Navigation Links
A*STAR partners Roche to develop new cancer therapeutics
Date:7/14/2014

SingaporeA*STAR's Bioprocessing Technology Institute (BTI) has entered into an agreement with one of the world's largest pharmaceutical company, Roche, to identify novel drug candidates for the detection and treatment of cancer. The partnership brings together BTI's capabilities in novel antibody discovery and Roche's expertise in developing monoclonal antibody (mAbs) therapeutics, opening up the possibility of improved treatment for cancer, a leading cause of death worldwide.

The collaboration makes use of BTI's discovery of a new mechanism where antibodies can directly target and destroy cancer cells, which has the potential for an entirely new class of cancer treatment. Cancer cells may be distinguished from normal cells by their elevated levels of sugar on the cell surface. The mAbs discovered and generated by BTI are able to recognise these sugar targets and allow more accurate identification of cancer cells as compared to traditional antibodies that only target proteins. mAbs generated by BTI are also unique in having a novel mechanism of action; they cause pores to form on the surface of cancer cells, leading to cell degradation and the eventual death of these diseased cells.

Dr Andre Choo, Principal Scientist at BTI and lead investigator for the project, said, "It is exciting to be able to generate a new class of mAbs that can specifically recognise sugars and lead to rapid death of diseased cells. This opens up new strategies to target and kill cancer cells."

Based on this discovery, scientists from BTI have developed a pipeline of mAbs for major cancers found in Singapore. The partnership with Roche will allow new diagnostic tests and cancer treatments to be developed more quickly and to be brought earlier to patient care. Such treatments could complement and augment existing cancer drugs and result in more effective and safer treatments for cancer patients.

Prof Lam Kong Peng, Executive Director of BTI,
'/>"/>

Contact: Vanessa Loh
vanessa_loh@a-star.edu.sg
Biomedical Sciences Institutes (BMSI)
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. A*STAR scientists discover switch to boost anti-viral response to fight infectious diseases
2. Fruit flies light the way for A*STAR scientists to pinpoint genetic changes that spell cancer
3. A*STAR scientists identify potential drug target for inflammatory diseases including cancers
4. Singapore scientists led by A*STARs GIS identify 4 mechanisms that contribute to gastric cancers
5. A*STAR scientists discover switch critical to wound healing
6. A*STAR scientist Alex Matter awarded prestigious Szent-Györgyi Prize for progress in cancer
7. A*STAR scientist wins European Molecular Biology Organization Young Investigator award
8. A*STAR scientists uncover potential drug target to nip cancer in the bud
9. A*STAR scientists bring to light mechanism of drug for infections
10. Women With Older Partners More Often Admitted to Nursing Homes
11. University of Houston Graduate College of Social Work announces partnership with MD Anderson
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A*STAR partners Roche to develop new cancer therapeutics
(Date:3/1/2015)... 01, 2015 Researchers say working around ... many sheet metal workers contract malignant mesothelioma. Surviving Mesothelioma ... on its website. Click here to read it ... Research and Training monitored 17,345 sheet metal workers from ... of them died of mesothelioma or another asbestos-related ...
(Date:3/1/2015)... Indianapolis, Indiana (PRWEB) March 01, 2015 ... Indiana statewide Network Service Provider, announces NewWays Networking, ... provider. “By working with IFN, NewWays is ... to meet client’s demand for Internet bandwidth in ... Owner/Manager. , According to Cory Childs IFN ...
(Date:3/1/2015)... CrossFit Attollo is a CrossFit gym located in Vancouver ... to new members. Now through the end of March ... will receive their fourth month half off. , ... The three month contract is only $264, dropping the price ... comes in at only $55. The special saves new members ...
(Date:2/28/2015)... In a recent episode of SCI TV ... Athlete Development Services and Consultancy talks with Joshua ... development and player engagement during and after their careers. ... face and how off-field activities are a critical component ... in athlete development issues while in graduate school coaching ...
(Date:2/28/2015)... 2015 The Classic Denture Center ... new special. Throughout all of March patients can ... This service can help overall mouth health ... Patients may notice certain symptoms that suggest the denture ... symptoms include: , 1.    Pain, clicking, and popping in the ...
Breaking Medicine News(10 mins):Health News:New Study Finds Indirect Asbestos Exposure Can Raise Mesothelioma Risk for Sheet Metal Workers, According to Surviving Mesothelioma 2Health News:NewWays Networking Selects Indiana Fiber Network, LLC as Fiber Transport Provider 2Health News:CrossFit Gym in Vancouver WA Offers Spring Special 2Health News:SCI TV Covers Athlete Development with Duncan Fletcher 2Health News:SCI TV Covers Athlete Development with Duncan Fletcher 3Health News:Classic Denture Center in Portland Oregon is Offering March Discount 2
... Corresponding Journal of Nutrition supplement urges health professionals to ... to be published in the June issue of the ... and the general public to stop demonizing high fructose ... rethink the myths about high fructose corn syrup,s impact ...
... NAS to Store Public Database of Genomic and Trait Data ... Isilon(R) Systems (Nasdaq: ISLN ), the ... Personal Genome Project (PGP) has deployed Isilon ... for an unprecedented research project aimed at transforming the use ...
... Keeping Up on Developments in the Long term Care Insurance ... interest in long term care insurance need no longer dig ... pros do: have the information come to them, in bits ... secrets," says Jonas Roeser, Senior Vice President of Marketing & ...
... on lung cancer and mesothelioma specialists into one of ... asbestos-related diseases. Our searchable, easy-to-use database contains doctor profiles ... it easy for residents of California or New York, ... in their area. , ...
... medical malpractice challenge by introducing low tech solution ... introduces standardized shift reporting and note taking to ... to day tasks.RNReport Card is more efficient by ... It fits conveniently in the pocket of your ...
... Packard Children,s Hospital and the Stanford University School of ... deadly and mysterious bowel disease that strikes medically fragile ... understanding of the disease and its medical management, and ... major killer of children and young adults. , The ...
Cached Medicine News:Health News:Experts Lay to Rest Long-Held Misconceptions About High Fructose Corn Syrup at ILSI-USDA Workshop 2Health News:Experts Lay to Rest Long-Held Misconceptions About High Fructose Corn Syrup at ILSI-USDA Workshop 3Health News:The Personal Genome Project Deploys Isilon IQ Storage to Transform Genomic Research 2Health News:The Personal Genome Project Deploys Isilon IQ Storage to Transform Genomic Research 3Health News:Long Term Care Alerting Methods Revealed by Industry Leaders 2Health News:MesotheliomaHelp.net Announces Expanded Information on Lung Cancer and Mesothelioma Specialists 2Health News:MesotheliomaHelp.net Announces Expanded Information on Lung Cancer and Mesothelioma Specialists 3Health News:RN Sisters Bring Low-Tech Innovations to New Nurses and Nursing Students 2Health News:Packard/Stanford study suggests two causes for bowel disease in infants 2Health News:Packard/Stanford study suggests two causes for bowel disease in infants 3
(Date:2/26/2015)... 2015 RnRMarketResearch.com adds Corneal ... report to its store. This report p provides ... The report "Corneal Ulcers - Pipeline Review, H2 ... for Corneal Ulcers. Corneal Ulcers are primarily result ... viral infections & fungal infections. The symptoms of ...
(Date:2/26/2015)... , Feb. 26, 2015  Today the ... The psychological and physical side effects of pain ... opioid painkillers, such as Vicodin and Oxycontin, are safer ... Americans overdose on prescription painkillers than on heroin and ... and CEO of NSC. "Yet, these medications are marketed ...
(Date:2/26/2015)... WASHINGTON , Feb. 26, 2015  Mail-service ... consumers, employers and government health plans ... research released by the Pharmaceutical Care Management Association ... specialty drugs offers one of the easiest ways ... CEO Mark Merritt . "Policymakers should resist ...
Breaking Medicine Technology:Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 2Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 3Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 4Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 5National Safety Council: Opioid prescription painkillers have hidden, deadly side effects 2PCMA: Report Shows High-Tech Specialty and Mail-Service Pharmacies Will Reduce Costs for Texas Employers, Consumers and Public Programs by $23.3 Billion 2
... Cumberland Pharmaceuticals Inc.(Nasdaq: CPIX ) today announced the ... of the supplemental new drug application (sNDA) for the use ... acute liver failure. The review has been extended by three ... (PDUFA) goal date in December 2010. "We ...
... 20 The European Patent Office ("EPO") Board ... to uphold European Patent No. EP 1307131 for ... http://photos.prnewswire.com/prnh/20061011/SFW044LOGO ) (Logo: http://www.newscom.com/cgi-bin/prnh/20061011/SFW044LOGO ... 26th, keeps the GlideScope patent in force in ...
Cached Medicine Technology:Cumberland Pharmaceuticals Announces Extension of FDA Review of Acetadote® Supplemental New Drug Application 2Cumberland Pharmaceuticals Announces Extension of FDA Review of Acetadote® Supplemental New Drug Application 3European Patent Office Upholds GlideScope® Video Laryngoscope Patent 2
14mm from Mid-Screw to Tip, Slightly Curved, Sharp Tips; overall length 110mm; Stainless Steel....
9mm Curved Blades with Sharp Pointed Tips; overall length 90mm; Stainless Steel....
4 Gently Curved, Prongs, 5mm Extended, Stainless Steel Tip; with Titanium Handle....
12mm from bend to 0.12mm 1x2 teeth; In Titanium....
Medicine Products: