Navigation Links
46 gene sequencing test for cancer patients on the NHS
Date:3/25/2013

change in the way we do things. This new 46 gene test moves us away from conventional methods for sequencing of single genes, and marks a huge step towards more comprehensive genome sequencing in both infrastructure and in handling the data produced.'

Dr Anna Schuh, who heads the BRC Molecular Diagnostics Centre and is a consultant haematologist at Oxford University Hospitals, adds: 'Patients like the idea of a test that can predict and say up front whether they will respond to an otherwise toxic treatment. What the patient sees is no different from present. A biopsy is taken from the patient's tumour for genetic testing with a consultant talking through the results a few days later. It is part of the normal diagnostic process.'

Cancer is often described as a genetic disease, since the transition a cell goes through in becoming cancerous tends to be driven by changes to the cell's DNA. And increasingly, new cancer drugs depend on knowing whether a mutation in a single gene is present in a patient's cancer cells.

For example, a lung cancer patient may have a biopsy taken to check for changes in the EGFR gene. If there is a mutation, the patient may then be treated with a drug that works as an EGFR inhibitor. If there is no mutation, such drugs won't work and the patient would get a different drug that would be more effective for them. Knowing the presence or absence of mutations in a certain gene can choose the treatment path for that patient.

The NHS can currently test for mutations in 2 or 3 genes genes called BRAF, EGFR or KRAS using older sequencing technology that has been around for decades. Efforts are being made to look at increasing the number of cancer genes sequenced to nine as standard.

The Oxford scientists are the first to make such multi-gene tests possible in the NHS using the latest DNA sequencing techniques. The NHS service they have launched looks for mutations in 46 genes, and they are now working
'/>"/>

Contact: Press Office
press.office@admin.ox.ac.uk
44-018-652-80530
University of Oxford
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. Eurofins MWG Operon launches SmartSeq -- An innovative DNA sequencing solution for premixed samples
2. Human bacteria sequencing project involving CU raises $340,000 online
3. Gene sequencing project mines data once considered junk for clues about cancer
4. Genomic sequencing identifies mutant drivers of common brain tumor
5. High-throughput sequencing shows potentially hundreds of gene mutations related to autism
6. Johns Hopkins scientists pair blood test and gene sequencing to detect cancer
7. Surprising findings from NHLBI Exome Sequencing Project reported
8. NIH uses genome sequencing to help quell bacterial outbreak in Clinical Center
9. New Stanford method enables sequencing of fetal genomes using only maternal blood sample
10. Gene sequencing project identifies potential drug targets in common childhood brain tumor
11. Voices Against Brain Cancer Comments on Link Between Cell Phone Use and Brain Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... ... 02, 2015 , ... Maddock Douglas is an internationally recognized ... To help manage the increasing demand for innovation as a primary growth strategy, ... Strategic Engagements. , Benkendorf is a seasoned management executive with more than 25 ...
(Date:7/1/2015)... ... 01, 2015 , ... Sir Fazle Hasan Abed, BRAC’s founder and chairperson, was ... has been recognised for his outstanding contribution to enhancing the world's production and distribution ... the World Food Prize Foundation, announced this year’s winner at a ceremony at the ...
(Date:7/1/2015)... ... July 01, 2015 , ... ... term care, specialty, combo, and compounding pharmacy operations, announces the most recent positioning ... Cardinal Health RBC event at the Venetian Las Vegas, Nevada. ...
(Date:7/1/2015)... ... July 01, 2015 , ... The Collaborative for Children and Families (CCF) ... The grant will allow CCF to improve quality of care and save costs for ... to respond to many changes in New York’s Medicaid system. Experts agree that children ...
(Date:7/1/2015)... , ... July 01, 2015 , ... Did you know ... is Men’s Health Month, and we at Advanced Fertility Center of Texas (AFCT) would ... men. , While infertility is often considered to be a “woman’s issue,” male ...
Breaking Medicine News(10 mins):Health News:Business Builder Mark Benkendorf Joins Innovation Firm Maddock Douglas 2Health News:Sir Fazle Hasan Abed Receives World Food Prize 2Health News:Sir Fazle Hasan Abed Receives World Food Prize 3Health News:Pharmacy Software Vendor, SuiteRx IPS, Officially Introducing Newly Appointed CEO at Cardinal Health Event in Las Vegas, Nevada 2Health News:Pharmacy Software Vendor, SuiteRx IPS, Officially Introducing Newly Appointed CEO at Cardinal Health Event in Las Vegas, Nevada 3Health News:Pharmacy Software Vendor, SuiteRx IPS, Officially Introducing Newly Appointed CEO at Cardinal Health Event in Las Vegas, Nevada 4Health News:The Collaborative for Children and Families Receives a Grant From The New York Community Trust to Build Capacity for Comprehensive Child Welfare 2Health News:The Collaborative for Children and Families Receives a Grant From The New York Community Trust to Build Capacity for Comprehensive Child Welfare 3Health News:Male Fertility: Improve Testosterone and Fertility With Natural Approaches 2Health News:Male Fertility: Improve Testosterone and Fertility With Natural Approaches 3Health News:Male Fertility: Improve Testosterone and Fertility With Natural Approaches 4
... more than just faithful companionship: A new study led by ... walked their dogs were 34 percent more likely to meet ... Mathew Reeves, show that promoting dog ownership and dog walking ... meet recommended levels of leisure-time physical activity become healthier. ...
... In an effort to improve treatment and one ... Foundation today joined with key donors and community leaders ... of globalCure is an alliance between TGen and the ... cancer scientists, physicians and researchers, armed with the most ...
... , WEDNESDAY, March 9 (HealthDay News) -- The U.S. ... new treatment option in more than 50 years when it approved ... debilitating autoimmune disorder. Injected directly into a vein, Benlysta is ... the number of abnormal B cells believed to be at the ...
... Two studies published by an interdisciplinary team of Hong ... Cell Transplantation (20:1), now freely available on-line at ... adult brain cells (neurogenesis) in two critical areas of ... a stress reducer and also to sexual behavior and ...
... , THURSDAY, March 10 (HealthDay News) -- ... bones that surgeons should adjust for when they perform ... researchers. Previous studies have found that cerebral palsy ... the hips, but this is the first study to ...
... By Randy Dotinga HealthDay Reporter , WEDNESDAY, March ... diabetes were able to get injections of a new insulin drug ... findings still need to be confirmed in another phase of research, ... it were approved for this use. But those caveats aside, ...
Cached Medicine News:Health News:Grab the leash: Dog walkers more likely to reach exercise benchmarks 2Health News:TGen Foundation launches 'globalCure,' targets pancreatic cancer 2Health News:FDA Approves 1st New Lupus Drug in More Than 50 Years 2Health News:Brain cell regrowth linked to benefits of exercise, sexual behaviors and reproductive issues 2Health News:Brain cell regrowth linked to benefits of exercise, sexual behaviors and reproductive issues 3Health News:New Drug May Trim Insulin Injections to Just 3 a Week 2
(Date:7/1/2015)... and FT LAUDERDALE, Florida , ... ("OrbusNeich"), a designer, developer, manufacturer and marketer of innovative medical ... on May 13, 2015, it prevailed in a final opposition ... Patent EP 1 341 482 - STENT HAVING HELICAL ELEMENTS ... review in the EPO and has been upheld as a ...
(Date:7/1/2015)... SAN DIEGO , July 1, 2015  MEI Pharma, ... the clinical development of novel therapies for cancer, announced today ... Executive Officer, will present at the inaugural Cantor Fitzgerald Healthcare ... time from Le Parker Meridien in ... can be accessed at www.meipharma.com . A replay will ...
(Date:7/1/2015)... Lupin , ... Number of MPP Sub-licensees to Fourteen Companies   ... the rapid expansion of its network of generic manufacturers to ... develop MPP-licensed antiretrovirals (ARVs). New companies Lupin and Strides Arcolab ... HIV medicine the MPP licensed from ViiV Healthcare two months ...
Breaking Medicine Technology:OrbusNeich Announces Favorable Ruling from the European Patent Office and Initiation of Litigation Against Terumo Corporation 2MEI Pharma to Present at Cantor Fitzgerald Healthcare Conference 2The Medicines Patent Pool Increases its Generic Manufacturing Network to Ramp-Up Production of Low Cost Antiretrovirals (ARVs) 2The Medicines Patent Pool Increases its Generic Manufacturing Network to Ramp-Up Production of Low Cost Antiretrovirals (ARVs) 3
The seed alignment tray aligns seeds and spacers for easy access to be picked up by the SeedVac™. It also interfaces with the seed sterilization and sorting tray for protection from radiation....
MT-BT-5011-25 Prostate seeding needle (set of 25 unloaded needles).,MT-BT-5011-P Prostate seeding needle, pre-plugged and pre-sterilized, unloaded or for use with MEDTECs ASAP™ pre-load seedin...
... ACMI™ offers five classes of ... vaporization, cutting loops, knife, roller bar ... are the only electrodes specifically integrated ... surgical tissue removal with minimal bleeding, ...
... Nephroscope, with a stainless steel shaft, combines ... lumbotome, for precise pre-cutting of scar tissue, ... access. The 13.5 Fr. oval working channel ... and lithotripsy probes, and allows a high ...
Medicine Products: