Navigation Links
3-D map of blood vessels in cerebral cortex holds suprises
Date:6/9/2013

Blood vessels within a sensory area of the mammalian brain loop and connect in unexpected ways, a new map has revealed.

The study, published June 9 in the early online edition of Nature Neuroscience, describes vascular architecture within a well-known region of the cerebral cortex and explores what that structure means for functional imaging of the brain and the onset of a kind of dementia.

David Kleinfeld, professor of physics and neurobiology at the University of California, San Diego, and colleagues mapped blood vessels in an area of the mouse brain that receives sensory signals from the whiskers.

The organization of neural cells in this brain region is well-understood, as was a pattern of blood vessels that plunge from the surface of the brain and return from the depths, but the network in between was uncharted. Yet these tiny arterioles and venules deliver oxygen and nutrients to energy-hungry brain cells and carry away wastes.

The team traced this fine network by filling the vessels with a fluorescent gel. Then, using an automated system, developed by co-author Philbert Tsai, that removes thin layers of tissue with a laser while capturing a series of images to reconstructed the three-dimensional network of tiny vessels.

The project focused on a region of the cerebral cortex in which the nerve cells are so well known that they can be traced to individual whiskers. These neurons cluster in "barrels," one per whisker, a pattern of organization seen in other sensory areas as well.

The scientists expected each whisker barrel to match up with its own blood supply, but that was not the case. The blood vessels don't line up with the functional structure of the neurons they feed.

"This was a surprise, because the blood vessels develop in tandem with neural tissue," Kleinfeld said. Instead, microvessels beneath the surface loop and connect in patterns that don't obviously correspond to the
'/>"/>

Contact: David Kleinfeld
scinews@ucsd.edu
University of California - San Diego
Source:Eurekalert

Page: 1 2

Related medicine news :

1. US Drug Watchdog Now Urges All US Citizens with a Metal Hip Implant to get Blood Tests for Cobalt & Chromium and They Now Offer a No Cost Analysis to Check for a Failure
2. Gene-Based Blood Test Might Help Spot Colon Cancer
3. Aspirin Equals Pricier Blood Thinner for Preventing Clots: Study
4. RRVBC Summer Blood Donors to Receive Pint of Culver’s Custard
5. Enhanced white blood cells heal mice with MS-like disease
6. Researchers identify novel approach to create red blood cells, platelets in vitro
7. DrugRisks Announces Yaz Center With Latest Updates on Blood Clot Warnings and Settlements
8. Safe for stroke patients to continue blood thinners before minor surgical procedures
9. New Mayo Clinic approach could lead to blood test to diagnose Alzheimers in earliest stage
10. Alleged NuvaRing Blood-Clotting Lawsuits Update: Resource4thePeople Reports Important Hearing Scheduled for July
11. Carbondale Affordable Assisted Living Community to Host Red Cross Blood Drive
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... SPOKANE, Wash.Participants in an innovative Washington State University study ... in scenarios involving black people. But when it came ... black suspects, taking longer to pull the trigger against ... findings, published in the recent Journal of Experimental ... at explaining the disproportionate number of ethnic and racial ...
(Date:9/1/2014)... (PRWEB) September 02, 2014 UWDress.com, a ... collection of 2014 lime green bridesmaid dresses ... have been added to the company’s online category. What’s ... to 67% off. The special offer is specially launched ... of UWDress.com’s fashionable bridesmaid gowns have won great appreciation ...
(Date:9/1/2014)... Top10BestSEOHosting.com is a leading review website in ... hosting companies and announced that GreenGeeks, Arvixe and Hostgator ... , GreenGeeks ( http://www.greengeeks.com/cgi-bin/affiliates/clickthru.cgi?id=seohosts ) is one of the ... has a lot of useful products for sale. On ... low rates. , As one of the Top ...
(Date:9/1/2014)... Building on the success of the 2014 ... Breathing Academy (ASBA) has officially announced its 2015 ... The event will be taking place at the DoubleTree ... This years’ event promises to be yet another educational ... In recent years, Pro Player Health Alliance ...
(Date:9/1/2014)... and sound may be bad for your waistline. TV ... watching an excerpt from a Hollywood action film than ... been blamed for helping Americans to gain weight because ... why has been on the medium and not the ... cause people to eat more, including reading, listening to ...
Breaking Medicine News(10 mins):Health News:WSU 'deadly force' lab finds racial disparities in shootings 2Health News:WSU 'deadly force' lab finds racial disparities in shootings 3Health News:2014 Lime Green Bridesmaid Dresses Offered At UWDress.com 2Health News:The Best Reseller Hosting Suppliers in August Released by Leading Review SiteTop10BestSEOHosting.com 2Health News:Pro Player Health Alliance Confirms Big Name Speakers at 2015 American Sleep and Breathing Academy Conference 2Health News:Pro Player Health Alliance Confirms Big Name Speakers at 2015 American Sleep and Breathing Academy Conference 3Health News:Pro Player Health Alliance Confirms Big Name Speakers at 2015 American Sleep and Breathing Academy Conference 4Health News:Research letter: Viewers ate more while watching Hollywood action flick on TV 2
... rise in childhood obesity being blamed on the beverage ... substitute their sugary soft drinks// with low-calorie ... for a Healthier Generation. a joint initiative of the ... negotiated the plan with Cadbury Schweppes, Coca-Cola and PepsiCo ...
... have genetically modified mice in a study that would ... ,The research team was from the University of Texas ... results of the research were published in the journal Neuron. ... Pten in these mice.This gene has been known to be ...
... diagnostic tests for micro vascular cardiac disease on the lines ... be a good boost// to the researchers to develop novel ... afflict women much more than men. ,“Only in ... - a dysfunction of the heart’s small arteries - as ...
... food choices can play a crucial role in determining ... study // conducted by researchers at Boston University School ... The impact of this problem is more relevant in ... and healthy food is inadequate. ,‘What we ...
... competence of medical staff in the operating room, has ... and increased awareness regarding operating room safety. // Surprisingly, ... to teamwork. ,The survey, called the Safety ... questionnaire and applied to the health care environment. The ...
... sclerosis patients harbor immune cells that specifically overreact to ... mononucleosis. Although EBV has been suspected to play a ... had been largely unknown. ,Scientists think that ... with coordination and balance—is a result of the immune ...
Cached Medicine News:Health News:Nutritious Beverages to be Sold in School 2Health News:Micro vascular Disease Enabled with a Superior Test, Courtesy: Women’s Heart Progra 2Health News:Nurses Outsmart Surgeons When It Comes Safety And Team Wok 2Health News:Nurses Outsmart Surgeons When It Comes Safety And Team Wok 3Health News:EBV Might Trigger Multiple Sclerosis, Study 2Health News:EBV Might Trigger Multiple Sclerosis, Study 3Health News:EBV Might Trigger Multiple Sclerosis, Study 4
(Date:8/29/2014)... The clinical and medical insights provided by ... a product,s success or failure. Despite this, many biopharmaceutical ... – and then to coordinate activities and outreach over ... which successful KOL engagement rests. According ... inconsistencies in their KOL management systems and are working ...
(Date:8/29/2014)... DIEGO , Aug. 29, 2014   ... emerging biopharmaceutical company, announced today that Santosh Vetticaden, ... be leaving the Company, for personal reasons, in ... Chief Medical Officer of Aires Pharmaceuticals, which Mast ... former responsibilities as the Company,s interim Chief Medical ...
(Date:8/29/2014)... 29, 2014 Research and Markets ... Cancer Therapeutics Market & Pipeline Insight 2014" report ... developed to prevent and eradicate the prevalence of cancer ... are confined to low specificity, safety and large number ... for a better solution. It has been discovered that ...
Breaking Medicine Technology:Implementing a Strategic Thought Leader Management & Engagement System 2Mast Therapeutics Announces Management Change 2Mast Therapeutics Announces Management Change 3Mast Therapeutics Announces Management Change 4Global Peptide Cancer Therapeutics Market & Pipeline Insight 2014 2
... Pharmaceutical International Co., Ltd. (the "Company") (OTC Bulletin Board: ... obtained the exclusive sales rights of Thymosin Alpha 1 ... Pharmaceutical Co. I. The State Food and ... permit of Thymosin Alpha 1 Injection for Shanghai Biochemistry ...
... Health IT Services Group announced today that Acumen ... as a Complete EHR on December 30, 2010, by ... ONC-ATCB, in accordance with the applicable Eligible Provider certification ... Services. The 2011/2012 criteria support the Stage 1 meaningful ...
Cached Medicine Technology:Dongsheng Pharmaceutical International Co. Granted Exclusive Sales Rights for Thymosin Alpha 1 Injection 2Dongsheng Pharmaceutical International Co. Granted Exclusive Sales Rights for Thymosin Alpha 1 Injection 3Health IT Services Group's Acumen EHR, Version 6.0, Receives ONC-ATCB 2011/2012 Certification 2Health IT Services Group's Acumen EHR, Version 6.0, Receives ONC-ATCB 2011/2012 Certification 3
Mid-level interpretive resting ECG...
... The ECG-9010 meets IEC60601-2-51 new ... accuracy and digital filter performance. ECG ... on a Windows PC with the ... be changed for operating in other ...
The Sonic WAVE™is the first market-ready Alternative to Ultrasound...
... Critical Care Xpress is an innovative, stat ... and hematology with on-board co-oximetry and integrated ... instrument. Measured tests include pH, PCO 2 ... hematocrit and hemoglobin, sodium, potassium, chloride, ionized ...
Medicine Products: