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25 Clinical Abstracts at National Conference Spotlight Clinical Utility of Somanetics INVOS System in Neonates
Date:5/6/2009

ings has its own drawbacks such as stunting organ development in an already fragile neonate," explains Michael Wider, PhD., co-author of two of the PAS studies and Somanetics' vice president of technology and market development. "To better confirm which patients should not be fed, investigators are studying whether cerebral/somatic oximetry values have a correlation to feeding intolerance and the eventual development of NEC."

Six PAS studies explored the technology's role in caring for neonates with patent ductus arteriosus (PDA). This is a congenital heart defect where a blood vessel called the ductus arteriosus remains open - or patent - after birth instead of closing naturally as expected. In these cases, the PDA causes abnormal blood circulation, often straining the heart and impairing blood flow throughout the body. Studies are exploring how cerebral/somatic oximetry via the INVOS System may potentially be used to help detect oxygen deficits indicative of PDAs and to help determine whether surgical or drug intervention is required.

Another study examined four drugs, commonly used in the NICU to manage a range of severe conditions, and their effect on cerebral and somatic (e.g., abdomen, kidney area, muscle) regional oxygen saturation (rSO2). The INVOS System showed that each drug produced distinct medication-specific changes to rSO2, and that this pattern was also tied to dosage.

"While drug therapy is very successful at managing numerous conditions in the NICU, clinicians may not have fully appreciated its impact on vital and non-vital organ area oxygenation because this type of data was simply not available before," adds Wider. "Arming clinicians with this previously unavailable data gives them important additional information to consider when assessing patients and care protocols."

The INVOS (In Vivo Optical Spectroscopy) Cerebral/Somatic Oximeter noninvasively monitors site-specific blood
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SOURCE Somanetics Corporation
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