Navigation Links
A 24-karat gold key to unlock the immune system
Date:3/26/2012

tioning of the immune system, Dr. Peer explains. During cell death, the hydrophobic areas of the cell membrane become exposed. The immune system then realizes that damage has occurred and begins to alert neighboring cells.

The researchers discovered that the same principle held true for the chemicals added to the gold particles' surface. The more "water-hating" the particle is, the more actively the immune system will mobilize against it, he says.

Dr. Peer observes that this is only the first step in a long line of experiments. "We are using these gold particles to tackle the question of how the immune system recognizes different particles, which might include features such as geometry, charge, curvature, and so much more. Now that we know the tool works, we can build on it," he says.

Testing the "Danger Model"

Until now, scientists have developed theories about how the immune system functions, but have lacked the machinery to test these ideas. One such theory is the "Danger Model" by Prof. Polly Matzinger, which hypothesizes that cellular damage interacts with immune cells at the membrane level. Once they identify the foreign molecule as a "danger," the immune cells send signals throughout the immune system. Their initial experiment with hydrophobicity was designed to generate a toolbox for probing this theory, says Dr. Peer, whose investigations included both in vitro and in vivo experiments using mouse immune cells.

In the future, researchers will study various bacterial, viral, or damaged cells and to make the gold nanoparticles even more similar, thereby discovering which elements of dangerous particles are calling the body's immune system to arms. "We now have the capability of using nanomaterials to probe the immune system in a very accurate manner," says Dr. Peer, a breakthrough that could revolutionize the way we understand the immune system.


'/>"/>
Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Scientist, Dr Staninger, Unlocks the Mystery of Morgellons Disease
2. What if all software was open source? A code to unlock the desktop
3. Genetics of childrens brain tumor unlocked
4. Trikz Streetball Basketball iTunes App Promotion: Only $.99 to Unlock All Content for the iPhone, iPod Touch, and iPad
5. Unlocking the Immune System's Response to Infection and Injury
6. As Science Unlocks Secrets, Cancer Rates Fall
7. Unlocking the secret of beauty: Scientists discover the complexities of attractive female bodies
8. UNC researchers inch closer to unlocking potential of synthetic blood
9. Victor Chang scientists unlock the gates on sudden cardiac death
10. Sandia Labs unlocks secrets of plague with stunning new imaging techniques
11. Scientists unlock potential of frog skin to treat cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A 24-karat gold key to unlock the immune system
(Date:8/21/2014)... 21, 2014 Living in a quality ... that comes along with it. A quality Home Owners ... such amenities are available. , Simpson ... Georgia and Community Association Management, LLC made a recent ... Company to provide an additional amenity for their neighborhood. ...
(Date:8/21/2014)... in the coronary arteries of chronic kidney disease patients ... according to a new study in the Journal ... ). Researchers at the Johns Hopkins Bloomberg School of ... commonly used measures of subclinical atherosclerosis in predicting the ... , Approximately 50 percent of all patients with chronic ...
(Date:8/21/2014)... August 21, 2014 Improv performers from ... residents with dementia at Silverado Turtle Creek memory care ... consists of entertainers ranging from ages 10 to 16, ... perform their 40-minute set. The troupe's philosophy is that ... and allows them to touch audiences regardless of their ...
(Date:8/21/2014)... August 21, 2014 The City of ... for entertainment and programming for its inaugural “Re:Imagine Garden ... October 12, 2014, from 11 a.m. to 4 p.m., ... all cars and the downtown will be filled with ... by Community Arts Resources (CARS), for all to enjoy. ...
(Date:8/21/2014)... Among seniors, dimming vision may be tied to poorer ... 2,500 people, aged 65 to 84, who were assessed when ... eight years later. Vision loss over time was associated ... the study period, the researchers reported. Although the study ... of Purdue University in West Lafayette, Ind., offered up some ...
Breaking Medicine News(10 mins):Health News:Recreation is the Heart of the Community at Simpson Mill Plantation; Chooses American Parks Company™ for New Playground Equipment 2Health News:Recreation is the Heart of the Community at Simpson Mill Plantation; Chooses American Parks Company™ for New Playground Equipment 3Health News:Measuring calcium buildup to predict heart disease in those with chronic kidney disease 2Health News:Unicorn Clearance Improv Troupe Brings Laughter to Residents with Dementia at Silverado Memory Care 2Health News:"Re:Imagine Garden Grove - A Downtown Open Streets Event" 2Health News:"Re:Imagine Garden Grove - A Downtown Open Streets Event" 3Health News:"Re:Imagine Garden Grove - A Downtown Open Streets Event" 4Health News:Failing Vision Tied to Shorter Lifespans for Seniors 2
... -- Domain Registration Corp.,(OTC Bulletin Board: DOMR), today ... all of the outstanding capital stock of China ... Islands corporation, and the,Board of Directors has adopted ... Asia, Inc.", which shall become effective upon shareholder,approval ...
... by board-certified reproductive endocrinologist Richard Sherbahn, MD, at the Advanced Fertility ... index have more eggs retrieved -- but not a correspondingly higher ... ... Gurnee, Ill. (PRWeb) May 14, 2009 -- Infertility specialist Richard ...
... Inc. today announced the addition of an outpatient appointment ... capture software, fully matching the features of pMDsoft for ... practice, saves time that can be spent with patients, ... schedule on the go. Software interfaces allow pMDsoft ...
... solutions can use CPMRC,s interdisciplinary clinical content through TSG,s integrated portal ... ... 2009 -- CPM Resource Center (CPMRC) and The ... hospitals with next-generation nursing and interdisciplinary documentation that integrates with their ...
... Imaging System and Companion C7 Dragonfly(TM) Imaging Catheter ... LightLab Imaging Inc., the pioneer and leader in ... vascular and other applications, today announced the launch ... System with the C7 Dragonfly Imaging Catheter, at ...
... pegol), the only pegylated anti-TNF, offers a new ... moderately to severely active rheumatoid arthritis- Patients treated ... significant improvements in signs and symptoms, physical function ... sustained at week 24 and for up to ...
Cached Medicine News:Health News:Domain Registration Corp Successfully Completes Reverse Merger 2Health News:Domain Registration Corp Successfully Completes Reverse Merger 3Health News:Domain Registration Corp Successfully Completes Reverse Merger 4Health News:Chicago-area Infertility Specialist Richard Sherbahn, MD, Reports a Woman's Body Mass Index Affects Her Success in Infertility Treatment 2Health News:Chicago-area Infertility Specialist Richard Sherbahn, MD, Reports a Woman's Body Mass Index Affects Her Success in Infertility Treatment 3Health News:Chicago-area Infertility Specialist Richard Sherbahn, MD, Reports a Woman's Body Mass Index Affects Her Success in Infertility Treatment 4Health News:pMDsoft Adds Mobile Appointment Calendar to iPhone Charge Capture Software 2Health News:pMDsoft Adds Mobile Appointment Calendar to iPhone Charge Capture Software 3Health News:pMDsoft Adds Mobile Appointment Calendar to iPhone Charge Capture Software 4Health News:CPM Resource Center and The Shams Group Partner to Help Hospitals Integrate Evidence-Based Clinical Content Into Information Systems 2Health News:CPM Resource Center and The Shams Group Partner to Help Hospitals Integrate Evidence-Based Clinical Content Into Information Systems 3Health News:CPM Resource Center and The Shams Group Partner to Help Hospitals Integrate Evidence-Based Clinical Content Into Information Systems 4Health News:LightLab Imaging Introduces World's Highest Resolution OCT System for Intracoronary Imaging at EuroPCR 2009 2Health News:UCB's CIMZIA(R) (certolizumab pegol) Approved by the U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis 2Health News:UCB's CIMZIA(R) (certolizumab pegol) Approved by the U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis 3Health News:UCB's CIMZIA(R) (certolizumab pegol) Approved by the U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis 4Health News:UCB's CIMZIA(R) (certolizumab pegol) Approved by the U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis 5Health News:UCB's CIMZIA(R) (certolizumab pegol) Approved by the U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis 6Health News:UCB's CIMZIA(R) (certolizumab pegol) Approved by the U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis 7Health News:UCB's CIMZIA(R) (certolizumab pegol) Approved by the U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis 8Health News:UCB's CIMZIA(R) (certolizumab pegol) Approved by the U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis 9Health News:UCB's CIMZIA(R) (certolizumab pegol) Approved by the U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis 10
(Date:8/21/2014)... Germany , Aug. 21, 2014  IBM (NYSE: ... Elektronen-Synchrotron ( DESY ), a leading national research center ... management and storage of massive volumes of x-ray data. ... based on IBM software defined technology can handle more ... performance and help scientists worldwide gain faster insights into ...
(Date:8/21/2014)... , Aug. 21, 2014  ACI Clinical ... for independent Data Monitoring Committees. Using ... 30 percent over industry standard costs and receive ... industry leader in committee services. Leveraging ... recruitment and contracting, charter development, statistical programming and ...
(Date:8/21/2014)... -- CVS Caremark Corporation (NYSE: CVS ) announced ... payable in connection with its previously announced cash tender offers ... any and all of its 6.250% Senior Notes due 2027 ... maximum amount of its 6.125% Senior Notes due 2039, 5.750% ... (collectively, the "Maximum Tender Offer Notes" and together with the ...
Breaking Medicine Technology:DESY and IBM Develop Big Data Architecture for Science 2DESY and IBM Develop Big Data Architecture for Science 3ACI Clinical: Innovation and Savings in Data Safety Monitoring Committees 2CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 2CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 3CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 4CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 5CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 6
Full Handle Laseredge Slit Blade Knife, 3.0 mm straight. Blade tip dimension: 14.4 mm x 3.0 mm x 3.7 mm....
Full Handle Laseredge Slit Blade Knife, 2.85 mm angled bevel up. Blade tip dimension: 14.4 mm x 2.8 mm x 3.7 mm....
Full Handle Laseredge Slit Blade Knife, 2.8 mm angled double bevel. Blade tip dimension: N/A x 2.8 mm x N/A....
Full Handle Laseredge Slit Blade Knife, 2.5 mm angled bevel up. Blade tip dimension: 14.4 mm x 2.5 mm x 3.7 mm....
Medicine Products: