Navigation Links
3 studies confirm the value of etanercept therapy in treating juvenile idiopathic arthritis
Date:6/12/2009

nts with refractory juvenile idiopathic arthritis. (THU0426)

In 53 JIA patients, who previously did not respond to other second-line drugs, data were collected to evaluate HRQoL during treatment with etanercept. HRQoL was measured by the Childhood Health Assessment Questionnaire (CHAQ), Child Health Questionnaire (CHQ) and Health Utilities Index mark 3 (HUI3) before start and after 3, 15 and 27 months. At the same time-points, information on JIA disease activity variables were also collected, including; physician's global assessment through the Visual Analogue Scale (VAS), number of active and limited joints and erythrocyte sedimentation rate. Linear mixed models were used to assess outcomes over time.

Significant improvements in HRQoL were seen during the 27 month study period. The disease specific CHAQ, including the VAS pain and VAS well-being scores showed a significant improvement on all domains (p<0.001). The generic health-profile measure CHQ improved on all the health concepts (p<0.05) except 'family cohesion', which is known to be unaffected by JIA.1 The generic preference-based HUI3 showed significant improvement (p<0.05) on the more specific areas of 'pain', 'ambulatory', and 'dexterity'. In accordance, disease activity variables improved significantly over time (p<0.001).

Dr Femke H.M. Prince of the Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands, said: "JIA, the most common cause of chronic arthritis in children, frequently results in physical disabilities and chronic pain influencing daily life. The results for the Arthritis and Biologicals in Children project show impressive improvement on all domains of Health-Related Quality of Life impaired by JIA during treatment with etanercept. This indicates that these previously severely ill children, as well as their families, gain great benefits from this treatment. The results of our studies add to the bank of research on the role of etanercept in treating JIA p
'/>"/>

Contact: Rory Berrie
eularpressoffice@uk.cohnwolfe.com
44-789-439-6425
European League Against Rheumatism
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Press Releases on BPA Studies By-Pass Scientific Process
2. Studies Report More Harmful Effects From BPA
3. Studies Highlight a Revolutionary New Method of Treating Post-Operative Bruising
4. ACTEMRA(R) (tocilizumab) Studies to be Featured at the European League Against Rheumatism (EULAR) Congress
5. AstraZeneca Studies Show Relief of Nighttime Heartburn and Reduction in GERD-Related Sleep Disturbances
6. Transcept Pharmaceuticals Presents Data from Studies of Two Product Candidates at Annual Meeting of the American Psychiatric Association
7. Genomic Health to Present Multiple New Studies at the American Society of Clinical Oncology Annual Meeting
8. Studies Reveal Exposure to Pesticides During Pregnancy Increases Risk of Premature Birth, Low-Birth Weight, Neurological Problems and Diabetes
9. Rexin-G Controls Tumor Growth and Improves Survival in Chemotherapy-Resistant Sarcoma and Osteosarcoma: Phase I/II and Phase II Studies, ASCO 2009
10. 2 studies examine medical consequences of police use of force during restraint
11. Two Studies at AACE 2009 Annual Meeting Highlight Effects of Welchol(R) (colesevelam HCl) on Blood Glucose and LDL-C in Patients with Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... Sept. 15, 2014 (HealthDay News) -- U.S. heart experts ... electrocardiogram (ECG) when evaluating young people for underlying heart ... The American Heart Association and the American College of ... detailed personal and family medical history along with a ... or congenital (existing from birth) risks for sudden cardiac ...
(Date:9/15/2014)... September 12, 2014 - An estimated 8% of ... at some point during their lifetime. Brought on by ... the result of altered chemistry and physiology of the ... brain versus one altered by PTSD is essential to ... Center for BrainHealth at The University of Texas at ...
(Date:9/15/2014)... September 15, 2014 This year, ... founding in 2007. To mark the special occasion, Avenidas ... supporting the village and helping it to get started ... secure and fun community for seniors. Members of Avenidas ... and live in their own homes. They are able ...
(Date:9/15/2014)... Amy Norton HealthDay Reporter ... small number of medications are responsible for sending thousands of ... government study finds. Each year between 2007 and 2011, ... after getting a hold of family members, medication, according to ... "Three-quarters of those children were just 1 or 2 years ...
(Date:9/15/2014)... 15, 2014 Array Health ... technology, today announced that Independence Blue Cross ... southeastern Pennsylvania, has selected the Array Spectrum™ Private ... exchange marketplace for employers with more than 100 ... Spectrum™, Independence will offer employer groups a comprehensive ...
Breaking Medicine News(10 mins):Health News:Heart Docs Don't Recommend Routine ECGs for Young Athletes 2Health News:Heart Docs Don't Recommend Routine ECGs for Young Athletes 3Health News:EEG study findings reveal how fear is processed in the brain 2Health News:Avenidas Village Celebrates Anniversary 2Health News:Small Number of Drugs Behind Kids' Accidental Poisonings: CDC 2Health News:Small Number of Drugs Behind Kids' Accidental Poisonings: CDC 3Health News:Independence Blue Cross Selects Array Spectrum™ Private Health Insurance Exchange Technology 2Health News:Independence Blue Cross Selects Array Spectrum™ Private Health Insurance Exchange Technology 3
... comes to chronic disease care, study finds , , TUESDAY, ... factor driving soaring rates of chronic disease in the ... their European counterparts, a new study finds. , It,s ... such as diabetes and heart disease account for some ...
... October 1, 2007 -- According to a study conducted ... lesbian, gay, and bisexual populations, blacks and Latinos do ... on the theory that stress related to prejudice would ... black lesbians, gay men, and bisexuals face prejudice related ...
... treatments can be the worst news a cancer patient ... of Missouri-Columbia is working steadfastly to learn why some ... drug cisplatin, in hopes of identifying the particular genes ... as possible. , In a paper published in the ...
... The first significant genetic finding in premenstrual dysphoric ... a very severe form of the more commonly known ... 5-8% of women, and is associated with severe emotional ... anger, headaches, weight gain and more, to such an ...
... When an adult suffers a cardiorespiratory arrest the rapid ... avoid sudden death in many cases. Nevertheless, defibrillation also ... that passes from the moment of the attack, the ... in order to avoid avoidable deaths, more and more ...
... N.J., Oct. 2 MedQuist Inc.,(Pink Sheets: ... multi-year agreement,with MedAssets Supply Chain Systems, one ... the relationship with MedAssets and,allowing them to ... speech,recognition and clinical documentation solutions. As ...
Cached Medicine News:Health News:Obesity Driving Rising U.S. Health Costs 2Health News:Obesity Driving Rising U.S. Health Costs 3Health News:Black gay men, lesbians, have fewer mental disorders than whites, says Mailman School of PH study 2Health News:MU researchers studying model to learn why certain cancers become resistant to drugs 2Health News:First significant genetic finding in severe PMS, or PMDD 2Health News:Algorithms to reanimate the heart 2Health News:Algorithms to reanimate the heart 3Health News:MedQuist and MedAssets Sign Multi-Year Contract for Clinical Documentation Workflow Solutions 2Health News:MedQuist and MedAssets Sign Multi-Year Contract for Clinical Documentation Workflow Solutions 3
(Date:9/15/2014)... 15, 2014 /PRNewswire/ -  Pivotal Therapeutics Inc. (OTCQX:PVTTF; ... company with a focus on Omega-3 therapies for ... the Board of Directors approved the granting of ... the close of business on Friday, September 12, ... common shares of the Company were granted in ...
(Date:9/15/2014)... 15, 2014 /PRNewswire-iReach/ -- "Spain Aesthetic Lasers and ... market data on the Spain Aesthetic Lasers and ... millions of US dollars, volume (in units) and ... Invasive Body Contouring Devices (Laser-Assisted Liposuction (LAL) Devices ... Devices, Ultrasound-Assisted Liposuction (UAL) Devices and Power Assisted ...
(Date:9/15/2014)... /PRNewswire-iReach/ -- On September 8, 2014, Dr. ... a Citizen Petition to Dr. Margaret Hamburg ... another Black Box Warning to Levaquin, Cipro, and ... a Black Box Warning for the following psychiatric ... or acts, loss of consciousness, delirium, depressed level ...
Breaking Medicine Technology:Pivotal Therapeutics Grants Incentive Stock Options 2Spain Aesthetic Lasers and Energy Devices Market (LAL, RFAL, PAL, HIFU) Outlook to 2020 2Spain Aesthetic Lasers and Energy Devices Market (LAL, RFAL, PAL, HIFU) Outlook to 2020 3Spain Aesthetic Lasers and Energy Devices Market (LAL, RFAL, PAL, HIFU) Outlook to 2020 4Spain Aesthetic Lasers and Energy Devices Market (LAL, RFAL, PAL, HIFU) Outlook to 2020 5Quinolone Vigilance Foundation Supports Citizen Petition Requesting Another Black Box Warning for Levaquin, Cipro, Avelox 2Quinolone Vigilance Foundation Supports Citizen Petition Requesting Another Black Box Warning for Levaquin, Cipro, Avelox 3
... Reportlinker.com announces that a new ... its catalogue: Epidemiology: ... risk factor for deep vein thrombosis ... http://www.reportlinker.com/p0536561/Epidemiology-Major-Abdominal-Surgery-–-A-key-risk-factor-for-deep-vein-thrombosis-and-pulmonary-embolism.html?utm_source=prnewswire&utm_medium=pr&utm_campaign=NoCategory ...
... 2011 Zimmer Holdings, Inc. (NYSE and SIX: ZMH), ... will be participating in the Goldman Sachs 32nd Annual ... Palos Verdes, California, on June 7, 2011, at 8:40 ... of the presentation can be accessed via Zimmer,s Investor ...
Cached Medicine Technology:Reportlinker Adds Epidemiology: Major Abdominal Surgery - A key risk factor for deep vein thrombosis and pulmonary embolism 2Zimmer Holdings to Present at the Goldman Sachs 32nd Annual Global Healthcare Conference 2
Acuvue Toric is an exceptionally comfortable soft contact lens made especially for people with astigmatism. The Acuvue Toric lens is designed to comfortably fit the unique shape of your eye....
C 2.3K with lightweight headband: the practical alternative for spectacle-wearers. Delivered in protective designer case....
Easyloupes are exceptional optics that you have come to expect from Oculus. Available in either 1.8x or 2.5x magnification and 40 cm working distance (15.75 inches), they have the well-known durabili...
... designed for computer operators who require ... placed at different heights and distanced ... Card is printed two sided- black ... and uses two type sizes to ...
Medicine Products: