Navigation Links
96-Week Safety and Efficacy Findings Presented for INTELENCE(TM) (etravirine) As Part of HIV Combination Therapy
Date:7/20/2009

BRIDGEWATER, N.J., July 20 /PRNewswire/ -- Ninety-six week pooled results from two Phase 3 studies (DUET-1 and DUET-2) showed that significantly more treatment-experienced HIV-1-infected adults with non-nucleoside reverse transcriptase inhibitor (NNRTI) and protease inhibitor (PI) resistance had an undetectable viral load (<50 HIV-1 RNA copies/mL) while taking INTELENCE(TM) (etravirine) tablets plus background regimen (BR) compared with placebo plus BR. These findings were presented today at the 5(th) International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2009) in Cape Town, South Africa.

In the pooled analysis of the DUET studies at 96 weeks, 57 percent of patients in the INTELENCE arm had an undetectable viral load (<50 copies/mL) compared to 36 percent of patients in the placebo arm (p<0.0001).

"These data are important because they add to the body of knowledge on INTELENCE, an important option for treatment-experienced patients with NNRTI and PI resistance," said DUET clinical investigator Tony Mills, MD, HIV specialist in private practice, Los Angeles, and Assistant Professor of Clinical Medicine, UCLA.

When it received accelerated approval by the U.S. Food and Drug Administration (FDA) in January 2008, INTELENCE was the first NNRTI to be introduced in nearly ten years. Since then, INTELENCE has been approved in nearly 50 countries. In January 2009, an application was submitted to the FDA for traditional approval, which included 48-week data from DUET-1 and DUET-2. The FDA will need to determine if these data are sufficient to support traditional approval.

When it received accelerated approval by the U.S. Food and Drug Administration (FDA) in January 2008, INTELENCE was the first NNRTI to be introduced in nearly ten years. Since then, INTELENCE has been approved in nearly 50 countries. In Januar
'/>"/>

SOURCE Tibotec Therapeutics
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine news :

1. Head-to-Head 96-Week Study Shows EPZICOM(R) is Comparable to Truvada(R) in Efficacy and Safety Measures in HIV Treatment-Naive Patients
2. Amgen Announces KRAS Safety Update to U.S. Prescribing Information for Vectibix(R) (Panitumumab)
3. Covanta Mendota Recognized for Its Exemplary Health and Safety Practices
4. FDA Investigating Safety of Asthma Drug Xolair
5. CIFOR Guidelines for Foodborne Disease Outbreak Response Published by National Food Safety Group
6. American Imaging Management Debuts Patient Safety Podcasts
7. Study Evaluating Efficacy and Safety of Two Low-dose Regimens of PREMARIN Vaginal Cream for the Treatment of Moderate to Severe Vaginal Atrophy Now Published
8. Oakland Port Commission Seeks Resolution to Allow Local Officials Real Power to Clean Up Diesel Truck Pollution; Improve Security, Safety
9. New Jersey Hospital Protects Patient Safety with Advanced Pharmacy Automation Solution
10. LoJack SafetyNet and Project Lifesaver Help Rescue Clients Afflicted With Alzheimers/Dementia Who Wandered
11. Researchers identify potential patient safety risks among methadone maintenance treatment patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/30/2014)... Tulsa, OK (PRWEB) August 30, 2014 LiveStreamingFitness.com, ... as well as other healthy lifestyle resources, is proud to ... affordable nationwide resources for at home fitness solutions by ABC’s ... a recent featured story on ABC’s Good Morning America, “Live ... Now, you can streamline your day by streamlining your workout…to ...
(Date:8/30/2014)... AZ (PRWEB) August 30, 2014 Jake W., ... School while in the Back2Basics Outdoor Adventures transition ... to finish high school so I can actually start on ... English and math, and I'm done.” , He has six ... initial Back2Basics program. Most clients choose to continue on to ...
(Date:8/30/2014)... 30, 2014 McLeod's Sunset Park Auto ... repair shop with strong ties to the community celebrates sixty ... to announce they have been chosen by The Tampa ... auto repair. , Tim McLeod’s father, Norris (most know ... years ago. Although his son, Tim runs the day to ...
(Date:8/30/2014)... Final Cut Pro X plugin ... plugin from Pixel Film Studios. , “The TrasGhost plugin ... to tell their scary story in a suspenseful way.” ... will make their audience scream with this bone chilling ... users can awaken evil spirits with over 40 action ...
(Date:8/30/2014)... 2014 Zensah®, the leader in compression technology ... Sleeve . The camo sleeves are the first released as ... The camo line includes classic colors like army green and ... Known as tibial stress syndrome, shin splints cause dull aches ... Swollen and irritated muscles, stress fractures, or over pronation may ...
Breaking Medicine News(10 mins):Health News:LiveStreamingFitness.com is New Trend In Fitness 2Health News:McLeod's Sunset Park Auto Service Celebrates 60 Years Honored with Best of South Tampa 2Health News:Pixel Film Studios Released TransGhost Plugin for Final Cut Pro X Today 2Health News:Pixel Film Studios Released TransGhost Plugin for Final Cut Pro X Today 3Health News:Camo Compression Leg Sleeves Provide Shin Splint Relief for Runners 2
... A new article suggests that the United States ... in Cuba into a biomedical research institute dedicated ... in the open-access journal PLoS Neglected Tropical Diseases, ... would be in an optimal position to directly ...
... Sen. Clinton Defends Healthcare Plan Built on Extending Customers ... Revenue of Private ... Michael Moore,participated in a press conference call today organized ... patients from the movie SiCKO, including Reggie Cervantes, a,9/11 ...
... Ky., Feb. 26 Ventas, Inc. (NYSE:,VTR) ("Ventas" or ... Executive Officer, Debra A. Cafaro, and Executive Vice,President and ... regarding the Company at the Citi 2008 Global Property ... 2008 at 1:15 p.m.,Eastern Time., Those wishing to ...
... YORK and DALLAS, Feb. 26 HealthpointCapital, LLC.,("HealthpointCapital") ... H.,Hochschuler as Clinical Advisor to the Firm. HealthpointCapital ... focused on,orthopedic and dental device companies. Dr. Hochschuler ... of Texas Back Institute Holdings and,Chairman of the ...
... connects, educates and entertains sports world, KANSAS ... a new,online hotspot with Kansas City roots. A ... produce AthletixNation.com, the premier,community for all athletes, fans, ... AthletixNation.com is to have a positive impact,on the ...
... Feb. 26 Local communities,can be effective in ... diabetes and heart disease if they use healthy ... strategic principles identified by,leading national programs., Communities ... the nation. There are eight leading national programs ...
Cached Medicine News:Health News:From detainee facility to health advocacy center: A new role for Guantanamo? 2Health News:Michael Moore Defends 9/11 Rescue Workers and Criticizes Insurance Industry on California Nurses Association Press Call 2Health News:HealthpointCapital, LLC Appoints Stephen H. Hochschuler, M.D. as Clinical Advisor 2Health News:AthletixNation.com Launches Sports Website and Community Programs 2Health News:Effective Healthy Eating and Physical Activity Initiatives Can Reduce Health Disparities 2
(Date:8/29/2014)... , Aug. 29, 2014 Research and Markets ... Drug Pipeline Insight 2014" report to their offering. ... US is one of the largest segments of pharmaceuticals industry. ... rate, while the available therapies were unable to meet the ... the market for CNS disorder, especially over the past two ...
(Date:8/29/2014)... -- Does your doctor know what you,re smoking?  Chances are, ... to the over 112,000 currently registered patients under ... other roughly 20,300+ active physicians listed with the Colorado Dept ... even though a poll in February 2014 showed 51% of ... it. "With marijuana legalization underway, every doctor ...
(Date:8/29/2014)... SILVER SPRING, Md. , Aug. 29, 2014 /PRNewswire/ ... today that the U.S. District Court for the District ... in its favor in the company,s case against Sandoz, ... opinion, Judge Peter Sheridan ruled that U.S. ... Sandoz, Inc., and enjoined Sandoz from marketing its generic ...
Breaking Medicine Technology:US CNS Disorders Drug Pipeline Insight 2014 2Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 2Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 3Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 4District Court Decision Received In Remodulin Patent Case 2
This compact, easy-to-operate analyzer delivers basic blood gas, ISEs with direct measured total hemoglobin and saturated oxygen. Use it as a cost effective backup for the central lab or for remote p...
... performance and rapid, small volume sample ... rotor. DiscoveryTMM120 SE processes sample sizes ... with a small floor footprint, brushless ... imbalance detection, thermo-electric cooling, and automatic ...
... Efficiency, versatility, and environmental ... the Optima LE-80 K Ultracentrifuge ... Coulters innovative Optima centrifugation technology, ... to cost effectively provide advanced ...
... small-volume samples. With the ability to provide ... (fat particles in lipemic samples), the Airfuge ... Lipemic samples can be cleaned in 10 ... The easy-to-operate tabletop centrifuge: Reaches top speed ...
Medicine Products: