Navigation Links
3 studies confirm the value of etanercept therapy in treating juvenile idiopathic arthritis
Date:6/12/2009

Copenhagen, Denmark, Friday 12 June 2009: Three new studies have individually shown the anti-TNF (tumour necrosis factor) therapy etanercept to be effective, with a good safety profile, in children under four years of age with juvenile idiopathic arthritis (JIA), and associated with improved Health-Related Quality of Life (HRQoL) in a substantial proportion of children with JIA. The data are being presented at the Paediatric Rheumatology European Society Congress (PReS) 2009, a joint congress with the 2009 Congress of the European League Against Rheumatism (EULAR) in Copenhagen, Denmark.

The first study, conducted in Italy, showed entanercept to be effective, with a good safety profile, in children under four years of age (an as yet unlicensed patient population for the treatment). Thirty-three patients under four years of age with unresponsive JIA (24 female, 9 male) were treated with etanercept for an average of 23 months. After the first 6 months of treatment, 82% achieved the ACR Pedi 30* response and 48% achieved the ACR Pedi 70* response. There was a low rate of mild adverse events, whilst one patient temporarily suspended treatment following hospitalisation for an infection.

The second study, conducted in The Netherlands, from the Arthritis and Biological in Children (ABC) project, observed impressive improvements in the Health-Related Quality of Life (HRQoL) of 53 patients with previously refractory (unresponsive) JIA in seven Dutch centres during entanercept use of at least 27 months. These comprised both disease-specific improvements (inflamed joints, functional impairment, erythrocyte sedimentation rate (ESR), a laboratory marker of inflammation) (p<0.001) and all generic HRQoL outcomes impaired by JIA (including pain, movement and dexterity) (p<0.05).

The third study, also from The Netherlands ABC-project, showed that a substantial 57% of non-responders to etanercept at three months (12 patients from 21 non-responders of a t
'/>"/>

Contact: Rory Berrie
eularpressoffice@uk.cohnwolfe.com
44-789-439-6425
European League Against Rheumatism
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Press Releases on BPA Studies By-Pass Scientific Process
2. Studies Report More Harmful Effects From BPA
3. Studies Highlight a Revolutionary New Method of Treating Post-Operative Bruising
4. ACTEMRA(R) (tocilizumab) Studies to be Featured at the European League Against Rheumatism (EULAR) Congress
5. AstraZeneca Studies Show Relief of Nighttime Heartburn and Reduction in GERD-Related Sleep Disturbances
6. Transcept Pharmaceuticals Presents Data from Studies of Two Product Candidates at Annual Meeting of the American Psychiatric Association
7. Genomic Health to Present Multiple New Studies at the American Society of Clinical Oncology Annual Meeting
8. Studies Reveal Exposure to Pesticides During Pregnancy Increases Risk of Premature Birth, Low-Birth Weight, Neurological Problems and Diabetes
9. Rexin-G Controls Tumor Growth and Improves Survival in Chemotherapy-Resistant Sarcoma and Osteosarcoma: Phase I/II and Phase II Studies, ASCO 2009
10. 2 studies examine medical consequences of police use of force during restraint
11. Two Studies at AACE 2009 Annual Meeting Highlight Effects of Welchol(R) (colesevelam HCl) on Blood Glucose and LDL-C in Patients with Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... , ... July 02, 2015 , ... sweetFrog Enterprises, LLC. ... The opening is the first sweetFrog store located in Mississippi. The premium frozen yogurt ... in 2014. , The store, located at 104 Railroad Avenue, New Albany, MS 38652, ...
(Date:7/2/2015)... ... , ... sweetFrog Enterprises, LLC. is pleased to announce the opening of its newest location in ... State. The premium frozen yogurt chain was listed as #22 on the Inc. 500 list ... Village at Bachman Lake, is located at:, 3701 W. Northwest Highway, STE 430, Dallas, TX ...
(Date:7/2/2015)... VA (PRWEB) , ... July 02, 2015 , ... sweetFrog ... Texas. The opening is now the 19th sweetFrog store located in the Lone Star ... list of fastest growing companies in 2014. , The store, which opened July 1 ...
(Date:7/2/2015)... ... ... the recent report by JAMA Internal Medicine published on June 22, 2015, ... declared a war on obesity in the United States. , "Obesity is one of ... magnitude of this discovery. For that reason, I am declaring, along with my Health ...
(Date:7/2/2015)... VA (PRWEB) , ... July 02, 2015 , ... ... Congresswoman Donna Edwards (D-Md.) for her introduction of the Stop Overdose Stat (S.O.S.) ... introduced by Senator Jack Reed (D-R.I.), this Act seeks to decrease drug overdose ...
Breaking Medicine News(10 mins):Health News:sweetfrog Opens First Location in Mississippi 2Health News:sweetFrog Opens 18th Location in the Lone Star State 2Health News:sweetFrog Expands Texas Footprint with Location in Canton 2Health News:Samir Becic's Health Fitness Revolution Declares War Against Obesity in America 2Health News:Samir Becic's Health Fitness Revolution Declares War Against Obesity in America 3Health News:Samir Becic's Health Fitness Revolution Declares War Against Obesity in America 4Health News:AAPCC Supports the Stop Overdose Stat Act of 2015 2Health News:AAPCC Supports the Stop Overdose Stat Act of 2015 3
... with elevated CRP levels play role in metabolic syndrome, ... High levels of C-reactive protein, an inflammatory marker that ... variations in genes that control metabolism, two new studies ... of potential importance for either the treatment of cardiovascular ...
... shows nonviolent,protest by women and children, CNA claims ... With raw video from the,Labor Notes Conference ... mostly women and children, SEIU District 1199 Wisconsin ... AFL-CIO President John Sweeney,to retract his hasty statement ...
... Corporation,(NYSE: STE ) today announced the appointment of ... Robert H. Fields have joined the STERIS,Board, expanding the ... the,previous ten. Mr. Breeden will serve on the Board,s ... on the Audit and,Financial Policy Committee., "We are ...
... study from the American Cancer Society finds black and Hispanic ... smoking cessation advice and aids. The study, published in the ... finds men and those without a usual source of medical ... and receive advice to quit. , Members of several racial ...
... Denise Austin Team Up to Inspire Americans, ORRVILLE, ... Company, makers of Smucker,s(R) fruit spreads and Smucker,s(R),Natural Peanut ... You Tour,which emphasizes the importance of a balanced diet ... both areas can make a big difference,throughout each day. ...
... Two Veteran Servicemen Enjoy Extracurricular,Activities, EDISON, N.J., ... return from Iraq with debilitating injuries. But there ... from,decades-old stints in active duty., Emil Priliszh ... at,New Jersey Veterans Memorial Home in Edison, N.J., ...
Cached Medicine News:Health News:New Heart Disease Markers Discovered 2Health News:New Heart Disease Markers Discovered 3Health News:New Heart Disease Markers Discovered 4Health News:SEIU RN Dian Palmer Calls on AFL-CIO Head John Sweeney to Review Video From Dearborn Protest, Retract Statement Accepting CNA Distortions 2Health News:SEIU RN Dian Palmer Calls on AFL-CIO Head John Sweeney to Review Video From Dearborn Protest, Retract Statement Accepting CNA Distortions 3Health News:Steris Corporation Announces the Appointment of Two New Directors 2Health News:Steris Corporation Announces the Appointment of Two New Directors 3Health News:Steris Corporation Announces the Appointment of Two New Directors 4Health News:Study finds racial disparities in smoking cessation treatment 2Health News:The J.M. Smucker Company Travels the U.S. to Launch the Simple Steps To A Better You Campaign 2Health News:The J.M. Smucker Company Travels the U.S. to Launch the Simple Steps To A Better You Campaign 3Health News:The J.M. Smucker Company Travels the U.S. to Launch the Simple Steps To A Better You Campaign 4Health News:The SCOOTER Store Donates Power Chairs to Two Army Veterans With Limited Mobility 2
(Date:7/2/2015)... CHAPEL HILL, N.C. , July 2, 2015 ... their own employees to capture critical product and ... there are many benefits to employee-based studies, it ... to leverage their own internal employees to capture ... recent study by benchmarking firm, Best Practices, LLC, ...
(Date:7/2/2015)... , July 2, 2015 /PRNewswire/ - ESSA Pharma Inc. ("ESSA" ... shares have been approved for listing and trading on the ... ESSA will begin trading on NASDAQ on July 9, 2015.  ... Exchange under the symbol "EPI". As a result ... each of the Company,s outstanding special warrants issued on January ...
(Date:7/2/2015)... ResMed Inc. (NYSE: RMD ) today announced ... ended June 30, 2015 results on Thursday, July 30, 2015, ... release with ResMed,s results will be issued after 1:00 p.m. ... to discuss operating results and future outlook. The ... Pacific Time and the live webcast of the call can ...
Breaking Medicine Technology:Leveraging Employee Insights to Produce Cutting-Edge Market Research 2ESSA Pharma Inc. to Commence Trading on the NASDAQ Capital Market 2ESSA Pharma Inc. to Commence Trading on the NASDAQ Capital Market 3ESSA Pharma Inc. to Commence Trading on the NASDAQ Capital Market 4ResMed to Announce Fourth Quarter and Fiscal Year-End 2015 Results 2
... & Nephew (NYSE: SNN, LSE: SN) today announces the publication ... for total knee replacement. Published in the Journal of ... of the American Association of Hip and Knee Surgeons, this ... Smith & Nephew. To view the article, click here ...
... Jan. 11, 2012 Reportlinker.com announces that ... in its catalogue: Top ... http://www.reportlinker.com/p0572431/Top-500-Scientific-Instrument-Manufacturers--Global.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Mechanics_and_Part The Global Scientific ... Ltd. This report is an ...
Cached Medicine Technology:Patient-Matched Technology Shows Value for Patients, Surgeons and the Healthcare System 2Patient-Matched Technology Shows Value for Patients, Surgeons and the Healthcare System 3Patient-Matched Technology Shows Value for Patients, Surgeons and the Healthcare System 4Top 500 Scientific Instrument Manufacturers (Global) 2Top 500 Scientific Instrument Manufacturers (Global) 3Top 500 Scientific Instrument Manufacturers (Global) 4
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: