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A comparative medicine study by Penn vet identifies a new approach to combat viral infections
Date:11/9/2012

, providing clinical evidence that these drugs could be used to treat infection.

Fuchs said that what seemed like a drawback in the study that it couldn't be effectively modeled in mice ended up being a benefit, as naturally occurring diseases in animals such as cat and dogs more closely mimic many human diseases.

Because interferon is known to suppress tumors and help multiple sclerosis patients, the results of this study give the researchers optimism that PTP1B could be a target for anti-cancer and anti-autoimmune disease therapies.

As a next step, they plan to test the PTP1B inhibitors in a model of feline immunodeficiency virus, or the cat version of AIDS, to see if its virus-fighting capabilities can have an effect against that infection.


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Contact: Katherine Unger Baillie
kbaillie@upenn.edu
215-898-9194
University of Pennsylvania
Source:Eurekalert

Page: 1 2 3 4

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