Navigation Links
3 studies confirm the value of etanercept therapy in treating juvenile idiopathic arthritis
Date:6/12/2009

otal of 179 JIA patients; average age of 5.8 years) who continued with the treatment eventually responded. The researchers in this study thereby suggest extending the use of etanercept in non-responding patients beyond the commonly recommended three-month therapy window to achieve higher response rates in JIA patients.

* The American College of Rheumatology (ACR) pediatric criteria assess patient response to a treatment. An ACR Pedi 30 response represents a >30% improvement in JIA signs and symptoms, such as the number of swollen joints with loss of motion, assessment of pain and level of disability. ACR Pedi 50 represents a >50% improvement, and ACR Pedi 70 represents a >70% improvement.

Further details on the three studies are outlined below:

1. Safety and efficacy of etanercept in a cohort of juvenile idiopathic arthritis (JIA) patients under four years of age. (OP-0137)

Thirty-three patients with unresponsive JIA under four years of age in a single centre were treated with etanercept for a mean of 23 months (range 6-86), with all receiving other concurrent drug treatments. Efficacy (using ACR Pediatric 30, 50 and 70 criteria for improvement) and safety end points were recorded at each hospital visit.

The ACR Pedi 30 response was reached by 82% (27) after 6 months and 85% (28) at the last observation. The ACR Pedi 50 response was reached by 76% (25) at 6 months and 85% (28) at the last follow-up, and the ACR Pedi 70 response was reached by 48% and 73% respectively.

Four patients (12%) developed mild adverse events: including one case of cytomegalovirus infection and three varicella zoster virus (VZV) infections. One patient experienced a serious adverse event and was hospitalised for a necrotising fasciitis during VZV infection. No cases of tuberculosis, opportunistic infections or malignancies were reported.

