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A*STAR scientist Alex Matter awarded prestigious Szent-Györgyi Prize for progress in cancer
Date:4/5/2013

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5. Chairman of A*STAR, Mr. Lim Chuan Poh said, "The phenomenal success of Glivec is a testament to the profound impact that Alex's work has on the approach of cancer drug development. He truly deserves this honour and I extend my heartiest congratulations to him. With his deep expertise in drug discovery, Alex's first-hand experience and in-depth knowledge will guide and mentor Singapore's next generation of scientists in the process of drug discovery and development to meet increasingly difficult healthcare challenges."

6. With a primary mission of translating early stage scientific discoveries into useful clinical applications, ETC is actively involved in collaborations with both public and private sector organisations. Under Professor Matter's leadership, ETC signed a license agreement with Tan Tock Seng Hospital and local company AITbiotech in May last year to market a made-in-Singapore H5N1 bird flu diagnostic kit[2]. The kit allows doctors to rapidly detect all existing strains in a single test with nearly 100% accuracy, within just a few hours.

7. Presently, ETC is working on pre-clinical drug candidates specifically for CML patients who have developed resistance to imatinib mesylate. Carried out in cooperation with Duke-NUS, the drug is expected to enter the clinical trial stage around middle of 2014.

8. Meanwhile, ETC is in the early stages of developing a flu vaccine with A*STAR's SIgN (Singapore Immunology Network), D3 (Drug Discovery and Development) [3], Duke-NUS, DSO and several private companies. By the middle of 2013, the consortium will be able to determine if it is ready for Phase I clinical trials for proof-of-concept in humans. If successful, this flu vaccine will play a critical role in national preparedness as it will ensure that Singaporeans will have access to the vaccine in times of a flu pandemic.

9. Professor Matter has lived in Si
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Contact: Dr. Sarah Chang
chang_kai_chen@a-star.edu.sg
656-826-6442
Agency for Science, Technology and Research (A*STAR), Singapore
Source:Eurekalert

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