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A Drug That Carries a Lower Risk of Weight Gain Than AstraZeneca's Seroquel and Has Antimanic and Antidepressant Effects Would Earn a 30 Percent Patient Share in Bipolar Disorder Treatment
Date:4/22/2008

Seroquel's Successor, Seroquel XR, Will Earn a 16 Percent Patient Share in

the Bipolar Disorder Market by 2016, According to a New Report from

Decision Resources

WALTHAM, Mass., April 22 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that a therapy that carries a lower risk of weight gain than AstraZeneca's Seroquel and has both antimanic and antidepressant effects would earn a 30 percent patient share in the treatment of bipolar disorder, according to surveyed psychiatrists.

The new report entitled Bipolar Disorder: Although Bipolar Mania Is a Crowded Market, Physicians Continue to Demand Better Treatment finds that surveyed psychiatrists indicate that they would prescribe AstraZeneca's Seroquel XR to 20 percent of their bipolar disorder patients, following its approval for the indication in 2009. As a result, Seroquel XR is forecasted to earn a 16 percent patient share in the U.S. bipolar disorder market in 2016.

The report also finds that Seroquel XR will earn gold-standard status for treatment of bipolar disorder in 2011 as interviewed psychiatrists indicate that Seroquel XR's delivery profile -- once-daily dosing -- will be marginally superior to that of Seroquel immediate-release. Although surveyed psychiatrists indicated that lithium and Eli Lilly's Zyprexa have advantages in efficacy, lithium and Zyprexa have disadvantages in safety, tolerability and/or delivery when compared to Seroquel.

"Interviewed psychiatrists report that Seroquel can sometimes require twice-daily dosing for sustained efficacy," said Kate Hohenberg, director at Decision Resources. "As a result, Seroquel XR narrowly edges out its parent compound to become the new gold standard because of its incremental advantage in delivery."

About the Report

Bipolar Disorder: Although Bipolar Mania Is a Crowded Market, Phy
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SOURCE Decision Resources
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