2. Major improvements in health-related quality of life during the use of etanercept in patie
'/>"/>

Contact: Rory Berrie
eularpressoffice@uk.cohnwolfe.com
44-789-439-6425
European League Against Rheumatism
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Press Releases on BPA Studies By-Pass Scientific Process
2. Studies Report More Harmful Effects From BPA
3. Studies Highlight a Revolutionary New Method of Treating Post-Operative Bruising
4. ACTEMRA(R) (tocilizumab) Studies to be Featured at the European League Against Rheumatism (EULAR) Congress
5. AstraZeneca Studies Show Relief of Nighttime Heartburn and Reduction in GERD-Related Sleep Disturbances
6. Transcept Pharmaceuticals Presents Data from Studies of Two Product Candidates at Annual Meeting of the American Psychiatric Association
7. Genomic Health to Present Multiple New Studies at the American Society of Clinical Oncology Annual Meeting
8. Studies Reveal Exposure to Pesticides During Pregnancy Increases Risk of Premature Birth, Low-Birth Weight, Neurological Problems and Diabetes
9. Rexin-G Controls Tumor Growth and Improves Survival in Chemotherapy-Resistant Sarcoma and Osteosarcoma: Phase I/II and Phase II Studies, ASCO 2009
10. 2 studies examine medical consequences of police use of force during restraint
11. Two Studies at AACE 2009 Annual Meeting Highlight Effects of Welchol(R) (colesevelam HCl) on Blood Glucose and LDL-C in Patients with Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2015)... , ... September 02, 2015 , ... ... Things, announces its latest addition to its screen mirroring and extending product line ... Extended Wireless Display, which operates in local WIFI setting, the new Splashtop Wired ...
(Date:9/2/2015)... ... ... Good health and a good cause paired up at The Barclays this past ... to the New Jersey Golf Foundation through its Healthy Steps Challenge. After making ... BCBSNJ challenged PGA TOUR golfer and NJ native Morgan Hoffmann to add more by ...
(Date:9/2/2015)... Laguna Beach, Calif. (PRWEB) , ... September 02, ... ... and injection therapy clinic combining both naturopathic and allopathic medicine, opens its second ... 92651. The new clinic features roughly 1000 square feet of lounge space for ...
(Date:9/2/2015)... (PRWEB) , ... September 02, 2015 , ... ... Cypress Benefit Administrators is taking action after seeing a significant increase in ... Argus Claim Review division has found many cases of OON ASCs encouraging members ...
(Date:9/2/2015)... ... September 02, 2015 , ... Amada Senior Care, premier provider of in-home care ... Johnson County location. Amada franchise partners Mike and Mell Fleming came to ... and spent over 20 years in medical device sales while Mell spent over 30 ...
Breaking Medicine News(10 mins):Health News:Splashtop Launches Wired XDisplay, the Fastest Screen Sharing Solution for Extending and Mirroring Your Computer Screen to Mobile Devices 2Health News:Splashtop Launches Wired XDisplay, the Fastest Screen Sharing Solution for Extending and Mirroring Your Computer Screen to Mobile Devices 3Health News:Horizon BCBSNJ’s Healthy Steps Challenge Raises an Additional $6,000 for the NJ Golf Foundation with Help from PGA TOUR Golfer Morgan Hoffmann 2Health News:Horizon BCBSNJ’s Healthy Steps Challenge Raises an Additional $6,000 for the NJ Golf Foundation with Help from PGA TOUR Golfer Morgan Hoffmann 3Health News:The Hydration Room Opens New Location In Laguna Beach, California 2Health News:The Hydration Room Opens New Location In Laguna Beach, California 3Health News:The Hydration Room Opens New Location In Laguna Beach, California 4Health News:TPA Cracks Down on Forbidden Tactics Used by Out-of-Network Surgical Centers 2Health News:TPA Cracks Down on Forbidden Tactics Used by Out-of-Network Surgical Centers 3Health News:Amada Senior Care Expands to Greater Kansas City 2
... Offer Broader ChoiceEAGAN, Minn., April 13 Blue Cross ... the largest array of individual health plan options available ... insurance on their own. The new plans were designed ... "design your own health plan" sessions, in which prospective ...
... DETROIT, April 13 Metro Parent Publishing Group ... announce the second annual "Living with Autism Workshop" on ... event is designed to educate and empower locals about ... the general public will have the unique opportunity to ...
... The American Heart Association, with support from the ... research centers to study the development and mechanisms of ... four year, the centers will be conducting studies to ... improve outcomes for heart attack and heart failure patients.The ...
... nuts, and ,Mediterranean, fare most beneficial, researchers find ... nuts and the so-called "Mediterranean" diet are heart-friendly, ... glycemic index can harm your heart, say researchers ... 2007. , The studies included 146 prospective ...
... 5,000 years ago , , MONDAY, April 13 (HealthDay News) -- ... stomach,s sake," may have been heeded more than 5,000 years ... residues found in wine jars left in the tomb of ... had been steeped in herbs including balm, coriander, mint and ...
... of antidepressants makes little difference, study finds , , MONDAY, ... that people with heart disease caused by blockage of ... finds. , That finding was to be expected, said ... in Murray, Utah, and lead author of the study, ...
Cached Medicine News:Health News:Blue Cross Launches Largest Selection of Individual Plans Available in Minnesota 2Health News:Blue Cross Launches Largest Selection of Individual Plans Available in Minnesota 3Health News:Metro Parent's Second Annual 'Living With Autism Workshop' Features Local Experts Who Are Intimately Involved in Improving the Lives of These Special Children 2Health News:Three Medical Centers Awarded Funds to Study Generation of Cardiac Muscle Cells 2Health News:Review Confirms Links Between Diet, Heart Health 2Health News:Pharoah's Wine Jar Yields Medicinal Secrets 2Health News:Pharoah's Wine Jar Yields Medicinal Secrets 3Health News:Heart Disease and Depression Up Heart Failure Risk 2
(Date:9/2/2015)... 2, 2015 CytoSorbents Corporation (NASDAQ: CTSO ... ® blood purification technology to reduce deadly uncontrolled ... CEO Dr. Phillip Chan , MD, PhD, will ... Conference (sponsored by H.C. Wainwright & Co) ... York City.  Currently, the management team ...
(Date:9/2/2015)... --  Voalte , the leader in healthcare communication technology, ... by Ascension Ventures , Cerner Capital, Inc., an ... funding closed on July 27, 2015, bringing the total ... three years. The new capital will be ... The privately held company grew revenue by 250 percent ...
(Date:9/1/2015)... BEDFORD, Mass. , Sept. 1, 2015 /PRNewswire/ ... investigating whether certain officers and directors of ConforMIS, ... of 1934.  ConforMIS is a medical technology company that ... and sell joint replacement implants that are individually sized ... View this press release on the law firm,s ...
Breaking Medicine Technology:CytoSorbents to Present at the 2015 Rodman & Renshaw Annual Global Investment Conference 2CytoSorbents to Present at the 2015 Rodman & Renshaw Annual Global Investment Conference 3CytoSorbents to Present at the 2015 Rodman & Renshaw Annual Global Investment Conference 4Voalte Raises $17 Million in Series D Financing 2Voalte Raises $17 Million in Series D Financing 3Voalte Raises $17 Million in Series D Financing 4Robbins Arroyo LLP Is Investigating the Officers and Directors of ConforMIS, Inc. (CFMS) on Behalf of Shareholders 2
Stryker Endoscopy offers a superior selection of probes and tips that interface with our suction and irrigation system....
The new PERIMOUNT Magna heart valve (bioprosthesis), with its true supra-annular design, offers optimal hemodynamics and flow characteristics for treatment of aortic heart valve disease....
... revolutionary flexibility to floor-mounted X-ray systems. ... move the C-arm around the exam ... optimal angle for cardiac and general ... cardiac flat panel detector that delivers ...
... pH.p Capsule passes through the GI tract, it ... frequencies to the SmartPill Data Receiver, a small, ... the patient (supported by either a belt or ... and pH measurement data, and elapsed and real ...
Medicine Products: