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9-country study shows wide variations in how women with early breast cancer are treated
Date:4/12/2010

more likely to receive a mastectomy than BCS, but this varied widely between countries, from 42% in France to 69% in the USA.

  • The overall mastectomy rate for all tumours was 44%, with the lowest rate in France (19%) and the highest rate in Greece (56%).

  • BCS was highest in women aged between 50 and 70 and mastectomy rates were highest in women under 50.

  • Despite international guidelines that radiotherapy should be part of breast-conserving therapy, France and Belgium were the only countries to report 100% treatment rates. The highest non-treatment rates were in Japan (where 14% of patients did not receive radiotherapy), the UK and Ireland (13%) and the USA (14%).

  • 39% of women received radiotherapy after a mastectomy and 93% of women received radiotherapy after BCS treatment.

  • Some 82% of patients underwent Axillary Lymph Node Dissection, ranging from 75% in the USA to 99% in the UK and Ireland.

    "Our study showed that despite international consensus guidelines, there are wide global variations in the way postmenopausal women are treated for early breast cancer" concludes Professor van de Velde.

    "We believe that there should be further efforts to ensure that women can all benefit from the most effective breast cancer treatment available, regardless of which country they live in."

    The TEAM (Tamoxifen and Exemestane Adjuvant Multinational) trial covered nine countries: Belgium (414 women), France (1,230), Germany (1,471), Greece (207), Japan (184), The Netherlands (2,753), UK and Ireland (1,275) and USA (2,232).


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  • Contact: Annette Whibley
    wizard.media@virgin.net
    Wiley-Blackwell
    Source:Eurekalert

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