Navigation Links
4 possible risk factors for ovarian cancer found
Date:9/19/2010

ROCHESTER, Minn. -- A consortium of cancer researchers has identified four chromosome locations with genetic changes that are likely to alter a woman's risk of developing ovarian cancer. The findings appear in Nature Genetics in an article authored by a Mayo Clinic researcher.

Researchers say that while more needs to be learned about the function of the specific chromosomal regions involved in susceptibility, the discoveries move them a major step closer to individualized risk assessments for ovarian cancer. In the future, women at greatest risk due to these and other inherited changes may be offered increased surveillance or preventive measures.

"In searching the genome, we came up with some surprises on chromosomes 2, 3, and 17," says Ellen Goode, Ph.D., Mayo Clinic genetic epidemiologist and lead author. "While examining the usual suspects in a region on chromosome 8, we found that SNPs associated with ovarian cancer risk were located quite a distance away from those associated with risk of other cancers, which suggest that they may act through a different mechanism." SNPs, single nucleotide polymorphisms, are common genetic variants associated, in this case, with cancer risk.

The findings come from a large genome-wide association study (GWAS) that spanned three continents. Following an initial study in over 1,700 cases, the researchers followed up with a study of over 24,000 women. They narrowed the focus to nine regions and confirmed that three loci (locations on the chromosome) were much stronger than the others and a fourth "approached genome-wide significance." These particular loci are associated with serous ovarian cancer, the most aggressive and common of the four main types of the disease.


'/>"/>

Contact: Robert Nellis
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1

Related medicine news :

1. FDA Chief Says More Egg Recalls Possible
2. UC San Diego researchers find cause of metabolic disease -- and possible cure
3. Intensively lowering glucose: Possible benefits must be weighed against risks
4. International liver cancer congress provides possible solutions to reduce significant burden
5. Study shows a possible link between preschoolers cavities and excess body fat
6. Possible link between sleep-disordered breathing and cardiovascular disease revealed
7. Online Housecalls, Improved Patient Care and Increased Communication Between Doctors and Healthcare Professionals Now Made Possible Through Docgreet.com
8. Breast Cancer Vaccine Possible, Scientists Say
9. Complicated Surgeries Carry Greater Risks, Possible Need for New York Medical Malpractice Attorneys According To David Perecman
10. Some bisphosphonates users unfamiliar with drugs possible side effects on oral health
11. Novel RNA interference screening technique identifies possible path for malignant glioma treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... ... While it’s often important to take certain medications during the night, finding ... identified a solution. , She developed a prototype for MOTION LIGHT-UP PILL BOX to ... the need to turn on a light when taking medication during the night, allowing ...
(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a leading Health and Nutrition ... the Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing CBD market ... can be easily incorporated into liquid products, while reducing costs to end users. , ...
(Date:10/13/2017)... Shelton, CT (PRWEB) , ... October 13, 2017 , ... ... and long-term care services, staged a mock evacuation of the facility as part of ... Department, Shelton Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well ...
(Date:10/13/2017)... ... ... Ellevate Network, the leading network for professional women, brought together some of ... their inaugural Summit in New York City in June. The event was livestreamed with ... 3 million. To watch the Mobilize Women video, click here . , ...
(Date:10/13/2017)... ... ... Talented host, actor Rob Lowe, is introducing a segment ... of "Success Files," which is an award-winning educational program broadcasted on PBS Member ... with passion and integrity. , Sciatica occurs when the sciatic nerve in the ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... Sept. 28, 2017 Hill-Rom Holdings, Inc. (NYSE: ... conference call and webcast on Friday, November 3, 2017, ... and ending at approximately 8:30 a.m. (CDT) / 9:30 ... company,s 2017 financial performance and guidance for 2018, Hill-Rom ... to enhance operational performance, and long-range financial outlook through ...
(Date:9/25/2017)... Sept. 25, 2017  EpiVax, Inc., a leader ... and immune-engineering today announced the launch of EpiVax ... of personalized therapeutic cancer vaccines. EpiVax has provided ... access to enabling technologies to the new precision ... lead EpiVax Oncology as Chief Executive Officer. Gad ...
(Date:9/19/2017)... , Sept. 19, 2017   ZirMed Inc ., a ... today announced that it has been ranked #1 by its ... Book™ Rankings 2017 User Survey. ZirMed was recognized as ... large hospitals and medical centers over 200 beds and holds ... healthcare technology user survey history. ...
Breaking Medicine Technology: