Navigation Links
A Protein Links Alzheimer's, Down Syndrome
Date:5/20/2010

Amyloid-beta accumulates in eyes of Down-affected patients, spurring cataracts, study finds

THURSDAY, May 20 (HealthDay News) -- Researchers say a kind of protein that clogs the brain in Alzheimer's disease also accumulates in the eyes of Down syndrome patients and causes cataracts.

The finding is leading the researchers to develop an eye test for early signs of Alzheimer's in both disorders.

"People with Down syndrome develop symptoms of Alzheimer's-type dementia often by the age of 30," said study co-author Dr. Lee E. Goldstein, associate professor at Boston University School of Medicine, in a statement. "This is because they have an extra copy of a key Alzheimer's gene that leads to increased amyloid-beta accumulation in the brain. We discovered that this same protein starts to accumulate very early in the lens of the eye, even in children."

"The results are striking," added Dr. David G. Hunter, ophthalmologist-in-chief at Children's Hospital Boston and vice chairman of the department of ophthalmology at Harvard Medical School. "We have known that these cataracts are prevalent in people with Down syndrome and are sometimes seen at birth, but we never knew how they were related to the disorder. Now we know. These distinctive cataracts appear only in people with advanced Alzheimer's disease and much earlier in Down syndrome."

Goldstein said the team is developing an eye scanner to measure amyloid-beta, the protein in question, in the lens. "This approach may provide a way for early detection and monitoring of related pathology in the brain. Effective treatments for the brain disease in Down syndrome and Alzheimer's disease are on the horizon, and early detection is the key for successful intervention."

The findings were reported in the May 20 issue of the journal PLoS One and presented at the recent meeting of the Association for Research in Vision and Ophthalmology in Fort Lauderdale.
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Scientists find protein spurs spread of prostate cancer
2. System that predicts protein structures could help researchers design drugs
3. Without this protein, embryonic development halts
4. Study finds key protein controls T-cell proliferation
5. A century-old puzzle comes together: Scientists ID potential protein trigger in lung disease sarcoidosis
6. The effect of dietary supplements, acids and animal protein on gastrointestinal disorders
7. A single protein regulates 2 immune pathways
8. Alzheimers memory problems originate with protein clumps floating in the brain, not amyloid plaques
9. Biosensor chip enables high-sensitivity protein analysis for disease diagnosis
10. Protein plays a critical role in the development of aggressive breast cancer
11. Structure of inner-ear protein is key to both hearing and inherited deafness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/1/2015)... It is the meat that has become an ... wrapped around other foods, infused into cocktails and even made ... the gateway meat for vegetarians and the perfect food. To ... Meat Institute (NAMI) has developed a new Ultimate Guide ... bacon processing plant and companion brochure with ...
(Date:4/1/2015)... 2015 Pricing Healthcare has added facilities ... bring coverage to a third of all US states. ... Kansas, and Iowa, and the first dedicated eye center in the ... TX was also added. , In addition, the site reached a ... interest in the platform continue to grow across the country. , ...
(Date:4/1/2015)... WA (PRWEB) April 01, 2015 With so ... been forced to spend much of their time indoors. When ... maintain clean, healthy air. The latest article from Clean ... the air quality in their homes. , One of ... is for homeowners to keep houseplants. The article states that, ...
(Date:4/1/2015)... Middleburg, VA (PRWEB) April 01, 2015 ... rewarding habit to form. Its rewards are inestimable." - ... recognizes outstanding individuals in the water resources profession. ... now open. Please consider nominating yourself, a colleague, or ... May 1, 2015. Learn more about the AWRA Awards ...
(Date:4/1/2015)... TX (PRWEB) April 01, 2015 Decora Preset ... is now available on ‘The Hardware City.’ The product helps ... to set a time and the related electronic device is ... a representative of the company said, “We are glad that ... Now customers can buy Countdown Timer Switch in just a ...
Breaking Medicine News(10 mins):Health News:New Ultimate Guide to Bacon Video Provides Inside Look at How Bacon is Made 2Health News:PricingHealthcare.com Adds Facilities in 5 States, Hits 10,000 Monthly Users Milestone 2Health News:PricingHealthcare.com Adds Facilities in 5 States, Hits 10,000 Monthly Users Milestone 3Health News:3 Simple Ways to Improve Home Air Quality Listed by Clean Crawls in Latest Article 2Health News:Nominations Sought for National Water Resources Awards and Student Scholarships 2Health News:Nominations Sought for National Water Resources Awards and Student Scholarships 3Health News:Leviton Decora Preset 30 Minute Countdown Timer Available On TheHardwareCity.com 2
... AIDS Hospice Now Serves as HIV/AIDS Care Hub, ... its filing of a lawsuit against the City of ... breach of contract and for a,"judicial determination" regarding the ... the US, largest non-profit HIV/AIDS,healthcare, research, prevention and education ...
... food labels , , SUNDAY, Feb. 24 (HealthDay News) -- ... can improve your heart health, but also your overall ... to be guided toward healthier choices for your heart, ... Cathy Fitzgerald, registered dietitian with MFit, the University of ...
... to the Lesbian, Gay, Bisexual and Transgender ... (LGBT) Movement By Early Microsoft Employee Pride ... Pride Foundation of Seattle is honored,to announce the establishment ... Mr. Weiland,s gift of $65 million is the largest single ...
... likely to have an attack, study finds , , SATURDAY, ... factors and more barriers to health care may be among ... States than in Europe, a new study suggests. , Researchers ... and 30,120 people in 11 European countries, and found that ...
... improving patient safety and enabling better information management for ... caregivers and patients., ORLANDO, Fla., Feb. 22 , ... (HIMSS) 2008 Conference & Exhibition, ... showcase in its booth (No. 2247) new solutions designed ...
... users diagnosed almost 7 years earlier than nonsmokers , , ... with significant exposure to secondhand smoke should start getting ... than the current recommended age of 50, a new ... Medical Center in New York analyzed the cases of ...
Cached Medicine News:Health News:AHF Sues L.A. Housing Dept. to Prevent Closure of AIDS Site 2Health News:AHF Sues L.A. Housing Dept. to Prevent Closure of AIDS Site 3Health News:AHF Sues L.A. Housing Dept. to Prevent Closure of AIDS Site 4Health News:AHF Sues L.A. Housing Dept. to Prevent Closure of AIDS Site 5Health News:How to Be Heart Smart at the Supermarket 2Health News:Ric Weiland Leaves $65 Million to Support Gay Rights and HIV/AIDS Organizations 2Health News:Ric Weiland Leaves $65 Million to Support Gay Rights and HIV/AIDS Organizations 3Health News:More Risk Factors, Less Access to Care Behind Higher Stroke Rates in U.S. 2Health News:Microsoft to Showcase Innovative Solutions for Healthcare Providers and Consumers at HIMSS 2008 Annual Conference & Exhibition 2Health News:Microsoft to Showcase Innovative Solutions for Healthcare Providers and Consumers at HIMSS 2008 Annual Conference & Exhibition 3Health News:Earlier Colon Cancer Screens Urged for Smokers 2
(Date:3/31/2015)... , March 31, 2015 UHC has released ... use of medical devices based on cost and quality ... preference items (PPIs). The study examined utilization of PPIs—which ... supply expenses 1 —at 10 academic medical centers, focusing ... and cardiac valves. The study, begun ...
(Date:3/31/2015)... , March 31, 2015 /CNW/ - Today, the Honourable Rona ... and animal health organizations to discuss the Government of ... resistance (AMR). The roundtable provided an ... to share their priorities and discuss roles and responsibilities ... ensuring their optimal use (also known as antimicrobial stewardship) ...
(Date:3/31/2015)... 31, 2015 Mauna Kea Technologies ... laser endomicroscopy platform, today announced the set-up of an ... hospital center). The CHU de Grenoble is now the ... propose to its gastroenterology, interventional pulmonology and urology patients ... standard of care thanks to the endomicroscopy technology developed ...
Breaking Medicine Technology:UHC Study: Variations in Use of Physician Preference Items Affect Patient Outcomes and Costs 2UHC Study: Variations in Use of Physician Preference Items Affect Patient Outcomes and Costs 3Government of Canada hosts roundtable discussion to advance Canada's work on antimicrobial resistance 2Government of Canada hosts roundtable discussion to advance Canada's work on antimicrobial resistance 3Government of Canada hosts roundtable discussion to advance Canada's work on antimicrobial resistance 4Grenoble University Hospital First Hospital in France to set up a Multidisciplinary Optical Biopsy Program With the Cellvizio Endomicroscopy Platform 2Grenoble University Hospital First Hospital in France to set up a Multidisciplinary Optical Biopsy Program With the Cellvizio Endomicroscopy Platform 3
Inquire...
Inquire...
Flextend is a hydrocolloid skin barrier that is designed to be the most resistant to discharge and is the barrier of choice for urostomies and high output ileosotomies....
Premier pouches provide the ultimate in skin protection with our long wearing Flextend skin barriers and superior comfort with our soft and silky ComfortWear panels....
Medicine Products: