Navigation Links
A 'brain wave' test for schizophrenia risk?
Date:5/17/2011

Philadelphia, PA 17 May 2011 There is a significant need for objective tests that could improve clinical prediction of future psychosis.

One strategy has been to determine whether physiologic measures that are abnormal in people diagnosed with schizophrenia might also be useful in estimating the risk for developing this illness. This is the strategy taken by German and Swiss researchers in the current issue of Biological Psychiatry.

They used electroencephalography (EEG), which measures the brain's electrical activity or "brain waves", to study the brain's response to commonly and rarely presented tones that differed in length.

When these rare "deviant" tones are presented to healthy people, the brain automatically generates a particular electrical wave called mismatch negativity, or MMN. People diagnosed with schizophrenia have reduced MMN.

In this new study, the researchers followed a group of people clinically at high risk for developing psychosis. They found that the individuals who went on to develop schizophrenia had smaller MMN than the subgroup who did not. This finding suggests that MMN might be useful in predicting the later development of schizophrenia.

"With this type of study, the devil is always in the details. How sensitive is MMN as a risk predictor? How reliable is it? How many people are mistakenly classified? How long of a follow-up period is necessary to make this test useful? Are there subgroups of individuals for whom this test is or is not reliable?" mused Dr. John Krystal, Editor of Biological Psychiatry. "If we hope to use this type of measure to guide research and even clinical interventions, then it has to be an extremely robust measure with respect to the issues that I just mentioned, among others. Yet, this is exactly the type of initial step that we need to move toward clinically meaningful biological tests."

First author Dr. Mitja Bodatsch agreed, adding that "integration of both biological and clinical measures into multidimensional models might be the crucial next step forward to improve risk staging in psychiatry."


'/>"/>

Contact: Chris J. Pfister
C.Pfister@elsevier.com
215-239-3266
Elsevier
Source:Eurekalert

Related medicine news :

1. Brain Surgery for Mary Tyler Moore to Remove Benign Tumor
2. Ecstasy Use May Make Brain Less Efficient
3. Einstein secures $11 million to continue research on brain aging and Alzheimers disease
4. The brain performs visual search near optimally
5. Whats Good for Your Heart Is Good for Your Brain
6. Single Gene Linked to Evolution of Human Brain
7. Most Leukemia Patients Recover From Chemo Brain After Transplant: Study
8. Sex, Coffee May Boost Risk of Brain Aneurysm Rupture: Study
9. Scientists afflict computers with schizophrenia to better understand the human brain
10. Can Hormone Therapy or the Pill Prevent Brain Aneurysms?
11. New route to map brain fat
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... (PRWEB) , ... March 24, 2017 , ... ... Center, Sedona, Arizona’s Premier Center for Shamanic Healing and Spiritual Awakening, proudly ... Delgado, June 9--24, 2017. This sacred and spiritual journey during the Summer ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... they are now offering treatments for sleep apnea and TMJ at their office. ... Sleep apnea , specifically the obstructive type, is increasingly being treated at dental ...
(Date:3/24/2017)... ... 24, 2017 , ... Viewers who like to educate themselves on current issues ... goods, services, and societal issues tend to appreciate and love the "Informed" series, hosted ... utilizing running events for causes around the world. , Running for charity ...
(Date:3/24/2017)... ... March 24, 2017 , ... Judy ... Reiki™ Master in Frederick, MD. Judy says, “I am passionate about sharing Reiki ... often a very difficult and challenging time.” , A Certified Medical Reiki™ Master ...
(Date:3/24/2017)... ... March 24, 2017 , ... “Vintage and Harvest A Cultivation ... and college Bible teacher residing in North Carolina with his wife, Anna Marie. He ... them with six grandchildren. David is also the author of “Shadow and Substance.” , ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... Research and Markets has announced the addition of the "Microplate ... offering. ... separate comprehensive analytics for the US, Canada , ... , Latin America , and Rest of World. ... Also, a six-year historic analysis is provided for these markets. Market data ...
(Date:3/24/2017)... 23, 2017  HealthMine surveys with 9,250 insured consumers ... health plan members want help from their plans in ... in their health, 2) help closing gaps in care, ... health and 5) relevant, real-time guidance. Meeting these needs ... costs. A Reason to Stay ...
(Date:3/24/2017)... YORK and GENEVA , ... announced on World Tuberculosis Day revitalizes efforts to develop ... On World Tuberculosis Day, TB Alliance and ... for the clinical development of sutezolid, an antibiotic drug ... sublicense pertains to the development of sutezolid in combination ...
Breaking Medicine Technology: