Navigation Links
A Drop of Blood May Help Assess Cancer Therapy
Date:4/13/2009

Technique could one day quickly detect if treatment is working, study suggests

MONDAY, April 13 (HealthDay News) -- A specialized technique that can detect subtle changes in cancer cells contained in a drop of blood or a tiny piece of tissue may one day be used by doctors to better assess how cancers are responding to treatment, say U.S. researchers.

"Currently, we don't know what's going on in a patient's actual tumor cells when a treatment is given. The standard way we measure if a treatment is working is to wait several weeks to see if the tumor mass shrinks. It would really be a leap forward if we could detect what is happening at the cellular level," lead author Dr. Alice Fan, a clinical instructor in the oncology division at the Stanford University School of Medicine in California, said in a school news release.

"This technology allows us to analyze cancer-associated proteins on a very small scale," senior study author Dr. Dean Felsher, an associate professor of medicine and of pathology, said in the news release. "Not only can we detect picogram levels -- one-trillionth of a gram -- of protein, but we can also see very subtle changes in the ways the protein is modified."

Variations in the way a protein is modified can affect how it functions in tumor progression. Cancer cells can dodge common therapies by changing their levels of protein expression and degrees of modification, according to background information in the news release.

The ability to continuously analyze small samples from cancer patients undergoing treatment may help doctors identify "rogue" cells before they can create a more treatment-resistant tumor. This technology could also help identify patients with cancers that are resistant to standard treatments.

Tests showed the technique was effective in samples of blood cancers, and the researchers hope it will also help track solid tumors. The Stanford team collaborated with researchers from Cell Biosciences, which makes the machine used in the study.

The study is in the April 12 online issue of the journal Nature Medicine.

More information

The U.S. National Cancer Institute has more information about cancer.



-- Robert Preidt



SOURCE: Stanford University, news release, April 12, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Cord Blood America Announces First Storage Sale in Germany; Commitment to Expansion
2. Blood tests reveal tobacco smoke residues in non-smoking New Yorkers
3. Growth factor TGF-B helps maintain health of retinal blood vessels
4. Global Med Technologies(R), Inc. Licenses Its Leading European Blood and Laboratory Solutions to Homburg, Germany Clinic Blood Center
5. CVS Caremark Study Documents Changes in Prescription Drug Use to Treat High Blood Pressure, High Cholesterol and Diabetes in Children and Adolescents
6. More U.S. Kids Taking Diabetes, Blood Pressure Drugs
7. Stem cell therapy grows new blood vessels
8. Cord Blood Announces $1.75 Million Reduction in Long Term Debt
9. Arthritis Trial Leads to Potential Cure for High Blood Pressure
10. World-first high blood pressure treatment trialled in Melbourne
11. Haemonetics Bolsters Blood Bank Information Management Portfolio With Acquisition of Altivation Software
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A Drop of Blood May Help Assess Cancer Therapy
(Date:6/27/2016)... California (PRWEB) , ... June 27, 2016 , ... "FCPX ... fully customizable inside of Final Cut Pro X," said Christina Austin - CEO of ... unique style. Final Cut Pro X users can now reveal the media ...
(Date:6/26/2016)... ... 2016 , ... Quality metrics are proliferating in cancer care, and are derived ... eye of the beholder, according to experts who offered insights and commentary in the ... Care. For the full issue, click here . , For the American Society ...
(Date:6/26/2016)... ... June 26, 2016 , ... ... have been diagnosed with endometriosis. These women need a treatment plan to not ... comprehensive approach that can help for preservation of fertility and ultimately achieving a ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency ... named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. ... Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director ...
(Date:6/24/2016)... Los Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... plastic surgery procedures that most people are unfamiliar with. The article goes on to ... known procedures, but also many of these less common operations such as calf and ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Any dentist who ... challenges of the current process. Many of them do not ... the technical difficulties and high laboratory costs involved. And those ... offer it at such a high cost that the majority ... Dr. Parsa Zadeh , founder of Dental ...
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: RO, ... clearance for its Elecsys BRAHMS PCT (procalcitonin) assay as ... or septic shock. With this clearance, Roche is the ... fully integrated solution for sepsis risk assessment and management. ... bacterial infection and PCT levels in blood can aid ...
(Date:6/23/2016)... -- Research and Markets has announced the addition ... to their offering. The ... commercial environment for MedImmune to enter. The US ageing population ... to drive considerable growth for effective anti-influenza medications. The introduction ... considerably, but development is still in its infancy. ...
Breaking Medicine Technology: