Navigation Links
A Chinese medicine compound has satisfactory anti-cancer effects on hepatocellular carcinoma
Date:10/15/2007

Traditional Chinese medicine is world renowned. It has supernatural effects on some diseases, but the reason is still unknown. One such article was recently reported in the November 7 issue of the World Journal of Gastroenterology dealing with the great significance of a Chinese medicinal compound, delisheng, for the therapy of HCC and its neoteric research method. The research team was led by Dr. Ke-Jun Nan from The First Affiliated Hospital of The School of Medicine of Xian Jiaotong University, China. This research will undoubtedly bring comfort to many researchers and patients.

HCC is a highly malignant tumor with a very high morbidity and mortality. Despite extensive efforts by many investigators, systemic chemotherapy for HCC has been quite ineffective. Delisheng is a Chinese medicinal compound and is often used in conjunction with chemotherapy for HCC, with satisfactory results. The researchers tried to establish the mechanisms for these effects of delisheng on HCC.

Three-dimensional cell culture has been widely used for studying the various molecular processes, because spheroids mimic solid tumors more closely than monolayers. Therefore, the use of three-dimensional culture provides a model for the development of anti-cancer drugs. In this study, cells were cultured with a liquid overlay technique. After the formation of multicellular spheroids, they used the model to perform their experiments.

One conclusion reported by the investigators is that three-dimensional cell culture is suitable for the study of a traditional Chinese medicinal compound, and this may help other researchers to find a better model for drug development. Another interesting conclusion is that delisheng had satisfactory anti-cancer effects on HCC, and these were associated with the up-regulation of endostatin. This was made possible by one of delishengs components, ginseng, and this may provide a new method of therapy for HCC.

Thus three-dimensional cell culture has been widely used for studying the various molecular processes and the development of therapy in recent years; this is the first reported finding in which the model can be used for studying traditional Chinese medicine. Furthermore, the view that the satisfactory effects of delisheng were associated with the up-regulation of endostatin made possible by ginseng might inspire other researchers.

The results of this study suggest a promising future for many researchers and HCC patients. First, it provides a new model to study traditional Chinese medicine. Second, it introduces the Chinese medicinal compound delisheng and indicates its further applications.


'/>"/>

Contact: You-De Chang
y.d.chang@wjgnet.com
0086-108-538-1892
World Journal of Gastroenterology
Source:Eurekalert

Related medicine news :

1. Chinese paracetamol may be slapped with dumping duty
2. Chinese Girl To Undergo Face Transplant Surgery
3. Stay young the Chinese way
4. A Chinese herb kills cancer cells
5. Chinese herbal remedies aids in cancer treatment
6. Prohibited diet medicine found in Chinese herbs
7. Global Outbreak Of Bird Flu Warning By Chinese Scientist
8. Japanese And Chinese Pharmaceutical Companies Join Together In Drug Testing
9. Unscrupulous Chinese Medicine traders putting lives at risk
10. Chinese City Suspends Water Supply Fearing Pollution
11. Running Water Restored In Chinese City
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... 2016 , ... For over twenty-four years, Doctors on Liens has published a directory ... high quality medical care. When the company started in 1997, the directory was a ... day and the now ten-page directory features a vast array of medical specialists ...
(Date:12/2/2016)... ... , ... Advanced Inc., a leading provider of travel therapy and travel nursing ... as Advanced Inc.’s Chief Financial Officer, effective December 1, 2016. Jason previously served as ... operational leadership experience to Advanced Inc. He began his career in finance at Ernst ...
(Date:12/2/2016)... ... ... Center for Autism and Related Disorders (CARD) Portland today announced plans to ... and other developmental disabilities. The group, which is being launched with the help of ... to share stories and advice, seek help, and continue their education on how to ...
(Date:12/2/2016)... ... ... U.S. Surgeon General, Dr. Vivek Murthy, graces the cover of the print ... to practice medicine at an early age by his father, who was also a ... prescribing medicine,” he states. “It is about building relationships with people; relationships that are ...
(Date:12/2/2016)... ... 02, 2016 , ... Mediaplanet’s newest campaign, “Digestive Heath,” hits ... proof that attitude and determination can combine into the most remarkable achievements. Over ... holidays. This campaign will offer patients a new-found hope, by seizing the opportunity ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... 2016 According to a ... by Product (Instruments, Reagents, Software), Technology (Immunoassay, Clinical ... Nephrology, Infectious Diseases) - Forecast to 2021" published ... USD 60.22 Billion in 2016. This market is ... during the forecast period (2016-2021) to reach USD ...
(Date:12/2/2016)... 2, 2016  The Addiction Treatment Advisory Group ... Managed Care Pharmacy (AMCP), has released detailed findings ... the opioid addiction crisis, including through improved access ... ATAG,s newly released paper, "The Role of ... addresses many issues around gaps and barriers to ...
(Date:12/2/2016)... 2016 Boston Scientific Corporation (NYSE: ... certain manufacturing assets and capabilities of the Neovasc, Inc., ... tissue business, as well as a 15% equity stake ... cash. The Neovasc advanced biological tissue business makes elements ... Lotus™ Valve System. * Upon completion of the ...
Breaking Medicine Technology: