Navigation Links
3-D scaffold provides clean, biodegradable structure for stem cell growth
Date:2/2/2010

Medical researchers were shocked to discover that virtually all human embryonic stem cell lines being used in 2005 were contaminated. Animal byproducts used to line Petri dishes had left traces on the human cells. If those cells had been implanted in a human body they likely would have been rejected by the patient's immune system.

Even today, with new stem cell lines approved for use in medical research, there remains a risk that these cells will be contaminated in the same way. Most research labs still use animal-based "feeder layers" because it remains the cheapest and most reliable way to get stem cells to multiply.

Materials scientists at the University of Washington have now created an alternative. They built a three-dimensional scaffold out of a natural material that mimics the binding sites for stem cells, allowing the cells to reproduce on a clean, biodegradable structure. Results published in the journal Biomaterials show that human embryonic stem cells grow and multiply readily on the structure.

"The major challenge for stem cell therapy today is it's very difficult to make a lot of them with high purity," said lead author Miqin Zhang, a UW professor of materials science and engineering. "So far it seems like this material is very good for stem cell renewal."

Medical researchers hope to someday use stem cells to grow new tissues and organs. Key to the research is the fact that new cells maintain the property that holds medical promise the ability to differentiate into any of the more than 220 cell types in the adult human body.

Growing the cells in three dimensions better resembles conditions in the human body. It also allows mass production, which will be needed for any clinical applications.

"Three-dimensional scaffolds are an active area of research," said Carol Ware, a UW professor of comparative medicine and expert on stem cells. "They are not commonly used yet, but will be important to tran
'/>"/>

Contact: Hannah Hickey
hickeyh@uw.edu
206-543-2580
University of Washington
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Scaffold Could One Day Repair Damaged Hearts
2. Frost & Sullivan Lauds Pioneer Surgical Technology for Development of Tissue Scaffold E-Matrix
3. ACell and Medline Announce Exclusive Marketing and Distribution Agreement for MatriStem(TM) Proprietary Bioscaffold for Wound Care
4. Study provides hope that some transplant patients could live free of antirejection drugs
5. Study provides hope that some transplant patients could live free of anti-rejection drugs
6. USAID Provides Additional Wildfire Assistance to Greece
7. LifeMasters Provides Tips for Maintaining a Healthy Blood Cholesterol Level
8. New knock-out gene model provides molecular clues to breast cancer
9. PreMD Provides Update on 510(k) Application for PREVU(x) POC
10. SIV infection of natural hosts provides new insights into HIV disease complexity
11. Microarray provides 3 genomic guides to breast cancer treatment decisions
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
3-D scaffold provides clean, biodegradable structure for stem cell growth
(Date:8/30/2014)... Beach, Calif. (PRWEB) August 30, 2014 Insomnia ... Francis helps listeners understand how they unknowingly developed insomnia and ... have restful nights during. Tune in to the show ... The show airs live on August 30, and will ... more information on programming, go to DrCarolFrancisTalkRadio.com. , ...
(Date:8/30/2014)... 30, 2014 Hastings and Hastings, a ... located throughout Arizona is pleased to report having saved ... specific example among many cases where Hastings and Hastings ... to retain a greater portion of their settlement or ... providing a positive solution for Arizona car accident victims ...
(Date:8/30/2014)... "My niece developed a nighttime fever, and I ... fever might get worse," said an inventor from Montgomery, ... how she was doing, I developed this monitoring system." ... a child's temperature. The unit instantly alerts parents if ... medical care can be given, which is designed to ...
(Date:8/30/2014)... "I had a handicapped friend who could not walk along ... Wetumpka, Ala. "In order to help her be able to ... up with a way for her to use her crutches ... patent-pending Deezers to allow crutches to be used on uneven ... or canes at the beach. The device reduces the risk ...
(Date:8/30/2014)... WA (PRWEB) August 30, 2014 One of ... this era is the gluten-free diet. Originally meant for sufferers ... become a catchall for people who are looking to get ... However, not only is this kind of information erroneous, it ... health problems because of a drastic change in their ...
Breaking Medicine News(10 mins):Health News:Sleepless Nights, Exhausting Days, Mental Fog – Relief for Insomnia With Clinical Psychologist Dr. Carol Francis 2Health News:Hastings and Hastings Is Pleased To Report Having Saved A Client $67,100 On A Settlement Of $610,000 2Health News:“What is Gluten: Three Things You Need to Know Before Adopting a Gluten-Free Diet” Reveals What Readers Need to Know About the Benefits of a Strict Gluten Diet - Vinamy 2
... Unique off-label marketing case results in $425M ... government,s investigation,into Cephalon Inc.,s illegal marketing practices ... plea by the pharmaceutical company began,in January ... Ohio., The sales representative, Bruce Boise, ...
... Bear Bryant,Awards committee of the American Heart Association has ... has been named the,2009 winner of its, Lifetime Achievement ... Award at the Paul Bear,Bryant College Football Coaching Awards ... in Houston. The award recognizes excellence in,coaching on and ...
... pharmacy chain Walgreens has paid the United ... resolve allegations of falsely billing,the Medicaid program, ... submitted claims to Medicaid agencies in four ... both by Medicaid and by,private third-party insurance. ...
... More and more cancer patients are,looking for treatment ... of,life during difficult treatment regimens., ... at:, http://media.medialink.com/WebNR.aspx?story=35774 ) Philips Research is developing ... the effectiveness and reduce the side,effects of chemotherapy ...
... study also finds too many clinicians still using ... -- In children and teens, individual and group ... stress disorder (PTSD) and other trauma symptoms, say ... studies on the subject. , However, despite the ...
... it a “carrier of choice” for many in the medical device ... ... -- All medical devices share a critical need regardless of their ... the supply chain. For medical devices traveling to cross border ...
Cached Medicine News:Health News:Ohio Sales Rep's Information Launched Massive Government Investigation of Cephalon 2Health News:Ohio Sales Rep's Information Launched Massive Government Investigation of Cephalon 3Health News:Ohio Sales Rep's Information Launched Massive Government Investigation of Cephalon 4Health News:Barry Switzer to Receive Paul 'Bear' Bryant Lifetime Achievement Award 2Health News:Walgreens Pays U.S. $9.9 Million to Settle Medicaid Prescription Drug Allegations 2Health News:Cognitive Behavioral Therapy Best for Traumatized Youths 2Health News:Medical Device Producers Express Interest in Purolator USA's Express Service and Customer Service 2
(Date:8/29/2014)... 2014  United Therapeutics Corporation (NASDAQ: UTHR ... the District of New Jersey ... against Sandoz, Inc. regarding United Therapeutics, Remodulin ® ... that U.S. Patent No. 6,765,117 is both valid and ... its generic product until the expiration of that patent ...
(Date:8/29/2014)... -- ChemImage will present a workshop focused on hyperspectral ... Science Society,s 22 nd International Symposium on ... .  Forensic Scientists will be in attendance ... can bring to examination procedures. ... Development at ChemImage, will host a workshop during ...
(Date:8/29/2014)... MENLO PARK, Calif. , Aug. 29, 2014 ... DMPI) ("DelMar" "the Company") today announced the filing of ... recently changed its fiscal year end to June 30th ... common stock on a national securities exchange in the ... filed with the United States Securities Exchange Commission can ...
Breaking Medicine Technology:District Court Decision Received In Remodulin Patent Case 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 3DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 2DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 3DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 4DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 5
... Craftsmanship have produced the finest ... Ocutek now makes them available ... the coveted Meisterbrief certificate, which ... qualified to become Ocutek instrument ...
... of German Craftsmanship have produced ... the world. Ocutek now makes ... holders of the coveted Meisterbrief ... apprenticeship, are qualified to become ...
... Centuries of German Craftsmanship have ... in the world. Ocutek now ... Only holders of the coveted ... eight-year apprenticeship, are qualified to ...
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medicine Products: