Navigation Links
A better test to detect DNA for diagnosing diease, investigating crimes
Date:8/26/2009

Researchers in Singapore are reporting development of a new electronic sensor that shows promise as a faster, less expensive, and more practical alternative than tests now used to detect DNA. Such tests are done for criminal investigation, disease diagnosis, and other purposes. The new lab-on-a-chip test could lead to wider, more convenient use of DNA testing, the researchers say. Their study is scheduled for the Sept. 2 issue of the Journal of the American Chemical Society, a weekly publication.

In the new study, Zhiqiang Gao and colleagues note that current methods for detecting DNA involve the used of the polymerase chain reaction (PCR). This technique "amplifies" or makes multiple copies of trace amounts of DNA, much as a photocopier produces multiple copies of documents, in order to detect the genetic material more easily. The amplification step is one reason why tests involving PCR can be too expensive, cumbersome, and imprecise for wider use.

The researchers describe development of a so-called "nanogap sensor" that appears to overcome those obstacles. The process uses a pair of micro-sized metal electrodes separated by a nanogap, 1/50,000 the width of a human hair, in combination with special chemical probes, to capture tiny segments of DNA. The newly formed "circuit" then translates the presence of DNA into an electrical signal so that it can be measured by a computer. In laboratory tests, the sensor showed "excellent" sensitivity at detecting trace amounts of human DNA and may eliminate the need for DNA amplification altogether, the researchers say.


'/>"/>

Contact: Michael Woods
m_woods@acs.org
202-872-6293
American Chemical Society
Source:Eurekalert  

Page: 1

Related medicine news :

1. Comparative Effectiveness Research Study in Mayo Clinic Proceedings Demonstrated Asthma Patients Had Better Overall Results with Oral Controllers than Inhaled Products
2. The Berry Truth: Cystex Know Your Bladder Better Video Explains Why Cranberries Are Great for UTI Prevention, But Not for Treatment
3. Why Weight for a Better Body?
4. New treatments offer better survival and fresh challenges in colorectal cancer
5. Better Pap Smear Follow-Up Needed Among Lower-Income Women
6. Nonprofit nursing homes provide better care, major study finds
7. New Omega-3 Blood Test: A Better Predictor of Coronary Heart Disease Than Cholesterol
8. Endoscopy within 24 hours shows better outcomes in elderly with peptic ulcer bleeding
9. Surprise! Better Sleep with Gene-Eden(R), an Antiviral Supplement
10. Limb-sparing surgery may not provide better quality of life than amputation for bone cancer patients
11. Not-For-Profit Nursing Homes Fare Better in Studies
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A better test to detect DNA for diagnosing diease, investigating crimes
(Date:5/4/2016)... ... 2016 , ... Over 40 athletic trainer’s (ATs) and athletic training students (ATSs) ... “Hike to Harrisburg” advocacy day. The annual lobbying effort is a collaboration between ... The goal for the day was to educate the elected legislators and the public ...
(Date:5/4/2016)... ... May 04, 2016 , ... Vasont Systems, a ... Integrator (VUI) extension supports the latest release of Adobe FrameMaker, Release 2015. The ... the process of creating, editing and storing XML. , The VUI ...
(Date:5/3/2016)... , ... May 04, 2016 , ... ... cancer. That message is reaching the global health community through expanding activities that ... burden of cancer in the resource-limited countries. , In support of ...
(Date:5/3/2016)... ... May 03, 2016 , ... ... patients report dissatisfaction with numerous issues related to medical care in the hospital ... and poor bedside manner from hospital staff. Commenting on this article, the founder ...
(Date:5/3/2016)... ... ... Sue Desmond-Hellmann, chief executive officer of the Bill & Melinda Gates Foundation, ... in her keynote address at Georgia State University’s spring commencement on Saturday, ... experience as a scientist, physician and executive, Desmond-Hellmann leads the Gates Foundation’s efforts to ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... Global and Chinese Surgical ... overview of the industry that covers definition, applications ... report explores into the international and Chinese players ... Surgical Mesh market spread across 150 pages providing ... is available at http://www.reportsnreports.com/reports/470569-global-and-chinese-surgical-mesh-industry-2016-market-research-report.html . ...
(Date:5/2/2016)...  Deerfield announced today it led the $44.5 ... Graybug Vision is an early stage pharmaceutical company ... for ocular diseases including wet age-related macular degeneration ... developed at Johns Hopkins University and has been ... Graybug Vision is developing ophthalmology products enabling ...
(Date:4/29/2016)... Calif. , April 29, 2016  In ... is projected to shift from systems dependent on ... all types of modality CRT Medical monitors and ... there are a host of foreseeable benefits to ... concern; will existing modalities have to be replaced ...
Breaking Medicine Technology: