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3-D cell culture: Making cells feel right at home
Date:3/15/2010

3-D medium produced proteins that were similar to those produced by gliobastoma tumors in mice, while cells grown in 2-D did not show this similarity.

Souza said that Nano3D Biosciences is conducting additional tests to compare how the new method stacks up against existing methods of growing 3-D cell cultures. He said he is hopeful that it will provide results that are just as good, if not better, than longstanding techniques that use 3-D scaffolds.

Raphael, a paper co-author, associate professor in bioengineering and a member of Rice's BioScience Research Collaborative, said, "The beauty of this method is that it allows natural cell-cell interactions to drive assembly of 3-D microtissue structures. The method is fairly simple and should be a good point of entry in 3-D cell culturing for any lab that's interested in drug discovery, stem cell biology, regenerative medicine or biotechnology."


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Contact: Scott Merville
smerville@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center
Source:Eurekalert

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