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9/11 linked to 3 heart disease culprits: Obstructive sleep apnea and PTSD
Date:3/20/2014

he pathogenesis of obstructive sleep apnea," says Dr. McLaughlin. "There is strong evidence in our study data showing a significant risk of inhaled particulate matter exposure and risk of obstructed sleep apnea in the studied group of WTC first responders."

In addition, researchers linked particulate matter inhalation to the high risk of PTSD. Study results show those with very high or high exposure were more likely to have PTSD. Also, they found that those responders with PTSD also had elevated biomarkers for increased cardiovascular disease risk including high sensitivity C-reactive protein (hsCRP), a key biomarker of inflammation indicative of increased cardiovascular risk. Those WTC responders with PTSD had significantly higher hsCRP levels.

"High levels of exposure to particulate matter may lead to sleep apnea and PTSD, and as a result a high risk factor for cardiovascular disease," says Dr. McLaughlin. "As a result of our new study findings, we plan to further closely monitor our WTC first responders for heart disease warning signs."

This research study was funded by the Centers for Disease Control and Prevention (CDC) and the National Institute of Occupational Safety and Health (NIOSH).

Dr. McLaughlin is the principal investigator for the WTC-CHEST Program at Mount Sinai evaluating the effects of exposure in WTC responders 10-14 years following the events of 9/11. The research studies seek to further examine the relationship between pulmonary and cardiac function abnormalities, other markers of chronic cardiopulmonary disease, kidney dysfunction, and further elucidate the pathophysiologic effects of exposure to inhaled particulate matter on 9/11.

The WTC Health Program, Clinical Center of Excellence at Mount Sinai is a treatment and monitoring program for emergency responders, recovery workers, residents, and area workers who were affected by the terrorist attacks in New York City on September 11, 2001. The pro
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Contact: Lauren Woods
lauren.woods@mountsinai.org
646-634-0869
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert  

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