoma. Half of the patients received infusions of Avastin every two weeks. All underwent monthly brain scans by magnetic resonance imaging (MRI) to monitor change.

The researchers analyzed the MRI scans of the patients whose tumors returned. Explaining what the team saw requires an understanding of how the tumor creates an independent blood supply.

Cancer cells secrete a growth factor called VEGF that spurs the growth of new blood vessels to supply the tumor with oxygen and nutrients. Avastin blocks VEGF, essentially starving the tumor to death.

This process launches a chain of events that is detectable by MRI. Oxygen-starved cells produce more VEGF, which causes blood vessels to leak fluids into the tumor and surrounding tissue. This results in swelling, which boosts water's ability to move freely in the tumor and brain tissue. As cells disintegrate, they no longer pose a physical barrier to water movement.

"We theorized that tumors with more water motion would also have higher VEGF levels," explained Pope. "Because Avastin targets VEGF, it made sense that the drug would work better in tumors with high levels of the growth factor."

By measuring the amount of water motion within the tumor, the researchers were able to predict with 70 percent accuracy which patients' tumors would progress within six months and which would not. They detected grea
'/>"/>

Contact: Elaine Schmidt
eschmidt@mednet.ucla.edu
310-794-2272
University of California - Los Angeles
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Elton John, Billy Crystal, Tony Bennett, and Gladys Knight Help Starkey Hearing Foundation Raise More than $5 Million at Annual Fundraiser
2. Bausch & Lomb Receives Approval of Crystalens HD in Quarter Diopter Steps
3. Crystal Heart Award Presented to Telemundo for Coverage of Organ Donation
4. ASGE and ASGE Foundation hold Crystal Awards Dinner as part of Digestive Disease Week
5. Frost & Sullivan Recognizes Zecotek Photonics Medical Imaging Achievement, Development of Next-Generation Scintillation Crystals and Photo Detector Technology
6. MSU researcher links cholesterol crystals to cardiovascular attacks
7. Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on Authentidate Holding Corp.
8. The New Crystalens HD Gives Many Baby Boomers and Seniors an Opportunity to See Clearly at All Distances while Reducing or Eliminating the Need for Glasses
9. Bausch & Lombs Crystalens to be Featured in Florida Advertising Campaign.
10. UCLA scientists develop crystal ball for personalized cancer treatment
11. Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on BELLUS Health Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A crystal ball for brain cancer?
(Date:1/22/2015)... TN (PRWEB) January 22, 2015 Gabe’s Chemo Duck ... Duck App, the first app ever created for kids with cancer. ... Apple phones and devices, is filled with enjoyable games to help ... and treatments. The free app helps to keep kids entertained, educated ...
(Date:1/22/2015)... January 23, 2015 VogueQueen is a seasoned ... prices and many designers are thrilled to have it lead ... announces its new collection of prom dresses for the global ... drive the strategic vision and he focuses on continuing the ...
(Date:1/22/2015)... a famous wedding dress company offering many trendy designs. Today, ... Twitter, and Pinterest. The fans will have an opportunity to ... week. , Moreover, the company has extended its 2015 New ... for more information. , Angelweddingdress is a famous ...
(Date:1/22/2015)... AngelWeddingDress, the premier women’s dress supplier, ... dresses. View website of AngelWeddingDress.com to find ... wedding dresses online for a bridal party. AngelWeddingDress offers ... for them. Its maternity wedding dresses are specially designed ...
(Date:1/22/2015)... Florida (PRWEB) January 22, 2015 Juvent ... today at the 2015 PGA Merchandise Show to bestow ... and incredible female amateur golfer, Arlene McKitrick. The award ... female amateur golf tournament win. She won her first ...
Breaking Medicine News(10 mins):Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3
... , Feb. 11 Grant Medical Center recently completed ... give hope to millions of patients facing lower limb amputations from ... the legs that affects 10 million Americans. If left untreated, it ... , The December issue of The Journal of Vascular Surgery ...
... see any blockage in arteries, study finds , THURSDAY, Feb. ... doctors whether it,s safe to discharge a patient who has ... study shows. , The coronary artery calcium scoring (CACS) test ... quickly provide doctors with a detailed image of the heart ...
... NEW YORK , Feb. 11 Oral health ... the link between poor oral health and such conditions as stroke, ... may show preliminary signs in your mouth, before other areas of ... habits can affect your oral health.  Therefore, it,s wise to pay ...
... ... in Columbia, S.C., says developments in lawsuits pending against a Pfizer anti-smoking drug don’t ... ... 2010 -- The anti-smoking patch Chantix continues to generate lawsuits from users who allege ...
... ... Products and Specially-Constructed Wood Portable Floors. "Connor Sport Court Products Well Known For ... ... (CSCI) will provide more than 65,000 square feet of Sport Court® products and a ...
... ... star John Salley is now using and officially endorsing the innovative stem cell nutrition ... ... basketball star John Salley is now using and officially endorsing the innovative stem cell ...
Cached Medicine News:Health News:New Study Uses Adult Stem Cells in Effort to Save Limbs of Patients with Peripheral Arterial Disease 2Health News:New Study Uses Adult Stem Cells in Effort to Save Limbs of Patients with Peripheral Arterial Disease 3Health News:Health 'Bites': 8 Things You Didn't Know About Your Teeth 2Health News:South Carolina Attorney Says Legal Options Still Available To Those Harmed By Chantix 2Health News:South Carolina Attorney Says Legal Options Still Available To Those Harmed By Chantix 3Health News:Connor Sport Court Lays the Ground for NBA All-Star Jam Session Presented by Adidas 2Health News:Connor Sport Court Lays the Ground for NBA All-Star Jam Session Presented by Adidas 3Health News:Health & Sports: Former NBA Star John Salley Endorses STEMTech Stem Cell Nutrition Products 2Health News:Health & Sports: Former NBA Star John Salley Endorses STEMTech Stem Cell Nutrition Products 3
(Date:1/23/2015)... 2015  Pete Rose, baseball,s all-time hits leader, is the new ... Myoflex, Ducere Pharma has announced. "Pete,s a Hall ... have him on board with Myoflex," said Ducere Pharma Chief ... player who is known across all generations. The passion and ...
(Date:1/23/2015)... , Jan. 23, 2015  Now available for sale, The ... support that prevents ankle sprains by cushioning the ankle ... fits securely around the outside of any shoe type ... comfort while still offering protection against sprains. With customers ...
(Date:1/23/2015)... EAST SETAUKET, N.Y. , Jan. 23, 2015  Lixte Biotechnology ... sites where its Phase I trial of Lixte,s lead compound, ... 5 institutions. John S. Kovach , M.D., ... trial was planned to be completed at a single site. ...
Breaking Medicine Technology:Pete Rose bets on Myoflex to relieve aches and pains 2The Armor1 Ankle Roll Guard is the New Breakthrough Solution for Ankle Sprain Prevention! 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 3
... 8, 2011  Zimmer Holdings, Inc. (NYSE: ZMH ; ... announced the availability of its CLS® Brevius ™ ... United States.  This new technology enables surgeons to better ... for independent, intraoperative adjustments. "Following its introduction ...
... YORK, Dec. 8, 2011   IBM (NYSE: ... database of chemical data extracted from millions of patents ... Health . This contribution will allow researchers to more ... in drug discovery and support advanced cancer research. ...
Cached Medicine Technology:Zimmer Introduces New CLS® Brevius™ Hip Stem with Kinectiv® Technology in the United States 2Zimmer Introduces New CLS® Brevius™ Hip Stem with Kinectiv® Technology in the United States 3IBM Contributes Data to the National Institutes of Health to Speed Drug Discovery and Cancer Research Innovation 2IBM Contributes Data to the National Institutes of Health to Speed Drug Discovery and Cancer Research Innovation 3
To prevent retraction of the conjunctival cul-de-sacs without touching the cornea....
Bioceramic orbital implants insert easily into orbital socket and will not cling to surrounding tissue. Improved interconnectivity between pores enhances vascularization. Implants may be easily drill...
...
... Our perimeters are not restricted to ... limited applications. These are full field ... the only perimeters you'll ever need ... care possible. They also include ...
Medicine Products: