Navigation Links
3 studies confirm the value of etanercept therapy in treating juvenile idiopathic arthritis
Date:6/12/2009

nts with refractory juvenile idiopathic arthritis. (THU0426)

In 53 JIA patients, who previously did not respond to other second-line drugs, data were collected to evaluate HRQoL during treatment with etanercept. HRQoL was measured by the Childhood Health Assessment Questionnaire (CHAQ), Child Health Questionnaire (CHQ) and Health Utilities Index mark 3 (HUI3) before start and after 3, 15 and 27 months. At the same time-points, information on JIA disease activity variables were also collected, including; physician's global assessment through the Visual Analogue Scale (VAS), number of active and limited joints and erythrocyte sedimentation rate. Linear mixed models were used to assess outcomes over time.

Significant improvements in HRQoL were seen during the 27 month study period. The disease specific CHAQ, including the VAS pain and VAS well-being scores showed a significant improvement on all domains (p<0.001). The generic health-profile measure CHQ improved on all the health concepts (p<0.05) except 'family cohesion', which is known to be unaffected by JIA.1 The generic preference-based HUI3 showed significant improvement (p<0.05) on the more specific areas of 'pain', 'ambulatory', and 'dexterity'. In accordance, disease activity variables improved significantly over time (p<0.001).

Dr Femke H.M. Prince of the Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands, said: "JIA, the most common cause of chronic arthritis in children, frequently results in physical disabilities and chronic pain influencing daily life. The results for the Arthritis and Biologicals in Children project show impressive improvement on all domains of Health-Related Quality of Life impaired by JIA during treatment with etanercept. This indicates that these previously severely ill children, as well as their families, gain great benefits from this treatment. The results of our studies add to the bank of research on the role of etanercept in treating JIA p
'/>"/>

Contact: Rory Berrie
eularpressoffice@uk.cohnwolfe.com
44-789-439-6425
European League Against Rheumatism
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Press Releases on BPA Studies By-Pass Scientific Process
2. Studies Report More Harmful Effects From BPA
3. Studies Highlight a Revolutionary New Method of Treating Post-Operative Bruising
4. ACTEMRA(R) (tocilizumab) Studies to be Featured at the European League Against Rheumatism (EULAR) Congress
5. AstraZeneca Studies Show Relief of Nighttime Heartburn and Reduction in GERD-Related Sleep Disturbances
6. Transcept Pharmaceuticals Presents Data from Studies of Two Product Candidates at Annual Meeting of the American Psychiatric Association
7. Genomic Health to Present Multiple New Studies at the American Society of Clinical Oncology Annual Meeting
8. Studies Reveal Exposure to Pesticides During Pregnancy Increases Risk of Premature Birth, Low-Birth Weight, Neurological Problems and Diabetes
9. Rexin-G Controls Tumor Growth and Improves Survival in Chemotherapy-Resistant Sarcoma and Osteosarcoma: Phase I/II and Phase II Studies, ASCO 2009
10. 2 studies examine medical consequences of police use of force during restraint
11. Two Studies at AACE 2009 Annual Meeting Highlight Effects of Welchol(R) (colesevelam HCl) on Blood Glucose and LDL-C in Patients with Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... 24, 2014 (HealthDay News) -- Adults who experienced ... of migraine headaches, suggests a study published online ... "Childhood maltreatment can have long-lasting effects, like ... adulthood," study author Dawn Buse, director of behavioral ... City, said in a journal news release. ...
(Date:12/24/2014)... HealthDay Reporter WEDNESDAY, ... likely to start smoking or drinking with each additional ... conduct disorder, new research suggests. "Our findings ... of substance use as [these] children approach adolescence," said ... Pediatric Research Group, which is part of Cincinnati Children,s ...
(Date:12/24/2014)... Steven Reinberg HealthDay Reporter ... from the American Diabetes Association (ADA) call for giving the ... to help prevent heart disease. These new standards bring ... and American Heart Association, which also recommend giving low- or ... including people with diabetes. "We agree that the decision ...
(Date:12/24/2014)... ladies, new fashionable outfits are necessary when heading into a ... Angeldress.co.uk has chosen some of their best dresses ... by launching a promotion on its cheap clothes and fashion ... off, like a cheap suit. , “All items are in ... are among the hottest items in the global market. They ...
(Date:12/24/2014)... 2014 Dr. Svetlana Gomer, MGS Tewksbury ... nation gathered with US Marines on November 14, 2014 ... for the Toys for Tots Literacy Program. This ... new books and audio books for the Toys for ... this Christmas. It represents another major strike in the ...
Breaking Medicine News(10 mins):Health News:Abuse in Childhood Tied to Migraines in Adulthood 2Health News:ADHD May Raise Teens' Odds for Smoking, Drinking 2Health News:ADHD May Raise Teens' Odds for Smoking, Drinking 3Health News:Nearly All Diabetics Should Be on Cholesterol-Lowering Drugs: Experts 2Health News:Nearly All Diabetics Should Be on Cholesterol-Lowering Drugs: Experts 3Health News:Angeldress.co.uk Starts Its Big Sales by Offering Various Kinds of Cheap Clothes and Fashion Accessories 2Health News:Dr. Svetlana Gomer, MGS Tewksbury Dental and Other Dentists Working With the U.S. Marines Strike Again In the Battle Against Illiteracy 2Health News:Dr. Svetlana Gomer, MGS Tewksbury Dental and Other Dentists Working With the U.S. Marines Strike Again In the Battle Against Illiteracy 3
... Guaranteed Healthcare, AFL-CIO Secretary Treasurer Richard Trumka to Keynote ... ... Patients, First Responders to Join Emotional September 11th Rally With ... Californians, OAKLAND, Calif., Sept. 6 The California Nurses,Association/National ...
... to Support EIF,s Women,s ... Cancer Research Fund, ... edition version of its all-new, eagerly-awaited 2008,C350 Sport Sedan to raise ... initiative developed in partnership with the Entertainment,Industry Foundation,s (EIF) Women,s Cancer ...
... will participate in a nationwide study to pinpoint the ... infection. , The objective of this trial is ... people who have MRSA, said David Karras, professor and ... Medicine and Hospital, who will lead the research efforts ...
... Tim McGraw and Friends, ... Presented by Anheuser-Busch Companies, NAPA, Calif., Sept. 6 ... on Friday, Nov. 2 at Grant,s Farm,the ancestral home of ... "Denim & Diamonds: An Evening with Tim McGraw and,Friends". Proceeds ...
... Predictive medicine company,PreMD Inc. (TSX: PMD; Amex: PME) ... U.S. Food and Drug Administration (FDA) regarding its,510(k) ... POC skin,cholesterol test. PreMD submitted the 510(k) application ... to obtain broader clearance in the assessment of,cardiovascular ...
... may open a window of vulnerability for developing binge ... according to a study from the University of North ... , In a long-term study of 100,000 pregnant Norwegian ... incidences of binge eating disorder that began during pregnancy. ...
Cached Medicine News:Health News:Hundreds of RNs from Across U.S. and World to Join California Nurses Association/NNOC National Convention 2Health News:Mercedes-Benz Special Edition C350 Sport Sedan to Raise $1 Million for Saks Fifth Avenue's KEY TO THE CURE 2Health News:Mercedes-Benz Special Edition C350 Sport Sedan to Raise $1 Million for Saks Fifth Avenue's KEY TO THE CURE 3Health News:Mercedes-Benz Special Edition C350 Sport Sedan to Raise $1 Million for Saks Fifth Avenue's KEY TO THE CURE 4Health News:Temple Emergency Medicine receives $1.8M to find best MRSA treatment 2Health News:Temple Emergency Medicine receives $1.8M to find best MRSA treatment 3Health News:The Tug McGraw Foundation Announces 2007 Fundraising Gala 2Health News:The Tug McGraw Foundation Announces 2007 Fundraising Gala 3Health News:The Tug McGraw Foundation Announces 2007 Fundraising Gala 4Health News:PreMD Provides Update on 510(k) Application for PREVU(x) POC 2Health News:Pregnancy may increase the risk of developing binge eating disorder 2
(Date:12/22/2014)... , Dec. 22, 2014 Research and Markets ... addition of the "Investment Analysis of the ... their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... the US medical device sector identifies the key ... venture capital investments, and mergers and acquisitions. ...
(Date:12/22/2014)... Cyberonics, Inc. (NASDAQ: CYBX ), a global leader ... today announced it will participate in the 33 rd ... in San Francisco . ... speak at 11:00 AM Pacific Time.  A live audio webcast ... Investor Relations link on the Cyberonics home page at ...
(Date:12/22/2014)... MARLBOROUGH, Mass , Dec. 22, 2014 /PRNewswire/ -- ... a biotechnology company focused on discovering, developing and ... using RNA-targeted technologies, today issued the following open ... Geert Cauwenbergh , Dr. Med. Sc. ... few days a number of inaccurate statements posted ...
Breaking Medicine Technology:Investment Analysis of the US Medical Device Sector 2RXi Pharmaceuticals Issues Open Letter to Shareholders 2RXi Pharmaceuticals Issues Open Letter to Shareholders 3RXi Pharmaceuticals Issues Open Letter to Shareholders 4RXi Pharmaceuticals Issues Open Letter to Shareholders 5RXi Pharmaceuticals Issues Open Letter to Shareholders 6
... March 17 Alexza,Pharmaceuticals, Inc. (Nasdaq: ALXA ) ... ended December 31, 2007, and provided an update,on the ... "During 2007 and the first quarter of 2008, we ... an important transitional year for,Alexza, as we initiate the ...
... Eye via,Ophthalmic Artery, WASHINGTON, March 17 ... -- a,deadly, inherited cancer of one or both ... having their eyes surgically removed (enucleated),according to the ... Society of,Interventional Radiology,s 33rd Annual Scientific Meeting. Advanced,retinoblastoma ...
Cached Medicine Technology:Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status 2Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status 3Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status 4Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status 5Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status 6Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status 7Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status 8Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status 9Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status 10Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status 11Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status 12Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status 13Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status 14New Localized Cancer Treatment for Advanced Retinoblastoma Saves Children From Having Eyes Removed, Restores Vision in Some Cases 2New Localized Cancer Treatment for Advanced Retinoblastoma Saves Children From Having Eyes Removed, Restores Vision in Some Cases 3New Localized Cancer Treatment for Advanced Retinoblastoma Saves Children From Having Eyes Removed, Restores Vision in Some Cases 4
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: