Navigation Links
96-Week Safety and Efficacy Findings Presented for INTELENCE(TM) (etravirine) As Part of HIV Combination Therapy
Date:7/20/2009

ual to 10 percent) among patients in the INTELENCE arm vs. placebo arm, regardless of causality, were rash (21 percent vs. 12 percent), diarrhea (19 percent vs. 24 percent), nausea (15 percent vs. 14 percent), nasopharyngitis (14 percent vs. 12 percent), headache (12 percent vs. 14 percent), cough (11 percent vs. 9 percent) and herpes simplex (10 percent vs. 10 percent).
  • The incidence of nervous system and psychiatric AEs was comparable between the INTELENCE and placebo arms. Nineteen percent of patients in the INTELENCE arm experienced nervous system disorders and 20 percent reported psychiatric disorders, compared to 21 percent of patients in the placebo arm who experienced either AE.
  • Important Safety Information

    INTELENCE does not cure HIV infection or AIDS, and does not prevent passing HIV to others.

    Warnings & Precautions

    • Severe Skin Reactions: Severe and potentially life-threatening skin reactions, including Stevens-Johnson Syndrome, hypersensitivity reaction, and erythema multiforme, have occurred (<0.1%) in patients taking INTELENCE. Treatment with INTELENCE should be discontinued and appropriate therapy initiated if severe rash develops. In general, in clinical trials, rash was mild to moderate, occurred primarily in the second week of therapy, and was infrequent after Week 4. Rash generally resolved within 1-2 weeks on continued therapy. Discontinuation rate due to rash was 2%.
    • Fat Redistribution: Redistribution and/or accumulation of body fat have been observed in patients receiving antiretroviral (ARV) therapy. The causal relationship, mechanism, and long-term consequences of these events have not been established.
    • Immune reconstitution syndrome has been reported in patients treated with ARV therapy, including INTELENCE.

    Use in Specific Populations


    '/>"/>
    SOURCE Tibotec Therapeutics
    Copyright©2009 PR Newswire.
    All rights reserved

    Page: 1 2 3 4 5 6

    Related medicine news :

    1. Head-to-Head 96-Week Study Shows EPZICOM(R) is Comparable to Truvada(R) in Efficacy and Safety Measures in HIV Treatment-Naive Patients
    2. Amgen Announces KRAS Safety Update to U.S. Prescribing Information for Vectibix(R) (Panitumumab)
    3. Covanta Mendota Recognized for Its Exemplary Health and Safety Practices
    4. FDA Investigating Safety of Asthma Drug Xolair
    5. CIFOR Guidelines for Foodborne Disease Outbreak Response Published by National Food Safety Group
    6. American Imaging Management Debuts Patient Safety Podcasts
    7. Study Evaluating Efficacy and Safety of Two Low-dose Regimens of PREMARIN Vaginal Cream for the Treatment of Moderate to Severe Vaginal Atrophy Now Published
    8. Oakland Port Commission Seeks Resolution to Allow Local Officials Real Power to Clean Up Diesel Truck Pollution; Improve Security, Safety
    9. New Jersey Hospital Protects Patient Safety with Advanced Pharmacy Automation Solution
    10. LoJack SafetyNet and Project Lifesaver Help Rescue Clients Afflicted With Alzheimers/Dementia Who Wandered
    11. Researchers identify potential patient safety risks among methadone maintenance treatment patients
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:9/18/2014)... York and London. (PRWEB) September 18, 2014 ... of Computer Aided Engineering software, today announced its new ... will be utilizing the CD-adapco simulation tool, STAR-CCM+® in ... team just announced its participation in the 35th America’s ... the 35th edition of the America’s Cup is sustainability, ...
    (Date:9/18/2014)... parents eat more vegetables and drink less sugar, according ... Columbia. But it,s still not enough, the study goes ... when it comes to eating healthier at school , ... of socioeconomic status, may inform a child,s diet. , ... some post-secondary education were 85 per cent more likely ...
    (Date:9/18/2014)... in German . ... have won the ,International Space Station Research Competition, with ... prize, the scientists will see the International Space Station ... involves crystallizing two proteins of the hepatitis C virus ... the International Space Station is scheduled to lift off ...
    (Date:9/18/2014)... September 18, 2014 Relias Learning, the leader ... human services markets, today announced it has been named to ... private companies in America. , In the three-year period from ... up almost 2,000 spots on the Inc. 5000 list to ... , “The industries we serve continue to grow, and ...
    (Date:9/18/2014)... According to a new market report published by ... Industry Analysis, Size, Share, Growth, Trends and Forecast, 2014 - ... at USD 77607.7 million in 2013 and is expected to ... to reach an estimated value of USD 115474.9 million in ... growing at a rapid pace due to increasing prevalence of ...
    Breaking Medicine News(10 mins):Health News:Ben Ainslie Racing Using STAR-CCM+ Simulation Software to Design 35th America’s Cup Racing Boat 2Health News:Kids eat better if their parents went to college 2Health News:Hepatitis C virus proteins in space 2Health News:Relias Learning Named to Inc. 5000 List for Second Consecutive Year 2Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 2Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 3Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 4
    ... preventing medical support staff from completing orders for outpatient ... in a marked decrease in low-yield exams for patients, ... of Radiology . Many medical institutions request ... web-based radiology order entry systems. Some systems offer real-time ...
    ... and acceptance Three new reports describe biomarkers ... excellent and stable allograft function in the absence of ... transplants. Peter Heeger and Bernd Schrppel, at Mount Sinai ... commentary, the importance of these studies and how they ...
    ... ... its brain muscle by taking the top medal in SharpBrains first annual Brain Fitness ... ... its brain muscle by taking the top medal in SharpBrains first annual Brain Fitness ...
    ... predisposition to delivering early, , MONDAY, May 24 (HealthDay News) ... to give birth to a baby who isn,t full-term, a ... who weren,t born early but had one or more siblings ... researchers. , "There was a suspicion that preterm birth might ...
    ... To prevent rejection of their new kidneys, kidney transplant recipients ... lives. A handful of people, out of the thousands who ... drugs without losing their kidneys. Researchers studying these rare ... their white blood cells, which may one day be used ...
    ... kids with blood sugar disease , MONDAY, May 24 (HealthDay ... enteroviruses -- which can cause viral meningitis -- and diagnoses ... how the two might be linked, but the findings suggest ... for diabetes in its early stages, lead researcher Antonio Toniolo, ...
    Cached Medicine News:Health News:Simple change results in fewer unnecessary imaging exams for patients 2Health News:JCI table of contents: May 24, 2010 2Health News:JCI table of contents: May 24, 2010 3Health News:JCI table of contents: May 24, 2010 4Health News:JCI table of contents: May 24, 2010 5Health News:JCI table of contents: May 24, 2010 6Health News:JCI table of contents: May 24, 2010 7Health News:JCI table of contents: May 24, 2010 8Health News:JCI table of contents: May 24, 2010 9Health News:USA Hockey Takes Gold at Brain Fitness Innovation Awards; Allstate & Nationwide Mutual Insurance Runners-up 2Health News:USA Hockey Takes Gold at Brain Fitness Innovation Awards; Allstate & Nationwide Mutual Insurance Runners-up 3Health News:USA Hockey Takes Gold at Brain Fitness Innovation Awards; Allstate & Nationwide Mutual Insurance Runners-up 4Health News:Women Born Early More Apt to Have Preterm Baby 2Health News:Gene pattern may identify kidney transplant recipients who don't need lifelong anti-rejection drugs 2Health News:Gene pattern may identify kidney transplant recipients who don't need lifelong anti-rejection drugs 3Health News:Viral Infection Could Be Marker for Type 1 Diabetes 2
    (Date:9/18/2014)... ARBOR, Mich. , Sept. 18, 2014  A ... Research will allow the University of Michigan to establish ... The Glenn Center for Aging Research at ... evidence that drugs can slow the effects of aging ... unlock mechanisms of aging that can help develop medications ...
    (Date:9/18/2014)... SAN DIEGO , Sept. 18, 2014 /PRNewswire/ ... today announced that the U.S. Food and Drug ... patient enrollment and dosing of PEGPH20 in SWOG,s ... is designed to evaluate Halozyme,s investigational drug PEGPH20 ... FOLFIRINOX chemotherapy (mFOLFIRINOX) in patients with metastatic pancreatic ...
    (Date:9/18/2014)... -- Australian biomarker discovery company Minomic International Ltd will ... prostate cancer screening test, planning to achieve US Food ... Minomic,s proprietary MiStat™ technology is a screening assay ... known as the MIL-38 antigen. This biomarker is present ... Researchers at 11 leading urology centres in ...
    Breaking Medicine Technology:$3 M grant funds Paul F. Glenn Center for Aging Research at the University of Michigan 2$3 M grant funds Paul F. Glenn Center for Aging Research at the University of Michigan 3SWOG To Resume Clinical Trial Of Halozyme's PEGPH20 In Combination With Modified FOLFIRINOX For Advanced Pancreatic Cancer 2SWOG To Resume Clinical Trial Of Halozyme's PEGPH20 In Combination With Modified FOLFIRINOX For Advanced Pancreatic Cancer 3SWOG To Resume Clinical Trial Of Halozyme's PEGPH20 In Combination With Modified FOLFIRINOX For Advanced Pancreatic Cancer 4Minomic Launches US Pilot Study of MiStat(TM) Novel Prostate Cancer Screening Technology 2
    ... , ALLEGAN, Mich. , Jan. 19 ... release financial results for its second quarter fiscal 2010 on Tuesday, ... Company will conduct a conference call at 10:00 a.m. (ET) ... Officer. , The conference call will be available live via webcast to ...
    ... LAKE CITY , Jan. 19 World Heart ... circulatory systems, announced today that the first U.S. implant of ... INTEGRIS Baptist Medical Center ("INTEGRIS") in Oklahoma City ... the first implant in the Levacor VAD bridge-to-transplant ("BTT") study, ...
    Cached Medicine Technology:Perrigo Company Will Release Second Quarter Fiscal 2010 Results on February 2, 2010 2WorldHeart Announces First U.S. Implant of Levacor(TM) VAD Implant at INTEGRIS in Oklahoma City 2WorldHeart Announces First U.S. Implant of Levacor(TM) VAD Implant at INTEGRIS in Oklahoma City 3
    Trilogy Pacemakers incorporates the clinically proven Omniscence™ accelerometer sensor with it's automatic alogorithms. The Trilogy family of pacemakers feature an array of products for bradyar...
    The Regency family of pacemakers offers advanced, easy-to-use rate-responsive and nonrate-responsive devices....
    ... ADx pacemaker family, which ... dual-chamber pacemaker, provides clinicians ... including the revolutionary AF ... U.S. commercially approved algorithm ...
    ... ADx pacemaker family, which includes ... provides clinicians with the most ... the revolutionary AF Suppression™ algorithm, ... commercially approved algorithm designed to ...
    Medicine Products: