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A Phase III Alzheimer's Drug Increases Levels of Beta Amyloid in the Brain - But Still Provides Benefits
Date:7/14/2009

VIENNA, July 15 /PRNewswire-USNewswire/ -- New insights into how a Phase III Alzheimer's drug might work were among the advances in potential therapies targeting two abnormal brain proteins - beta amyloid and phosphorylated tau - that were reported today at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD 2009) in Vienna.

(Logo: http://www.newscom.com/cgi-bin/prnh/20090529/ICADLOGO )

Scientists also reported on how clinicians view and treat mild cognitive impairment (MCI), a research category used to define the state between normal aging and Alzheimer's, that is now being used widely in clinical practice.

"There are now more than 5 million people living with Alzheimer's disease in the United States. The cost of caring for people who now have Alzheimer's, and those who will get it in the next few years, will bankrupt the healthcare system and devastate Medicare and Medicaid," said Ralph Nixon, PhD, MD, vice chair of the Alzheimer's Association Medical & Scientific Advisory Council.

"But, as these studies and many hundreds more reported at ICAD 2009 show, there is hope. There are currently dozens of drugs in Phase II and III clinical trials for Alzheimer's. This, combined with advancements in diagnostic tools, has the potential to change the landscape of Alzheimer's in our lifetime. How fast we get there depends completely on the investment in research. We need more government and private dollars for Alzheimer's research now to capitalize on the progress we've made in the last decade," Nixon added.

Surprisingly, Dimebolin Increases Brain Beta Amyloid in Alzheimer's Mouse Models

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SOURCE Alzheimer's Association
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