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50 years of hairy-cell leukemia research to be observed
Date:12/5/2008

. Kreitman, clinical immunotherapy section, National Institutes of Health in Bethesda, Maryland; Francesco Lauria, division of hematology and transplantation medicine immunological services, University of Siena in Siena, Italy; Dr. Alan Saven, division of hematology and oncology, Scripps Clinic, and Ida M. and Cecil Green Cancer Center, La Jolla, Calif.; Dr. Deborah Thomas, department of leukemia, University of Texas M.D. Anderson Cancer Center in Houston; and Dr. Pier Luigi Zinzani, University of Bologna in Bologna, Italy.

Hairy-cell leukemia is rare, accounting for only about 500 new cases each year, or about 2 percent of all leukemias. As a result, hematologists may encounter this disease only a few times in their career.

Symposium attendees will learn to:

  • Identify the clinical presentation and complications associated with hairy-cell leukemia.
  • Recognize the correct diagnosis and distinguish this disease from numerous lymphoid malignancies.
  • Indicate the correct time to initiate systemic therapy and select the appropriate regimen.
  • Outline the management of care when patients relapse or fail to respond to therapy, and utilize supportive care to prevent and manage infection in the patient with hairy-cell leukemia.

"We still need to do more research," says Grever. "This is like taking the football down to the 5-yard line and not getting the touchdown."

Grever will discuss long-term follow-up studies of patients who were treated for hairy-cell leukemia, including studies he conducted with Bouroncle and Dr. Eric Kraut at Ohio State's Medical Center. Bouroncle spent her entire career at Ohio State, and is now a faculty emeritus in the department of internal medicine.

Hairy-cell leukemia is seven times more common among elderly men than elderly women. Patients with this disease often have low platelet counts and blood counts, anemia and are at high risk for developing infections, Grever said. Symptoms may
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Contact: Eileen Scahill
Eileen.Scahill@osumc.edu
614-390-9832
Ohio State University Medical Center
Source:Eurekalert

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